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(−)-Rhazinilam and the diphenylpyridazinone NSC 613241: Two compounds inducing the formation of morphologically similar tubulin spirals but binding apparently to two distinct sites on tubulin

Archives of biochemistry and biophysics, 2016-08, Vol.604, p.63-73

2016

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Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors

European journal of medicinal chemistry, 2021-02, Vol.212, p.113122, Article 113122

2021

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Total Synthesis of Potent Antitumor Macrolide (-)-Zampanolide: An Oxidative Intramolecular Cyclization-Based Strategy

European journal of organic chemistry, 2012-08, Vol.2012 (22), p.4130-4139

2012

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Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity

Bioorganic & medicinal chemistry letters, 2013-08, Vol.23 (16), p.4669-4673

2013

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New Arylthioindoles and Related Bioisosteres at the Sulfur Bridging Group. 4. Synthesis, Tubulin Polymerization, Cell Growth Inhibition, and Molecular Modeling Studies

Journal of medicinal chemistry, 2009-12, Vol.52 (23), p.7512-7527

2009

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Interactions of Halichondrin B and Eribulin with Tubulin

Journal of chemical information and modeling, 2011-06, Vol.51 (6), p.1393-1404

2011

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Enantioselective Synthesis of (+)-Chamaecypanone C: A Novel Microtubule Inhibitor

Angewandte Chemie (International ed.), 2009-01, Vol.48 (8), p.1494-1497

2009

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Comparison of the Activities of the Truncated Halichondrin B Analog NSC 707389 (E7389) with Those of the Parent Compound and a Proposed Binding Site on Tubulin

Molecular pharmacology, 2006-12, Vol.70 (6), p.1866-1875

2006

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Laulimalide and Paclitaxel: A Comparison of Their Effects on Tubulin Assembly and Their Synergistic Action When Present Simultaneously

Molecular pharmacology, 2004-07, Vol.66 (1), p.113-121

2004

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Actin is the primary cellular receptor of bistramide A

Nature chemical biology, 2005-12, Vol.1 (7), p.383-388

2005

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(−)-RHAZINILAM AND THE DIPHENYLPYRIDAZINONE NSC 613241: TWO COMPOUNDS INDUCING THE FORMATION OF MORPHOLOGICALLY SIMILAR TUBULIN SPIRALS BUT BINDING APPARENTLY TO TWO DISTINCT SITES ON TUBULIN1,2

Archives of biochemistry and biophysics, 2016-06, Vol.604, p.63-73

2016

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Intracellular Activation and Deactivation of Tasidotin, an Analog of Dolastatin 15: Correlation with Cytotoxicity

Molecular pharmacology, 2009-01, Vol.75 (1), p.218-226

2009

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Corrigendum to “The interaction of spongistatin 1 with tubulin” [Arch. Biochem. Biophys. 727 (2022) 109296 (7 pages)]

Archives of biochemistry and biophysics, 2022-11, Vol.730, p.109412-109412, Article 109412

2022

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Identification of pyrrolo[3′,4’:3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas

European journal of medicinal chemistry, 2023-06, Vol.254, p.115372-115372, Article 115372

2023

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Interaction of a Cyclostreptin Analogue with the Microtubule Taxoid Site: The Covalent Reaction Rapidly Follows Binding

Journal of natural products (Washington, D.C.), 2008-03, Vol.71 (3), p.370-374

2008

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Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas

European journal of medicinal chemistry, 2022-12, Vol.243, p.114744-114744, Article 114744

2022

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(â)-Doliculide, a New Macrocyclic Depsipeptide Enhancer of Actin Assembly

The Journal of biological chemistry, 2002-08, Vol.277 (35), p.32165-32171

2002

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Abstract 6244: Design, synthesis, and structure-activity relationships of substituted pyrido[3,2- d ]pyrimidines as microtubule targeting agents and anti-cancer agents

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.6244-6244

2023

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Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor

Journal of medicinal chemistry, 2022-12, Vol.65 (23), p.15805-15818

2022

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Novel pyrazolo4,3-dpyrimidine microtubule targeting agents (MTAs): Synthesis, structure-activity relationship, in vitro and in vivo evaluation as antitumor agents

Bioorganic & medicinal chemistry letters, 2021-06, Vol.41, p.127923

2021

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RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo

European journal of medicinal chemistry, 2023-01, Vol.246, p.114997-114997, Article 114997

2023

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Structure Guided Design, Synthesis, and Biological Evaluation of Oxetane-Containing Indole Analogues

Bioorganic & medicinal chemistry, 2023-09, Vol.92, p.117400, Article 117400

2023

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Total synthesis and biological evaluation of ustiloxin natural products and two analogs

Bioorganic & medicinal chemistry letters, 2006-09, Vol.16 (18), p.4804-4807

2006

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Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors

Computational biology and chemistry, 2019-06, Vol.80, p.512-523

2019

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A new anti-tubulin agent containing the benzo[ b]thiophene ring system

Bioorganic & medicinal chemistry letters, 1999-04, Vol.9 (8), p.1081-1086

1999

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(−)-Rhazinilam and the diphenylpyridazinone NSC 613241: Two compounds inducing the formation of morphologically similar tubulin spirals but binding apparently to two distinct sites on tubulin

Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors

Total Synthesis of Potent Antitumor Macrolide (-)-Zampanolide: An Oxidative Intramolecular Cyclization-Based Strategy

Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity

New Arylthioindoles and Related Bioisosteres at the Sulfur Bridging Group. 4. Synthesis, Tubulin Polymerization, Cell Growth Inhibition, and Molecular Modeling Studies

Interactions of Halichondrin B and Eribulin with Tubulin

Enantioselective Synthesis of (+)-Chamaecypanone C: A Novel Microtubule Inhibitor

Comparison of the Activities of the Truncated Halichondrin B Analog NSC 707389 (E7389) with Those of the Parent Compound and a Proposed Binding Site on Tubulin

Laulimalide and Paclitaxel: A Comparison of Their Effects on Tubulin Assembly and Their Synergistic Action When Present Simultaneously

Actin is the primary cellular receptor of bistramide A

(−)-RHAZINILAM AND THE DIPHENYLPYRIDAZINONE NSC 613241: TWO COMPOUNDS INDUCING THE FORMATION OF MORPHOLOGICALLY SIMILAR TUBULIN SPIRALS BUT BINDING APPARENTLY TO TWO DISTINCT SITES ON TUBULIN1,2

Intracellular Activation and Deactivation of Tasidotin, an Analog of Dolastatin 15: Correlation with Cytotoxicity

Corrigendum to “The interaction of spongistatin 1 with tubulin” [Arch. Biochem. Biophys. 727 (2022) 109296 (7 pages)]

Identification of pyrrolo[3′,4’:3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas

Interaction of a Cyclostreptin Analogue with the Microtubule Taxoid Site: The Covalent Reaction Rapidly Follows Binding

Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas

(â)-Doliculide, a New Macrocyclic Depsipeptide Enhancer of Actin Assembly

Abstract 6244: Design, synthesis, and structure-activity relationships of substituted pyrido[3,2- d ]pyrimidines as microtubule targeting agents and anti-cancer agents

Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor

Novel pyrazolo4,3-dpyrimidine microtubule targeting agents (MTAs): Synthesis, structure-activity relationship, in vitro and in vivo evaluation as antitumor agents

RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo

Structure Guided Design, Synthesis, and Biological Evaluation of Oxetane-Containing Indole Analogues

Total synthesis and biological evaluation of ustiloxin natural products and two analogs

Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors

A new anti-tubulin agent containing the benzo[ b]thiophene ring system

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