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Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): our past twenty years

Acta pharmaceutica Sinica. B, 2020-06, Vol.10 (6), p.961-978

2020

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Structural-Based Optimizations of the Marine-Originated Meridianin C as Glucose Uptake Agents by Inhibiting GSK-3β

Marine drugs, 2021-03, Vol.19 (3), p.149

2021

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Ligand-based substituent-anchoring design of selective receptor-interacting protein kinase 1 necroptosis inhibitors for ulcerative colitis therapy

Acta pharmaceutica Sinica. B, 2021-10, Vol.11 (10), p.3193-3205

2021

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Structure-based optimizations of a necroptosis inhibitor (SZM594) as novel protective agents of acute lung injury

Chinese chemical letters, 2022-05, Vol.33 (5), p.2545-2549

2022

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Dietary Phytochemicals as Potential Chemopreventive Agents against Tobacco-Induced Lung Carcinogenesis

Nutrients, 2023-01, Vol.15 (3), p.491

2023

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Small-Molecule Inhibitors of Necroptosis: Current Status and Perspectives

Journal of medicinal chemistry, 2020-02, Vol.63 (4), p.1490-1510

2020

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A Systematic Review and Meta-analysis of the Effects of Topical Tranexamic Acid versus Topical Vasoconstrictors on the Management of Epistaxis

Current pharmaceutical design, 2023-01, Vol.29 (19), p.1497

2023

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Radiosensitization of human pancreatic cancer by piperlongumine analogues

Chinese chemical letters, 2021-03, Vol.32 (3), p.1197-1201

2021

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Updated research and applications of small molecule inhibitors of Keap1-Nrf2 protein-protein interaction: a review

Current medicinal chemistry, 2014, Vol.21 (16), p.1861

2014

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Fragment-based discovery of sulfur-containing diarylbenzopyrimidines as novel nonnucleoside reverse transcriptase inhibitors

Chinese chemical letters, 2020-03, Vol.31 (3), p.764-768

2020

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Design of Biphenyl-Substituted Diarylpyrimidines with a Cyanomethyl Linker as HIV-1 NNRTIs via a Molecular Hybridization Strategy

Molecules (Basel, Switzerland), 2020-02, Vol.25 (5), p.1050

2020

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A potent phosphodiester Keap1-Nrf2 protein-protein interaction inhibitor as the efficient treatment of Alzheimer's disease

Redox biology, 2023-08, Vol.64, p.102793-102793, Article 102793

2023

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Design, synthesis and anti-necroptosis activity of fused heterocyclic MLKL inhibitors

Bioorganic & medicinal chemistry, 2024-03, Vol.102, p.117659-117659, Article 117659

2024

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Profiling of small-molecule necroptosis inhibitors based on the subpockets of kinase-ligand interactions

Medicinal research reviews, 2023-11, Vol.43 (6), p.1974-2024

2023

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Improving the positional adaptability: structure-based design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

Acta pharmaceutica Sinica. B, 2020-02, Vol.10 (2), p.344-357

2020

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Front Cover Image, Volume 43, Issue 6

Medicinal research reviews, 2023-11, Vol.43 (6)

2023

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Discovery of a Novel Benzimidazole Necroptosis Inhibitor from an In-House Compound Library

Pharmaceutical fronts, 2024-07

2024

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Methodology of drug screening and target identification for new necroptosis inhibitors

Journal of pharmaceutical analysis, 2019-04, Vol.9 (2), p.71-76

2019

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A combined nanotherapeutic approach targeting farnesoid X receptor, ferroptosis, and fibrosis for nonalcoholic steatohepatitis treatment

Acta pharmaceutica Sinica. B, 2024-05, Vol.14 (5), p.2228-2246

2024

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Transcription factor NRF2 as a promising therapeutic target for Alzheimer’s disease

Free radical biology & medicine, 2020-11, Vol.159, p.87-102

2020

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Structure–activity relationship and antitumor activity of thio-benzodiazepines as p53–MDM2 protein–protein interaction inhibitors

European journal of medicinal chemistry, 2012-10, Vol.56, p.10-16

2012

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Druggability modification strategies of the diarylpyrimidine‐type non‐nucleoside reverse transcriptase inhibitors

Medicinal research reviews, 2021-05, Vol.41 (3), p.1255-1290

2021

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Small molecule-drug conjugates: A novel strategy for cancer-targeted treatment

European journal of medicinal chemistry, 2019-02, Vol.163, p.883-895

2019

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Synthesis and biological evaluation of thio-benzodiazepines as novel small molecule inhibitors of the p53–MDM2 protein–protein interaction

European journal of medicinal chemistry, 2011-11, Vol.46 (11), p.5654-5661

2011

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Design, synthesis and structure–activity relationships of new triazole derivatives containing N-substituted phenoxypropylamino side chains

European journal of medicinal chemistry, 2012-07, Vol.53, p.292-299

2012

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Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): our past twenty years

Structural-Based Optimizations of the Marine-Originated Meridianin C as Glucose Uptake Agents by Inhibiting GSK-3β

Ligand-based substituent-anchoring design of selective receptor-interacting protein kinase 1 necroptosis inhibitors for ulcerative colitis therapy

Structure-based optimizations of a necroptosis inhibitor (SZM594) as novel protective agents of acute lung injury

Dietary Phytochemicals as Potential Chemopreventive Agents against Tobacco-Induced Lung Carcinogenesis

Small-Molecule Inhibitors of Necroptosis: Current Status and Perspectives

A Systematic Review and Meta-analysis of the Effects of Topical Tranexamic Acid versus Topical Vasoconstrictors on the Management of Epistaxis

Radiosensitization of human pancreatic cancer by piperlongumine analogues

Updated research and applications of small molecule inhibitors of Keap1-Nrf2 protein-protein interaction: a review

Fragment-based discovery of sulfur-containing diarylbenzopyrimidines as novel nonnucleoside reverse transcriptase inhibitors

Design of Biphenyl-Substituted Diarylpyrimidines with a Cyanomethyl Linker as HIV-1 NNRTIs via a Molecular Hybridization Strategy

A potent phosphodiester Keap1-Nrf2 protein-protein interaction inhibitor as the efficient treatment of Alzheimer's disease

Design, synthesis and anti-necroptosis activity of fused heterocyclic MLKL inhibitors

Profiling of small-molecule necroptosis inhibitors based on the subpockets of kinase-ligand interactions

Improving the positional adaptability: structure-based design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

Front Cover Image, Volume 43, Issue 6

Discovery of a Novel Benzimidazole Necroptosis Inhibitor from an In-House Compound Library

Methodology of drug screening and target identification for new necroptosis inhibitors

A combined nanotherapeutic approach targeting farnesoid X receptor, ferroptosis, and fibrosis for nonalcoholic steatohepatitis treatment

Transcription factor NRF2 as a promising therapeutic target for Alzheimer’s disease

Structure–activity relationship and antitumor activity of thio-benzodiazepines as p53–MDM2 protein–protein interaction inhibitors

Druggability modification strategies of the diarylpyrimidine‐type non‐nucleoside reverse transcriptase inhibitors

Small molecule-drug conjugates: A novel strategy for cancer-targeted treatment

Synthesis and biological evaluation of thio-benzodiazepines as novel small molecule inhibitors of the p53–MDM2 protein–protein interaction

Design, synthesis and structure–activity relationships of new triazole derivatives containing N-substituted phenoxypropylamino side chains

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