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Synthesis and Characterization of Thiophosphoramidate Morpholino Oligonucleotides and Chimeras

Journal of the American Chemical Society, 2020-09, Vol.142 (38), p.16240-16253

2020

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Synthesis and Biophysical Studies of High-Affinity Morpholino Oligomers Containing G‑Clamp Analogs

Journal of organic chemistry, 2023-11, Vol.88 (21), p.15168-15175

2023

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Tightly linked morpholino-nucleoside chimeras: new, compact cationic oligonucleotide analogues

Organic & biomolecular chemistry, 2021-10, Vol.19 (4), p.8711-8721

2021

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Molybdenum disulfide field-effect transistor biosensor for ultrasensitive detection of DNA by employing morpholino as probe

Biosensors & bioelectronics, 2018-07, Vol.110, p.71-77

2018

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Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function

Molecules (Basel, Switzerland), 2020-04, Vol.25 (9), p.2078

2020

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Structural insights into the morpholino nucleic acid/RNA duplex using the new XNA builder Ducque in a molecular modeling pipeline

Nucleic acids research, 2024-04, Vol.52 (6), p.2836-2847

2024

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Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry

Journal of the American Chemical Society, 2016-12, Vol.138 (48), p.15663-15672

2016

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C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity

Organic & biomolecular chemistry, 2023-02, Vol.21 (6), p.1242-1253

2023

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Sequencing of Phosphorodiamidate Morpholino Oligomers by Hydrophilic Interaction Chromatography Coupled to Tandem Mass Spectrometry

Journal of the American Society for Mass Spectrometry, 2024-10, Vol.35 (10), p.2490-2498

2024

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Organocatalytic Ring-Opening Polymerization of Morpholinones: New Strategies to Functionalized Polyesters

Journal of the American Chemical Society, 2014-07, Vol.136 (26), p.9252-9255

2014

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Exploring site‐specific activation of bis‐N,N’‐dialkylaminophosphordiamidites and the synthesis of morpholinophosphoramidate oligonucleotides

FEBS letters, 2019-07, Vol.593 (13), p.1459-1467

2019

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Drug-free macromolecular therapeutics: Impact of structure on induction of apoptosis in Raji B cells

Journal of controlled release, 2017-10, Vol.263, p.139-150

2017

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Inhibition of Bacterial Growth by Peptide-Conjugated Morpholino Oligomers

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1565, p.115

2017

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Development of 2-Morpholino-N-hydroxybenzamides as anti-proliferative PC-PLC inhibitors

Bioorganic chemistry, 2021-09, Vol.114, p.105152-105152, Article 105152

2021

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Synthesis of triazole-linked morpholino oligonucleotides via Cu(I) catalysed cycloaddition

Organic & biomolecular chemistry, 2016-03, Vol.14 (11), p.3112-3119

2016

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Structural elucidation of foldamers with no long range conformational order

Chemical communications (Cambridge, England), 2014-09, Vol.50 (70), p.10090-10093

2014

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Combined effect of a peptide–morpholino oligonucleotide conjugate and a cell-penetrating peptide as an antibiotic

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (21), p.8686-8689

2013

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Oligodeoxynucleotides containing 2′-amino-LNA nucleotides as constrained morpholino phosphoramidate and phosphorodiamidate monomers

Bioorganic & medicinal chemistry letters, 2017-07, Vol.27 (14), p.3173-3176

2017

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Design, Synthesis and Molecular Modeling Study of Conjugates of ADP and Morpholino Nucleosides as A Novel Class of Inhibitors of PARP-1, PARP-2 and PARP-3

International journal of molecular sciences, 2019-12, Vol.21 (1), p.214

2019

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The morpholino molecular beacon for specific RNA visualization in vivo

Chemical communications (Cambridge, England), 2016-01, Vol.52 (15), p.3191-3194

2016

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Morpholino-functionalized phosphorus dendrimers for precision regenerative medicine: osteogenic differentiation of mesenchymal stem cells

Nanoscale, 2019-10, Vol.11 (37), p.1723-17234

2019

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Amphiphilic lipopeptide significantly enhances uptake of charge-neutral splice switching morpholino oligonucleotide in spinal muscular atrophy patient-derived fibroblasts

International journal of pharmaceutics, 2017-10, Vol.532 (1), p.21-28

2017

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Enhancing the speed of morpholino-DNA biosensor by electrokinetic concentration of DNA in a microfluidic chip

Biosensors & bioelectronics, 2015-10, Vol.72, p.87-94

2015

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In Vitro Evaluation of Antisense-Mediated Exon Inclusion for Spinal Muscular Atrophy

Methods in molecular biology (Clifton, N.J.), 2018, Vol.1828, p.439

2018

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Synthesis of Chlorophosphoramidate Monomer Morpholinos and PMOs

Current protocols, 2023-02, Vol.3 (2), p.e686-n/a

2023

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Synthesis and Characterization of Thiophosphoramidate Morpholino Oligonucleotides and Chimeras

Synthesis and Biophysical Studies of High-Affinity Morpholino Oligomers Containing G‑Clamp Analogs

Tightly linked morpholino-nucleoside chimeras: new, compact cationic oligonucleotide analogues

Molybdenum disulfide field-effect transistor biosensor for ultrasensitive detection of DNA by employing morpholino as probe

Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function

Structural insights into the morpholino nucleic acid/RNA duplex using the new XNA builder Ducque in a molecular modeling pipeline

Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry

C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity

Sequencing of Phosphorodiamidate Morpholino Oligomers by Hydrophilic Interaction Chromatography Coupled to Tandem Mass Spectrometry

Organocatalytic Ring-Opening Polymerization of Morpholinones: New Strategies to Functionalized Polyesters

Exploring site‐specific activation of bis‐N,N’‐dialkylaminophosphordiamidites and the synthesis of morpholinophosphoramidate oligonucleotides

Drug-free macromolecular therapeutics: Impact of structure on induction of apoptosis in Raji B cells

Inhibition of Bacterial Growth by Peptide-Conjugated Morpholino Oligomers

Development of 2-Morpholino-N-hydroxybenzamides as anti-proliferative PC-PLC inhibitors

Synthesis of triazole-linked morpholino oligonucleotides via Cu(I) catalysed cycloaddition

Structural elucidation of foldamers with no long range conformational order

Combined effect of a peptide–morpholino oligonucleotide conjugate and a cell-penetrating peptide as an antibiotic

Oligodeoxynucleotides containing 2′-amino-LNA nucleotides as constrained morpholino phosphoramidate and phosphorodiamidate monomers

Design, Synthesis and Molecular Modeling Study of Conjugates of ADP and Morpholino Nucleosides as A Novel Class of Inhibitors of PARP-1, PARP-2 and PARP-3

The morpholino molecular beacon for specific RNA visualization in vivo

Morpholino-functionalized phosphorus dendrimers for precision regenerative medicine: osteogenic differentiation of mesenchymal stem cells

Amphiphilic lipopeptide significantly enhances uptake of charge-neutral splice switching morpholino oligonucleotide in spinal muscular atrophy patient-derived fibroblasts

Enhancing the speed of morpholino-DNA biosensor by electrokinetic concentration of DNA in a microfluidic chip

In Vitro Evaluation of Antisense-Mediated Exon Inclusion for Spinal Muscular Atrophy

Synthesis of Chlorophosphoramidate Monomer Morpholinos and PMOs

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