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N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1

The Journal of experimental medicine, 2018-10, Vol.215 (10), p.2600-2616

2018

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Differential and overlapping targets of the transcriptional regulators NRF1, NRF2, and NRF3 in human cells

The Journal of biological chemistry, 2019-11, Vol.294 (48), p.18131-18149

2019

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Prolonged Cadmium Exposure and Osteoclastogenesis: A Mechanistic Mouse and in Vitro Study

Environmental health perspectives, 2024-06, Vol.132 (6), p.67009

2024

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Nuclear Factor Erythroid-2 Like 1 (NFE2L1): Structure, function and regulation

Gene, 2016-06, Vol.584 (1), p.17-25

2016

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Mitochondrial biogenesis and clearance: a balancing act

The FEBS journal, 2017-01, Vol.284 (2), p.183-195

2017

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Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance

Nature communications, 2021-09, Vol.12 (1), p.5270-15, Article 5270

2021

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Ferroptosis regulation by the NGLY1/NFE2L1 pathway

Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (11), p.e2118646119-e2118646119

2022

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Protective Effects of Hepatocyte Stress Defenders, Nrf1 and Nrf2, against MASLD Progression

International journal of molecular sciences, 2024-08, Vol.25 (15), p.8046

2024

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Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

The Journal of cell biology, 2024-06, Vol.223 (6)

2024

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Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation

Molecular cell, 2024-08, Vol.84 (16), p.3115-3127.e11

2024

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The multifaceted functions of NFE2L1 in metabolism and associated disorders

Life sciences (1973), 2024-09, Vol.352, p.122906, Article 122906

2024

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Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop

Molecular cell, 2010-10, Vol.40 (1), p.147-158

2010

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NF-E2-Related Factor 1 (Nrf1) Serves as a Novel Regulator of Hepatic Lipid Metabolism through Regulation of the Lipin1 and PGC-1β Genes

Molecular and Cellular Biology, 2012-07, Vol.32 (14), p.2760-2770

2012

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Loss of Nrf1 rather than Nrf2 leads to inflammatory accumulation of lipids and reactive oxygen species in human hepatoma cells, which is alleviated by 2-bromopalmitate

Biochimica et biophysica acta. Molecular cell research, 2024-02, Vol.1871 (2), p.119644-119644, Article 119644

2024

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Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

Nature medicine, 2018-03, Vol.24 (3), p.292-303

2018

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Pro-renin receptor suppresses mitochondrial biogenesis and function via AMPK/SIRT-1/ PGC-1α pathway in diabetic kidney

PloS one, 2019-12, Vol.14 (12), p.e0225728-e0225728

2019

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Long-isoform NRF1 protects against arsenic cytotoxicity in mouse bone marrow-derived mesenchymal stem cells by suppressing mitochondrial ROS and facilitating arsenic efflux

Toxicology and applied pharmacology, 2020-11, Vol.407, p.115251, Article 115251

2020

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EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer

The EMBO journal, 2015-12, Vol.34 (23), p.2953-2970

2015

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Estrogenic control of mitochondrial function and biogenesis

Journal of cellular biochemistry, 2008-12, Vol.105 (6), p.1342-1351

Klinge, Carolyn M.

2008

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Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism

Autophagy, 2019-01, Vol.15 (1), p.58-77

2019

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Nrf1 Reduces COX-2 Expression and Maintains Cellular Homeostasis After Cerebral Ischemia/Reperfusion By Targeting IL-6/TNF-α Protein Production

Journal of neuroimmune pharmacology, 2024-08, Vol.19 (1), p.41, Article 41

2024

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A novel nonsense variant in the NFE2L1 transcription factor in a patient with developmental delay, hypotonia, genital anomalies, and failure to thrive

Human mutation, 2022-04, Vol.43 (4), p.471-476

2022

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NRF1 and NRF2 mRNA and Protein Expression Decrease Early during Melanoma Carcinogenesis: An Insight into Survival and MicroRNAs

Oxidative medicine and cellular longevity, 2019, Vol.2019 (2019), p.1-15

2019

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T-2 toxin upregulates the expression of human cytochrome P450 1A1 (CYP1A1) by enhancing NRF1 and Sp1 interaction

Toxicology letters, 2019-10, Vol.315, p.77-86

2019

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Nfe2l1 deficiency mitigates streptozotocin-induced pancreatic β-cell destruction and development of diabetes in male mice

Food and chemical toxicology, 2021-12, Vol.158, p.112633-112633, Article 112633

2021

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N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1

Differential and overlapping targets of the transcriptional regulators NRF1, NRF2, and NRF3 in human cells

Prolonged Cadmium Exposure and Osteoclastogenesis: A Mechanistic Mouse and in Vitro Study

Nuclear Factor Erythroid-2 Like 1 (NFE2L1): Structure, function and regulation

Mitochondrial biogenesis and clearance: a balancing act

Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance

Ferroptosis regulation by the NGLY1/NFE2L1 pathway

Protective Effects of Hepatocyte Stress Defenders, Nrf1 and Nrf2, against MASLD Progression

Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation

The multifaceted functions of NFE2L1 in metabolism and associated disorders

Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop

NF-E2-Related Factor 1 (Nrf1) Serves as a Novel Regulator of Hepatic Lipid Metabolism through Regulation of the Lipin1 and PGC-1β Genes

Loss of Nrf1 rather than Nrf2 leads to inflammatory accumulation of lipids and reactive oxygen species in human hepatoma cells, which is alleviated by 2-bromopalmitate

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

Pro-renin receptor suppresses mitochondrial biogenesis and function via AMPK/SIRT-1/ PGC-1α pathway in diabetic kidney

Long-isoform NRF1 protects against arsenic cytotoxicity in mouse bone marrow-derived mesenchymal stem cells by suppressing mitochondrial ROS and facilitating arsenic efflux

EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer

Estrogenic control of mitochondrial function and biogenesis

Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism

Nrf1 Reduces COX-2 Expression and Maintains Cellular Homeostasis After Cerebral Ischemia/Reperfusion By Targeting IL-6/TNF-α Protein Production

A novel nonsense variant in the NFE2L1 transcription factor in a patient with developmental delay, hypotonia, genital anomalies, and failure to thrive

NRF1 and NRF2 mRNA and Protein Expression Decrease Early during Melanoma Carcinogenesis: An Insight into Survival and MicroRNAs

T-2 toxin upregulates the expression of human cytochrome P450 1A1 (CYP1A1) by enhancing NRF1 and Sp1 interaction

Nfe2l1 deficiency mitigates streptozotocin-induced pancreatic β-cell destruction and development of diabetes in male mice

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