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Stearoly-CoA desaturase 1 differentiates early and advanced dengue virus infections and determines virus particle infectivity

PLoS pathogens, 2018-08, Vol.14 (8), p.e1007261-e1007261

2018

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Antiinfectives targeting enzymes and the proton motive force

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (51), p.E7073-E7082

2015

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Inhibition of the First Step in Synthesis of the Mycobacterial Cell Wall Core, Catalyzed by the GlcNAc-1-phosphate Transferase WecA, by the Novel Caprazamycin Derivative CPZEN-45

The Journal of biological chemistry, 2013-10, Vol.288 (42), p.30309-30319

2013

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Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases

Journal of medicinal chemistry, 2014-04, Vol.57 (7), p.3126-3139

2014

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Characterization of MenA (isoprenyl diphosphate:1,4-dihydroxy-2-naphthoate isoprenyltransferase) from Mycobacterium tuberculosis

PloS one, 2019-04, Vol.14 (4), p.e0214958

2019

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Discovery of Selective Menaquinone Biosynthesis Inhibitors against Mycobacterium tuberculosis

Journal of medicinal chemistry, 2012-04, Vol.55 (8), p.3739-3755

2012

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Decavanadate Inhibits Mycobacterial Growth More Potently Than Other Oxovanadates

Frontiers in chemistry, 2018-11, Vol.6, p.519-519

2018

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Lipidomic analyses of Mycobacterium tuberculosis based on accurate mass measurements and the novel “Mtb LipidDB”[S]

Journal of lipid research, 2011-05, Vol.52 (5), p.861-872

2011

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A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria

Science signaling, 2012-01, Vol.5 (208), p.ra7

2012

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Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis

Nature communications, 2017-03, Vol.8 (1), p.14414-14414, Article 14414

2017

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TetR-like regulator BP1026B_II1561 controls aromatic amino acid biosynthesis and intracellular pathogenesis in Burkholderia pseudomallei

Frontiers in microbiology, 2024-08, Vol.15, p.1441330

2024

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Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non-replicating persistence

Molecular microbiology, 2009-04, Vol.72 (1), p.85-97

2009

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Interactions of Truncated Menaquinones in Lipid Monolayers and Bilayers

International journal of molecular sciences, 2021-09, Vol.22 (18), p.9755

2021

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Inhibition of 1-Deoxy-d-Xylulose-5-Phosphate Reductoisomerase by Lipophilic Phosphonates: SAR, QSAR, and Crystallographic Studies

Journal of medicinal chemistry, 2011-07, Vol.54 (13), p.4721-4734

2011

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Identification of the namH Gene, Encoding the Hydroxylase Responsible for the N-Glycolylation of the Mycobacterial Peptidoglycan

The Journal of biological chemistry, 2005-01, Vol.280 (1), p.326-333

2005

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Decaprenylphosphoryl Arabinofuranose, the Donor of the d-Arabinofuranosyl Residues of Mycobacterial Arabinan, Is Formed via a Two-Step Epimerization of Decaprenylphosphoryl Ribose

Journal of Bacteriology, 2005-12, Vol.187 (23), p.8020-8025

2005

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Discovery of 1,4-Didydroxy-2-naphthoate Prenyltransferase Inhibitors: New Drug Leads for Multidrug-Resistant Gram-Positive Pathogens

Journal of medicinal chemistry, 2007-08, Vol.50 (17), p.3973-3975

2007

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Pyrazinoic acid, the active form of the anti-tuberculosis drug pyrazinamide, and aromatic carboxylic acid analogs are protonophores

Frontiers in molecular biosciences, 2024-02, Vol.11, p.1350699-1350699

2024

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Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis

Journal of the American Chemical Society, 2014-02, Vol.136 (7), p.2892-2896

2014

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Targeting the formation of the cell wall core of M. tuberculosis

Infectious disorders drug targets, 2007-06, Vol.7 (2), p.182-202

2007

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Electron Transport Lipids Fold Within Membrane-Like Interfaces

Frontiers in chemistry, 2022-03, Vol.10, p.827530

2022

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Export-Mediated Assembly of Mycobacterial Glycoproteins Parallels Eukaryotic Pathways

Science (American Association for the Advancement of Science), 2005-08, Vol.309 (5736), p.941-943

2005

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Synthesis and Characterization of Partially and Fully Saturated Menaquinone Derivatives

ACS omega, 2018-11, Vol.3 (11), p.14889-14901

2018

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Partial Saturation of Menaquinone in Mycobacterium tuberculosis: Function and Essentiality of a Novel Reductase, MenJ

ACS central science, 2015-09, Vol.1 (6), p.292-302

2015

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The Mycobacterium tuberculosis MEP (2 C -methyl- d -erythritol 4-phosphate) pathway as a new drug target

Tuberculosis (Edinburgh, Scotland), 2009-01, Vol.89 (1), p.1-11

2009

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Stearoly-CoA desaturase 1 differentiates early and advanced dengue virus infections and determines virus particle infectivity

Antiinfectives targeting enzymes and the proton motive force

Inhibition of the First Step in Synthesis of the Mycobacterial Cell Wall Core, Catalyzed by the GlcNAc-1-phosphate Transferase WecA, by the Novel Caprazamycin Derivative CPZEN-45

Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases

Characterization of MenA (isoprenyl diphosphate:1,4-dihydroxy-2-naphthoate isoprenyltransferase) from Mycobacterium tuberculosis

Discovery of Selective Menaquinone Biosynthesis Inhibitors against Mycobacterium tuberculosis

Decavanadate Inhibits Mycobacterial Growth More Potently Than Other Oxovanadates

Lipidomic analyses of Mycobacterium tuberculosis based on accurate mass measurements and the novel “Mtb LipidDB”[S]

A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria

Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis

TetR-like regulator BP1026B_II1561 controls aromatic amino acid biosynthesis and intracellular pathogenesis in Burkholderia pseudomallei

Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non-replicating persistence

Interactions of Truncated Menaquinones in Lipid Monolayers and Bilayers

Inhibition of 1-Deoxy-d-Xylulose-5-Phosphate Reductoisomerase by Lipophilic Phosphonates: SAR, QSAR, and Crystallographic Studies

Identification of the namH Gene, Encoding the Hydroxylase Responsible for the N-Glycolylation of the Mycobacterial Peptidoglycan

Decaprenylphosphoryl Arabinofuranose, the Donor of the d-Arabinofuranosyl Residues of Mycobacterial Arabinan, Is Formed via a Two-Step Epimerization of Decaprenylphosphoryl Ribose

Discovery of 1,4-Didydroxy-2-naphthoate Prenyltransferase Inhibitors: New Drug Leads for Multidrug-Resistant Gram-Positive Pathogens

Pyrazinoic acid, the active form of the anti-tuberculosis drug pyrazinamide, and aromatic carboxylic acid analogs are protonophores

Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis

Targeting the formation of the cell wall core of M. tuberculosis

Electron Transport Lipids Fold Within Membrane-Like Interfaces

Export-Mediated Assembly of Mycobacterial Glycoproteins Parallels Eukaryotic Pathways

Synthesis and Characterization of Partially and Fully Saturated Menaquinone Derivatives

Partial Saturation of Menaquinone in Mycobacterium tuberculosis: Function and Essentiality of a Novel Reductase, MenJ

The Mycobacterium tuberculosis MEP (2 C -methyl- d -erythritol 4-phosphate) pathway as a new drug target

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