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Association of Integrase, Matrix, and Reverse Transcriptase Antigens of Human Immunodeficiency Virus Type 1 with Viral Nucleic Acids Following Acute Infection

Proceedings of the National Academy of Sciences - PNAS, 1993-07, Vol.90 (13), p.6125-6129

1993

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Structure-Based Design of HIV Protease Inhibitors: Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors

Journal of medicinal chemistry, 1996-10, Vol.39 (22), p.4349-4353

1996

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Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant: Lead Identification and SAR of 3- and 4-Substituted Derivatives

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.1034-1040

2000

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A Drug Resistance Mutation in the Inhibitor Binding Pocket of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Impairs DNA Synthesis and RNA Degradation

Biochemistry (Easton), 1996-07, Vol.35 (30), p.9737-9745

1996

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A recombinant ribonuclease H domain of HIV-1 reverse transcriptase that is enzymatically active

The Journal of biological chemistry, 1991-11, Vol.266 (31), p.20583-20585

1991

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Functional characterization of RNA-dependent DNA polymerase and RNase H activities of a recombinant HIV reverse transcriptase

Biochemistry (Easton), 1991-03, Vol.30 (10), p.2651-2655

1991

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Oxazolidinones: a new class of antibacterials

Current Opinion in Pharmacology, 2001-10, Vol.1 (5), p.470-476

2001

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Steady-state kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-87201E

The Journal of biological chemistry, 1993-03, Vol.268 (9), p.6119-6124

1993

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Pyrimidine Thioethers: A Novel Class of HIV-1 Reverse Transcriptase Inhibitors with Activity Against BHAP-Resistant HIV

Journal of medicinal chemistry, 1998-09, Vol.41 (20), p.3793-3803

1998

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Treatment of human immunodeficiency virus type 1 (HIV-1)-infected cells with combinations of HIV-1-specific inhibitors results in a different resistance pattern than does treatment with single-drug therapy

Journal of Virology, 1993-09, Vol.67 (9), p.5353-5359

1993

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Kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-88204E

Biochemistry (Easton), 1993-07, Vol.32 (26), p.6548-6554

1993

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Targeting Delavirdine/Atevirdine Resistant HIV-1: Identification of (Alkylamino)piperidine-Containing Bis(heteroaryl)piperazines as Broad Spectrum HIV-1 Reverse Transcriptase Inhibitors

Journal of medicinal chemistry, 1996-09, Vol.39 (19), p.3769-3789

1996

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The binding of a novel bisheteroarylpiperazine mediates inhibition of human immunodeficiency virus type 1 reverse transcriptase

The Journal of biological chemistry, 1992-01, Vol.267 (1), p.27-30

1992

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Loss of Platelet-Derived Growth Factor-Stimulated Phospholipase Activity in NIH-3T3 Cells Expressing the EJ-ras Oncogene

Proceedings of the National Academy of Sciences - PNAS, 1987-01, Vol.84 (2), p.546-550

1987

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Characterization of the p68/p58 Heterodimer of Human Immunodeficiency Virus Type 2 Reverse Transcriptase

Biochemistry (Easton), 1996-02, Vol.35 (6), p.1911-1917

1996

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The Differential Processing of Homodimers of Reverse Transcriptases from Human Immunodeficiency Viruses Type 1 and 2 Is a Consequence of the Distinct Specificities of the Viral Proteases

The Journal of biological chemistry, 1995-06, Vol.270 (22), p.13573-13579

1995

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Inhibition of Human Immunodeficiency Virus Type 1 Replication In Vitro by the Bisheteroarylpiperzine Atevirdine (U-87201E) in Combination with Zidovudine or Didanosine

The Journal of infectious diseases, 1993-08, Vol.168 (2), p.318-326

1993

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An active recombinant p15 RNase H domain is functionally distinct from the RNase H domain associated with human immunodeficiency virus type 1 reverse transcriptase

The Journal of biological chemistry, 1994-08, Vol.269 (34), p.21741-21747

1994

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Escherichia coli expression, purification, and biological activity of a truncated soluble CD4

AIDS research and human retroviruses, 1990-04, Vol.6 (4), p.465-479

1990

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Reduced Hormone-Stimulated Adenylate Cyclase Activity in NIH-3T3 Cells Expressing the EJ Human Bladder ras Oncogene

Proceedings of the National Academy of Sciences - PNAS, 1986-06, Vol.83 (11), p.3703-3707

1986

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Denaturation/refolding of purified recombinant HIV reverse transcriptase yields monomeric enzyme with high enzymatic activity

AIDS research and human retroviruses, 1990-03, Vol.6 (3), p.329-340

1990

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Effects of a soluble CD4 and CD4-Pseudomonas exotoxn A chimeric protein on human peripheral blood lymphocytes : lymphocyte activation and anti-HIV activity in vitro

Antiviral research, 1991, Vol.16 (3), p.267-279

1991

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Expression and characterization of chimeric rDNA proteins engineered for purification and enzymatic cleavage

Protein expression and purification, 1991-04, Vol.2 (2), p.205-213

1991

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Effects of a soluble CD4 and CD4- Pseudomonas exotoxin A chimeric protein on human peripheral blood lymphocytes: Lymphocyte activation and anti-HIV activity in vitro

Antiviral research, 1991-10, Vol.16 (3), p.267-279

1991

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Association of Integrase, Matrix, and Reverse Transcriptase Antigens of Human Immunodeficiency Virus Type 1 with Viral Nucleic Acids Following Acute Infection

Structure-Based Design of HIV Protease Inhibitors: Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors

Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant: Lead Identification and SAR of 3- and 4-Substituted Derivatives

A Drug Resistance Mutation in the Inhibitor Binding Pocket of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Impairs DNA Synthesis and RNA Degradation

A recombinant ribonuclease H domain of HIV-1 reverse transcriptase that is enzymatically active

Functional characterization of RNA-dependent DNA polymerase and RNase H activities of a recombinant HIV reverse transcriptase

Oxazolidinones: a new class of antibacterials

(−)-6-Chloro-2-[(1-furo[2,3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a New Broad Spectrum HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor

Steady-state kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-87201E

Pyrimidine Thioethers: A Novel Class of HIV-1 Reverse Transcriptase Inhibitors with Activity Against BHAP-Resistant HIV

Treatment of human immunodeficiency virus type 1 (HIV-1)-infected cells with combinations of HIV-1-specific inhibitors results in a different resistance pattern than does treatment with single-drug therapy

Kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-88204E

Targeting Delavirdine/Atevirdine Resistant HIV-1: Identification of (Alkylamino)piperidine-Containing Bis(heteroaryl)piperazines as Broad Spectrum HIV-1 Reverse Transcriptase Inhibitors

The binding of a novel bisheteroarylpiperazine mediates inhibition of human immunodeficiency virus type 1 reverse transcriptase

Loss of Platelet-Derived Growth Factor-Stimulated Phospholipase Activity in NIH-3T3 Cells Expressing the EJ-ras Oncogene

Characterization of the p68/p58 Heterodimer of Human Immunodeficiency Virus Type 2 Reverse Transcriptase

The Differential Processing of Homodimers of Reverse Transcriptases from Human Immunodeficiency Viruses Type 1 and 2 Is a Consequence of the Distinct Specificities of the Viral Proteases

Inhibition of Human Immunodeficiency Virus Type 1 Replication In Vitro by the Bisheteroarylpiperzine Atevirdine (U-87201E) in Combination with Zidovudine or Didanosine

An active recombinant p15 RNase H domain is functionally distinct from the RNase H domain associated with human immunodeficiency virus type 1 reverse transcriptase

Escherichia coli expression, purification, and biological activity of a truncated soluble CD4

Reduced Hormone-Stimulated Adenylate Cyclase Activity in NIH-3T3 Cells Expressing the EJ Human Bladder ras Oncogene

Denaturation/refolding of purified recombinant HIV reverse transcriptase yields monomeric enzyme with high enzymatic activity

Effects of a soluble CD4 and CD4-Pseudomonas exotoxn A chimeric protein on human peripheral blood lymphocytes : lymphocyte activation and anti-HIV activity in vitro

Expression and characterization of chimeric rDNA proteins engineered for purification and enzymatic cleavage

Effects of a soluble CD4 and CD4- Pseudomonas exotoxin A chimeric protein on human peripheral blood lymphocytes: Lymphocyte activation and anti-HIV activity in vitro

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