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Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance

PloS one, 2015-05, Vol.10 (5), p.e0126350

2015

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Efflux-Mediated Antifungal Drug Resistance

Clinical Microbiology Reviews, 2009-04, Vol.22 (2), p.291-321

2009

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Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (10), p.3865-3870

2014

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Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals

PloS one, 2016-12, Vol.11 (12), p.e0167485-e0167485

2016

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Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases

Journal of fungi (Basel), 2021-01, Vol.7 (2), p.67

2021

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The Monoamine Oxidase A Inhibitor Clorgyline Is a Broad-Spectrum Inhibitor of Fungal ABC and MFS Transporter Efflux Pump Activities Which Reverses the Azole Resistance of Candida albicans and Candida glabrata Clinical Isolates

Antimicrobial Agents and Chemotherapy, 2012-03, Vol.56 (3), p.1508-1515

2012

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Correction: Monk, B.C.; Keniya, M.V. Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases. J. Fungi 2021, 7 , 67

Journal of fungi (Basel), 2021-11, Vol.7 (12), p.1011

2021

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Crystal Structures of Full-Length Lanosterol 14α-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provide Tools for Antifungal Discovery

Antimicrobial agents and chemotherapy, 2018-11, Vol.62 (11)

2018

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Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design

Biochimica et biophysica acta. Proteins and proteomics, 2020-03, Vol.1868 (3), p.140206, Article 140206

2020

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Drug Resistance Is Conferred on the Model Yeast Saccharomyces cerevisiae by Expression of Full-Length Melanoma-Associated Human ATP-Binding Cassette Transporter ABCB5

Molecular pharmaceutics, 2014-10, Vol.11 (10), p.3452-3462

2014

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Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14α-Demethylase

Antimicrobial agents and chemotherapy, 2015-08, Vol.59 (8), p.4982-4989

2015

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Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase

Scientific reports, 2016-05, Vol.6 (1), p.26213-26213, Article 26213

2016

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Heterologous Expression of Full-Length Lanosterol 14α-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provides Tools for Antifungal Discovery

Antimicrobial agents and chemotherapy, 2018-11, Vol.62 (11)

2018

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Azole Resistance Reduces Susceptibility to the Tetrazole Antifungal VT-1161

Antimicrobial agents and chemotherapy, 2019-01, Vol.63 (1)

2019

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Attenuated apoptotic BAX expression as a xenobiotic reporter in Saccharomyces cerevisiae

FEMS yeast research, 2019-08, Vol.19 (5), p.1

2019

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Targeting efflux pumps to overcome antifungal drug resistance

Future medicinal chemistry, 2016-08, Vol.8 (12), p.1485-1501

2016

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Functional Expression of Recombinant ICandida auris/I Proteins in ISaccharomyces cerevisiae/I Enables Azole Susceptibility Evaluation and Drug Discovery

Journal of fungi (Basel), 2023-01, Vol.9 (2)

2023

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Exploring ICryptococcus neoformans/I CYP51 and Its Cognate Reductase as a Drug Target

Journal of fungi (Basel), 2022-11, Vol.8 (12)

2022

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Clorgyline Analogs Synergize with Azoles against Drug Efflux in ICandida auris/I

Journal of fungi (Basel), 2023-06, Vol.9 (6)

2023

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Structural and Functional Elucidation of Yeast Lanosterol 14[alpha]-Demethylase in Complex with Agrochemical Antifungals.(Research Article)

PloS one, 2016-12, Vol.11 (12), p.e0167485

2016

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Heterologous expression of C andida albicans Pma1p in S accharomyces cerevisiae

FEMS yeast research, 2013-05, Vol.13 (3), p.302-311

2013

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Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance: e0126350

PloS one, 2015-05, Vol.10 (5)

2015

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Crystallization of Erg11p – the cytochrome P450 target of triazole antifungals

Acta crystallographica. Section A, Foundations of crystallography, 2013-08, Vol.69 (a1), p.s62-s62

2013

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Using Yeast to Discover Inhibitors of Multidrug Efflux in Candida albicans

Candida Albicans: Cellular and Molecular Biology, 2017, p.491-543

2017

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Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance

Efflux-Mediated Antifungal Drug Resistance

Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer

Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals

Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases

The Monoamine Oxidase A Inhibitor Clorgyline Is a Broad-Spectrum Inhibitor of Fungal ABC and MFS Transporter Efflux Pump Activities Which Reverses the Azole Resistance of Candida albicans and Candida glabrata Clinical Isolates

Correction: Monk, B.C.; Keniya, M.V. Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases. J. Fungi 2021, 7 , 67

Crystal Structures of Full-Length Lanosterol 14α-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provide Tools for Antifungal Discovery

Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design

Drug Resistance Is Conferred on the Model Yeast Saccharomyces cerevisiae by Expression of Full-Length Melanoma-Associated Human ATP-Binding Cassette Transporter ABCB5

Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14α-Demethylase

Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase

Heterologous Expression of Full-Length Lanosterol 14α-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provides Tools for Antifungal Discovery

Azole Resistance Reduces Susceptibility to the Tetrazole Antifungal VT-1161

Attenuated apoptotic BAX expression as a xenobiotic reporter in Saccharomyces cerevisiae

Targeting efflux pumps to overcome antifungal drug resistance

Functional Expression of Recombinant ICandida auris/I Proteins in ISaccharomyces cerevisiae/I Enables Azole Susceptibility Evaluation and Drug Discovery

Exploring ICryptococcus neoformans/I CYP51 and Its Cognate Reductase as a Drug Target

Clorgyline Analogs Synergize with Azoles against Drug Efflux in ICandida auris/I

Structural and Functional Elucidation of Yeast Lanosterol 14[alpha]-Demethylase in Complex with Agrochemical Antifungals.(Research Article)

Heterologous expression of C andida albicans Pma1p in S accharomyces cerevisiae

Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance: e0126350

Crystallization of Erg11p – the cytochrome P450 target of triazole antifungals

Using Yeast to Discover Inhibitors of Multidrug Efflux in Candida albicans

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