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Molecular mechanism of pharmacological activation of BK channels

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (9), p.3552-3557

2012

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Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels

Nature, 2003-10, Vol.425 (6957), p.531-535

2003

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Two distinct effects of PIP2 underlie auxiliary subunit-dependent modulation of Slo1 BK channels

The Journal of general physiology, 2015-04, Vol.145 (4), p.331-343

2015

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Bilirubin oxidation end products directly alter K channels important in the regulation of vascular tone

Journal of cerebral blood flow and metabolism, 2011-01, Vol.31 (1), p.102-112

2011

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Modulation of Potassium Channel Function by Methionine Oxidation and Reduction

Proceedings of the National Academy of Sciences - PNAS, 1997-09, Vol.94 (18), p.9932-9937

1997

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Structure Elucidation and Activity of Kolossin A, the D-/L-Pentadecapeptide Product of a Giant Nonribosomal Peptide Synthetase

Angewandte Chemie International Edition, 2015-08, Vol.54 (35), p.10352-10355

2015

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Calcium channel characteristics conferred on the sodium channel by single mutations

Nature (London), 1992-04, Vol.356 (6368), p.441-443

1992

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Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3

Molecular pharmacology, 2006-07, Vol.70 (1), p.340-347

2006

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Molecular Determinants for High-Affinity Block of Human EAG Potassium Channels by Antiarrhythmic Agents

Molecular pharmacology, 2004-05, Vol.65 (5), p.1120-1129

2004

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Molecular determinants for the subtype specificity of μ-conotoxin SIIIA targeting neuronal voltage-gated sodium channels

Neuropharmacology, 2011-07, Vol.61 (1), p.105-111

2011

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A novel µ‐conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors

British journal of pharmacology, 2012-07, Vol.166 (5), p.1654-1668

2012

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Inactivation properties of voltage-gated K + channels altered by presence of β-subunit

Nature (London), 1994-05, Vol.369 (6478), p.289-294

1994

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Conformational Switch between Slow and Fast Gating Modes: Allosteric Regulation of Voltage Sensor Mobility in the EAG K + Channel

Neuron (Cambridge, Mass.), 2002-08, Vol.35 (5), p.935-949

2002

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Regulation of fast inactivation of cloned mammalian Ik(A) channels by cysteine oxidation

Nature (London), 1991-08, Vol.352 (6337), p.711-714

1991

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Isolation, molecular cloning and functional characterization of a novel β-toxin from the Venezuelan scorpion, Tityus zulianus

Toxicon (Oxford), 2004-05, Vol.43 (6), p.671-684

2004

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Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment

The Journal of physiology, 1997-08, Vol.502 (Pt 3), p.537-543

1997

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Transmembrane Channels Based on Tartaric Acid--Gramicidin A Hybrids

Science (American Association for the Advancement of Science), 1989-05, Vol.244 (4906), p.813-817

1989

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Scorpion α and α-like toxins differentially interact with sodium channels in mammalian CNS and periphery

The European journal of neuroscience, 2000-08, Vol.12 (8), p.2823-2832

2000

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Inhibition of human ether à go-go potassium channels by Ca(2+)/calmodulin

The EMBO journal, 2000-07, Vol.19 (13), p.3263-3271

2000

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Swapping of functional domains in voltage-gated K+ channels

Proceedings of the Royal Society. B, Biological sciences, 1991-08, Vol.245 (1313), p.101-107

1991

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A Single Negative Charge within the Pore Region of a cGMP-Gated Channel Controls Rectification, Ca2+Blockage, and Ionic Selectivity

Proceedings of the National Academy of Sciences - PNAS, 1994-02, Vol.91 (3), p.1109-1113

1994

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TRPgamma channels are inhibited by cAMP and contribute to pacemaking in neurosecretory insect neurons

The Journal of biological chemistry, 2006-02, Vol.281 (6), p.3227-3236

2006

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Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2

The EMBO journal, 2008-12, Vol.27 (23), p.3164

2008

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Prevention of acute allograft rejection by antibody targeting of TIRC7, a novel T cell membrane protein

Immunity (Cambridge, Mass.), 1998-10, Vol.9 (4), p.509-518

1998

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Endogenous superantigen expression controlled by a novel promoter in the MMTV long terminal repeat

Nature (London), 1993-07, Vol.364 (6433), p.154-158

1993

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Molecular mechanism of pharmacological activation of BK channels

Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels

Two distinct effects of PIP2 underlie auxiliary subunit-dependent modulation of Slo1 BK channels

Bilirubin oxidation end products directly alter K channels important in the regulation of vascular tone

Modulation of Potassium Channel Function by Methionine Oxidation and Reduction

Structure Elucidation and Activity of Kolossin A, the D-/L-Pentadecapeptide Product of a Giant Nonribosomal Peptide Synthetase

Calcium channel characteristics conferred on the sodium channel by single mutations

Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3

Molecular Determinants for High-Affinity Block of Human EAG Potassium Channels by Antiarrhythmic Agents

Molecular determinants for the subtype specificity of μ-conotoxin SIIIA targeting neuronal voltage-gated sodium channels

A novel µ‐conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors

Inactivation properties of voltage-gated K + channels altered by presence of β-subunit

Conformational Switch between Slow and Fast Gating Modes: Allosteric Regulation of Voltage Sensor Mobility in the EAG K + Channel

Regulation of fast inactivation of cloned mammalian Ik(A) channels by cysteine oxidation

Isolation, molecular cloning and functional characterization of a novel β-toxin from the Venezuelan scorpion, Tityus zulianus

Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment

Transmembrane Channels Based on Tartaric Acid--Gramicidin A Hybrids

Scorpion α and α-like toxins differentially interact with sodium channels in mammalian CNS and periphery

Inhibition of human ether à go-go potassium channels by Ca(2+)/calmodulin

Swapping of functional domains in voltage-gated K+ channels

A Single Negative Charge within the Pore Region of a cGMP-Gated Channel Controls Rectification, Ca2+Blockage, and Ionic Selectivity

TRPgamma channels are inhibited by cAMP and contribute to pacemaking in neurosecretory insect neurons

Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2

Prevention of acute allograft rejection by antibody targeting of TIRC7, a novel T cell membrane protein

Endogenous superantigen expression controlled by a novel promoter in the MMTV long terminal repeat

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