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Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation

Nature structural & molecular biology, 2020-04, Vol.27 (4), p.363

2020

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DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer

Molecular therapy, 2023-02, Vol.31 (2), p.471-486

2023

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Local unfolding of the HSP27 monomer regulates chaperone activity

Nature communications, 2019-03, Vol.10 (1), p.1068-1068, Article 1068

2019

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Characterization of heat shock protein 27 in extracellular vesicles: a potential anti‐inflammatory therapy

The FASEB journal, 2019-02, Vol.33 (2), p.1617-1630

2019

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HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation

The Journal of biological chemistry, 2018-02, Vol.293 (8), p.2687-2700

2018

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Mammalian HspB1 (Hsp27) is a molecular sensor linked to the physiology and environment of the cell

Cell stress & chaperones, 2017-07, Vol.22 (4), p.517-529

Arrigo, André-Patrick

2017

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The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

The Journal of biological chemistry, 2017-01, Vol.292 (2), p.672-684

2017

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Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood–brain barrier disruption after ischemic brain injury

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (7), p.E1243-E1252

2017

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microRNA‐577 suppresses tumor growth and enhances chemosensitivity in colorectal cancer

Journal of biochemical and molecular toxicology, 2017-06, Vol.31 (6), p.n/a

2017

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Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

Nature communications, 2018-11, Vol.9 (1), p.4563-11, Article 4563

2018

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Hsp27 as a therapeutic target in cancers

Current drug targets, 2014-04, Vol.15 (4), p.423

2014

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Phosphorylated Heat Shock Protein 27 Inhibits Lipopolysaccharide-Induced Inflammation in Thp1 Cells by Promoting TLR4 Endocytosis, Ubiquitination, and Degradation

Inflammation, 2019-10, Vol.42 (5), p.1788-1799

2019

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Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP

Cell stress & chaperones, 2022-03, Vol.27 (2), p.177-188

2022

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The miR-15b-Smurf2-HSP27 axis promotes pulmonary fibrosis

Journal of biomedical science, 2023-01, Vol.30 (1), p.2-2, Article 2

2023

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Schisandrin B ameliorates high-glucose-induced vascular endothelial cells injury by regulating the Noxa/Hsp27/NF-κB signaling pathway

Biochemistry and cell biology, 2019-12, Vol.97 (6), p.681

2019

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MS4A3-HSP27 target pathway reveals potential for haematopoietic disorder treatment in alimentary toxic aleukia

Cell biology and toxicology, 2023-02, Vol.39 (1), p.201-216

2023

Volltextzugriff (PDF)

Effect of Heat Shock Preconditioning on Pressure Injury Prevention via Hsp27 Upregulation in Rat Models

International journal of molecular sciences, 2022-08, Vol.23 (16), p.8955

2022

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Exosomal Hsp27 protein are associated with heart failure in STZ-induced type 1 diabetic rats

International journal of biological macromolecules, 2024-07, p.133772, Article 133772

2024

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Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in adult rats

Brain pathology (Zurich, Switzerland), 2017-11, Vol.27 (6), p.822-838

2017

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Biophysical analyses and functional implications of the interaction between Heat Shock Protein 27 and antibodies to HSP27

Biochimica et biophysica acta. General subjects, 2019-10, Vol.1863 (10), p.1536-1546

2019

Volltextzugriff (PDF)

Characterization of human small heat shock protein HSPB1 α-crystallin domain localized mutants associated with hereditary motor neuron diseases

Scientific reports, 2018-01, Vol.8 (1), p.688-15, Article 688

2018

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A Dual Targeting Dendrimer-Mediated siRNA Delivery System for Effective Gene Silencing in Cancer Therapy

Journal of the American Chemical Society, 2018-11, Vol.140 (47), p.16264-16274

2018

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Promoting siRNA delivery via enhanced cellular uptake using an arginine-decorated amphiphilic dendrimer

Nanoscale, 2015-03, Vol.7 (9), p.3867-3875

2015

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Heat Shock Proteins Promote Cancer: It's a Protection Racket

Trends in biochemical sciences (Amsterdam. Regular ed.), 2016-04, Vol.41 (4), p.311-323

2016

Volltextzugriff (PDF)

Quantitative proteomic analysis reveals potential diagnostic markers and pathways involved in pathogenesis of renal cell carcinoma

Oncotarget, 2014-01, Vol.5 (2), p.506-518

2014

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1 – 25 von 2.688

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Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation

DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer

Local unfolding of the HSP27 monomer regulates chaperone activity

Characterization of heat shock protein 27 in extracellular vesicles: a potential anti‐inflammatory therapy

HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation

Mammalian HspB1 (Hsp27) is a molecular sensor linked to the physiology and environment of the cell

The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood–brain barrier disruption after ischemic brain injury

microRNA‐577 suppresses tumor growth and enhances chemosensitivity in colorectal cancer

Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

Hsp27 as a therapeutic target in cancers

Phosphorylated Heat Shock Protein 27 Inhibits Lipopolysaccharide-Induced Inflammation in Thp1 Cells by Promoting TLR4 Endocytosis, Ubiquitination, and Degradation

Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP

The miR-15b-Smurf2-HSP27 axis promotes pulmonary fibrosis

Schisandrin B ameliorates high-glucose-induced vascular endothelial cells injury by regulating the Noxa/Hsp27/NF-κB signaling pathway

MS4A3-HSP27 target pathway reveals potential for haematopoietic disorder treatment in alimentary toxic aleukia

Effect of Heat Shock Preconditioning on Pressure Injury Prevention via Hsp27 Upregulation in Rat Models

Exosomal Hsp27 protein are associated with heart failure in STZ-induced type 1 diabetic rats

Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in adult rats

Biophysical analyses and functional implications of the interaction between Heat Shock Protein 27 and antibodies to HSP27

Characterization of human small heat shock protein HSPB1 α-crystallin domain localized mutants associated with hereditary motor neuron diseases

A Dual Targeting Dendrimer-Mediated siRNA Delivery System for Effective Gene Silencing in Cancer Therapy

Promoting siRNA delivery via enhanced cellular uptake using an arginine-decorated amphiphilic dendrimer

Heat Shock Proteins Promote Cancer: It's a Protection Racket

Quantitative proteomic analysis reveals potential diagnostic markers and pathways involved in pathogenesis of renal cell carcinoma

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