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Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks

The Journal of biological chemistry, 2019-11, Vol.294 (44), p.16198-16213

2019

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Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer

The Journal of biological chemistry, 2020-01, Vol.295 (4), p.1105-1119

2020

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IQGAP1 Protein Regulates Nuclear Localization of β-Catenin via Importin-β5 Protein in Wnt Signaling

The Journal of biological chemistry, 2013-12, Vol.288 (51), p.36351-36360

2013

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A Mouse Homologue of the Drosophila Tumor Suppressor l(2)tid Gene Defines a Novel Ras GTPase-activating Protein (RasGAP)-binding Protein

The Journal of biological chemistry, 2001-04, Vol.276 (16), p.13087-13095

2001

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Phospholipase D-mediated Activation of IQGAP1 through Rac1 Regulates Hyperoxia-induced p47phox Translocation and Reactive Oxygen Species Generation in Lung Endothelial Cells

The Journal of biological chemistry, 2009-05, Vol.284 (22), p.15339-15352

2009

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The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1

The Journal of biological chemistry, 2006-02, Vol.281 (8), p.4903-4910

2006

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The RasGAP N-terminal fragment generated by caspase cleavage protects cells in a Ras/PI3K/Akt-dependent manner that does not rely on NFkappa B activation

The Journal of biological chemistry, 2002-04, Vol.277 (17), p.14641-14646

2002

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Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras

The Journal of biological chemistry, 2002-11, Vol.277 (45), p.43024-43032

2002

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Evidence that Llck-mediated phosphorylation of p56dok and p62dok may play a role in CD2 signaling

The Journal of biological chemistry, 2000-05, Vol.275 (19), p.14590

2000

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Mechanism of GTPase activation of a prokaryotic small Ras-like GTPase MglA by an asymmetrically interacting MglB dimer

The Journal of biological chemistry, 2024-04, Vol.300 (4), p.107197-107197, Article 107197

2024

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Lipid Products of Phosphoinositide 3-Kinase Interact with Rac1 GTPase and Stimulate GDP Dissociation

The Journal of biological chemistry, 1998-11, Vol.273 (46), p.30279-30286

1998

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SH3 Domain-dependent Association of Huntingtin with Epidermal Growth Factor Receptor Signaling Complexes

The Journal of biological chemistry, 1997-03, Vol.272 (13), p.8121-8124

1997

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Calmodulin Activates Phosphatidylinositol 3-Kinase

The Journal of biological chemistry, 1997-11, Vol.272 (45), p.28183-28186

1997

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Calmodulin modulates the interaction between IQGAP1 and Cdc42. Identification of IQGAP1 by nanoelectrospray tandem mass spectrometry

The Journal of biological chemistry, 1997-06, Vol.272 (24), p.15419-15425

1997

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RNA1 Encodes a GTPase-activating Protein Specific for Gsp1p, the Ran/TC4 Homologue of Saccharomyces cerevisiae

The Journal of biological chemistry, 1995-05, Vol.270 (20), p.11860-11865

1995

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The Activation of Rac1 by M3 Muscarinic Acetylcholine Receptors Involves the Translocation of Rac1 and IQGAP1 to Cell Junctions and Changes in the Composition of Protein Complexes Containing Rac1, IQGAP1, and Actin

The Journal of biological chemistry, 2002-09, Vol.277 (36), p.33081-33091

2002

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Two SH2 Domains of p120 Ras GTPase-activating Protein Bind Synergistically to Tyrosine Phosphorylated p190 Rho GTPase-activating Protein

The Journal of biological chemistry, 1995-07, Vol.270 (30), p.17947-17952

1995

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Analyzing the Role of the Putative Inositol 1,3,4,5-Tetrakisphosphate Receptor GAP1IP4BP in Intracellular Ca2+ Homeostasis

The Journal of biological chemistry, 2002-12, Vol.277 (50), p.48779-48785

2002

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Activated Src tyrosine kinase phosphorylates Tyr-457 of bovine GTPase-activating protein (GAP) in vitro and the corresponding residue of rat GAP in vivo

The Journal of biological chemistry, 1992-08, Vol.267 (24), p.17194-17200

1992

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RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha

The Journal of biological chemistry, 1998-10, Vol.273 (40), p.26008-26013

1998

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The Ca2+-dependent lipid binding domain of P120GAP mediates protein-protein interactions with Ca2+-dependent membrane-binding proteins. Evidence for a direct interaction between annexin VI and P120GAP

The Journal of biological chemistry, 1996-10, Vol.271 (40), p.24333-24336

1996

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Evidence that Ha-Ras mediates two distinguishable intracellular signals activated by v-Src

The Journal of biological chemistry, 1992-09, Vol.267 (25), p.17635-17639

1992

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p130Cas Regulates the Activity of AND-34, a Novel Ral, Rap1, and R-Ras Guanine Nucleotide Exchange Factor

The Journal of biological chemistry, 2000-09, Vol.275 (39), p.30118-30123

2000

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Angiotensin II controls p21ras activity via pp60c-src

The Journal of biological chemistry, 1996-04, Vol.271 (17), p.10329-10333

1996

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Structural Differences in the Minimal Catalytic Domains of the GTPase-activating Proteins p120GAP and Neurofibromin

The Journal of biological chemistry, 1996-07, Vol.271 (27), p.16409-16415

1996

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Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks

Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer

IQGAP1 Protein Regulates Nuclear Localization of β-Catenin via Importin-β5 Protein in Wnt Signaling

A Mouse Homologue of the Drosophila Tumor Suppressor l(2)tid Gene Defines a Novel Ras GTPase-activating Protein (RasGAP)-binding Protein

Phospholipase D-mediated Activation of IQGAP1 through Rac1 Regulates Hyperoxia-induced p47phox Translocation and Reactive Oxygen Species Generation in Lung Endothelial Cells

The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1

The RasGAP N-terminal fragment generated by caspase cleavage protects cells in a Ras/PI3K/Akt-dependent manner that does not rely on NFkappa B activation

Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras

Evidence that Llck-mediated phosphorylation of p56dok and p62dok may play a role in CD2 signaling

Mechanism of GTPase activation of a prokaryotic small Ras-like GTPase MglA by an asymmetrically interacting MglB dimer

Lipid Products of Phosphoinositide 3-Kinase Interact with Rac1 GTPase and Stimulate GDP Dissociation

SH3 Domain-dependent Association of Huntingtin with Epidermal Growth Factor Receptor Signaling Complexes

Calmodulin Activates Phosphatidylinositol 3-Kinase

Calmodulin modulates the interaction between IQGAP1 and Cdc42. Identification of IQGAP1 by nanoelectrospray tandem mass spectrometry

RNA1 Encodes a GTPase-activating Protein Specific for Gsp1p, the Ran/TC4 Homologue of Saccharomyces cerevisiae

The Activation of Rac1 by M3 Muscarinic Acetylcholine Receptors Involves the Translocation of Rac1 and IQGAP1 to Cell Junctions and Changes in the Composition of Protein Complexes Containing Rac1, IQGAP1, and Actin

Two SH2 Domains of p120 Ras GTPase-activating Protein Bind Synergistically to Tyrosine Phosphorylated p190 Rho GTPase-activating Protein

Analyzing the Role of the Putative Inositol 1,3,4,5-Tetrakisphosphate Receptor GAP1IP4BP in Intracellular Ca2+ Homeostasis

Activated Src tyrosine kinase phosphorylates Tyr-457 of bovine GTPase-activating protein (GAP) in vitro and the corresponding residue of rat GAP in vivo

RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha

The Ca2+-dependent lipid binding domain of P120GAP mediates protein-protein interactions with Ca2+-dependent membrane-binding proteins. Evidence for a direct interaction between annexin VI and P120GAP

Evidence that Ha-Ras mediates two distinguishable intracellular signals activated by v-Src

p130Cas Regulates the Activity of AND-34, a Novel Ral, Rap1, and R-Ras Guanine Nucleotide Exchange Factor

Angiotensin II controls p21ras activity via pp60c-src

Structural Differences in the Minimal Catalytic Domains of the GTPase-activating Proteins p120GAP and Neurofibromin

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