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The Opportunities and Challenges of Peroxisome Proliferator-Activated Receptors Ligands in Clinical Drug Discovery and Development

International journal of molecular sciences, 2018-07, Vol.19 (8), p.2189

2018

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The Role of PPAR and Its Cross-Talk with CAR and LXR in Obesity and Atherosclerosis

International journal of molecular sciences, 2018-04, Vol.19 (4), p.1260

2018

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Celastrol inhibits store operated calcium entry and suppresses psoriasis

Frontiers in pharmacology, 2023-02, Vol.14, p.1111798-1111798

2023

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Melatonin Attenuates Dextran Sodium Sulfate Induced Colitis in Obese Mice

Pharmaceuticals (Basel, Switzerland), 2021-08, Vol.14 (8), p.822

2021

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Activation of human stearoyl-coenzyme A desaturase 1 contributes to the lipogenic effect of PXR in HepG2 cells

PloS one, 2013-07, Vol.8 (7), p.e67959-e67959

2013

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Mdb1, a fission yeast homolog of human MDC1, modulates DNA damage response and mitotic spindle function

PloS one, 2014-05, Vol.9 (5), p.e97028

2014

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Therapeutic potential of melatonin in colorectal cancer: Focus on lipid metabolism and gut microbiota

Biochimica et biophysica acta. Molecular basis of disease, 2022-01, Vol.1868 (1), p.166281-166281, Article 166281

2022

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Cytotoxicity and apoptosis induced by a new podophyllotoxin glucoside in human hepatoma (HepG2) cells

Canadian journal of physiology and pharmacology, 2010-04, Vol.88 (4), p.472-479

2010

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DBZ is a putative PPARγ agonist that prevents high fat diet-induced obesity, insulin resistance and gut dysbiosis

Biochimica et biophysica acta. General subjects, 2017-11, Vol.1861 (11), p.2690-2701

2017

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Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

Gastroenterology (New York, N.Y. 1943), 2008-02, Vol.134 (2), p.556-567.e1

2008

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The CAR agonist TCPOBOP inhibits lipogenesis and promotes fibrosis in the mammary gland of adolescent female mice

Toxicology letters, 2018-06, Vol.290, p.29-35

2018

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Genotoxic stress causes the accumulation of DNA‐dependent protein kinase catalytic subunit phosphorylated at serine 2056 at nuclear speckles and alters pre‐mRNA alternative splicing

FEBS open bio, 2019-02, Vol.9 (2), p.304-314

2019

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Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase

The Journal of biological chemistry, 2015-01, Vol.290 (1), p.241-241

2015

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CHIP functions an E3 ubiquitin ligase of Runx1

Biochemical and biophysical research communications, 2009-08, Vol.386 (1), p.242-246

2009

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HPRT1 activity loss is associated with resistance to thiopurine in ALL

Oncotarget, 2018-01, Vol.9 (2), p.2268-2278

2018

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p15RS Attenuates Wnt/β-Catenin Signaling by Disrupting β-Catenin·TCF4 Interaction

The Journal of biological chemistry, 2010-11, Vol.285 (45), p.34621-34631

2010

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Mature adipocytes observed to undergo reproliferation and polyploidy

FEBS open bio, 2017-05, Vol.7 (5), p.652-658

2017

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ROR[alpha] inhibits adipocyte-conditioned medium-induced colorectal cancer cell proliferation and migration and chick embryo chorioallantoic membrane angiopoiesis

American Journal of Physiology: Cell Physiology, 2015-03, Vol.308 (5), p.C385

2015

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Functional crosstalk of CAR-LXR and ROR-LXR in drug metabolism and lipid metabolism: Development of Novel Therapeutic Strategy by Regulating the Nuclear Hormone Receptors

Advanced drug delivery reviews, 2010, Vol.62 (13), p.1316-1321

2010

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Biology of PXR: role in drug-hormone interactions

EXCLI journal, 2014-01, Vol.13, p.728-739

2014

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A Functional Cross-Talk between Liver X Receptor-α and Constitutive Androstane Receptor Links Lipogenesis and Xenobiotic ResponsesS

Molecular pharmacology, 2010-10, Vol.78 (4), p.666-674

2010

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Activation of LXR Increases Acetaminophen Clearance and Prevents Its Toxicity

Hepatology (Baltimore, Md.), 2011-12, Vol.54 (6), p.2208-2217

2011

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Dishevelled-DEP domain interacting protein (DDIP) inhibits Wnt signaling by promoting TCF4 degradation and disrupting the TCF4/b-catenin complex

Cellular signalling, 2010-11, Vol.22 (11), p.1753-1760

2010

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Mdb1, a Fission Yeast Homolog of Human MDC1, Modulates DNA Damage Response and Mitotic Spindle Function: e97028

PloS one, 2014-05, Vol.9 (5)

2014

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p15RS attenuates Wnt/{beta}-catenin signaling by disrupting {beta}-catenin·TCF4 Interaction

The Journal of biological chemistry, 2010-11, Vol.285 (45), p.34621

2010

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The Opportunities and Challenges of Peroxisome Proliferator-Activated Receptors Ligands in Clinical Drug Discovery and Development

The Role of PPAR and Its Cross-Talk with CAR and LXR in Obesity and Atherosclerosis

Celastrol inhibits store operated calcium entry and suppresses psoriasis

Melatonin Attenuates Dextran Sodium Sulfate Induced Colitis in Obese Mice

Activation of human stearoyl-coenzyme A desaturase 1 contributes to the lipogenic effect of PXR in HepG2 cells

Mdb1, a fission yeast homolog of human MDC1, modulates DNA damage response and mitotic spindle function

Therapeutic potential of melatonin in colorectal cancer: Focus on lipid metabolism and gut microbiota

Cytotoxicity and apoptosis induced by a new podophyllotoxin glucoside in human hepatoma (HepG2) cells

DBZ is a putative PPARγ agonist that prevents high fat diet-induced obesity, insulin resistance and gut dysbiosis

Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

The CAR agonist TCPOBOP inhibits lipogenesis and promotes fibrosis in the mammary gland of adolescent female mice

Genotoxic stress causes the accumulation of DNA‐dependent protein kinase catalytic subunit phosphorylated at serine 2056 at nuclear speckles and alters pre‐mRNA alternative splicing

Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase

CHIP functions an E3 ubiquitin ligase of Runx1

HPRT1 activity loss is associated with resistance to thiopurine in ALL

p15RS Attenuates Wnt/β-Catenin Signaling by Disrupting β-Catenin·TCF4 Interaction

Mature adipocytes observed to undergo reproliferation and polyploidy

ROR[alpha] inhibits adipocyte-conditioned medium-induced colorectal cancer cell proliferation and migration and chick embryo chorioallantoic membrane angiopoiesis

Functional crosstalk of CAR-LXR and ROR-LXR in drug metabolism and lipid metabolism: Development of Novel Therapeutic Strategy by Regulating the Nuclear Hormone Receptors

Biology of PXR: role in drug-hormone interactions

A Functional Cross-Talk between Liver X Receptor-α and Constitutive Androstane Receptor Links Lipogenesis and Xenobiotic ResponsesS

Activation of LXR Increases Acetaminophen Clearance and Prevents Its Toxicity

Dishevelled-DEP domain interacting protein (DDIP) inhibits Wnt signaling by promoting TCF4 degradation and disrupting the TCF4/b-catenin complex

Mdb1, a Fission Yeast Homolog of Human MDC1, Modulates DNA Damage Response and Mitotic Spindle Function: e97028

p15RS attenuates Wnt/{beta}-catenin signaling by disrupting {beta}-catenin·TCF4 Interaction

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