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Activation of nemo-like kinase in diamond blackfan anemia suppresses early erythropoiesis by preventing mitochondrial biogenesis

The Journal of biological chemistry, 2024-08, Vol.300 (8), p.107542, Article 107542

2024

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Beyond mRNA: The role of non-coding RNAs in normal and aberrant hematopoiesis

Molecular genetics and metabolism, 2017-11, Vol.122 (3), p.28-38

2017

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Downregulation of SATB1 by miRNAs reduces megakaryocyte/erythroid progenitor expansion in preclinical models of Diamond–Blackfan anemia

Experimental hematology, 2022-07, Vol.111, p.66-78

2022

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Signaling Pathways That Regulate Normal and Aberrant Red Blood Cell Development

Genes, 2021-10, Vol.12 (10), p.1646

2021

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SATB1 Chromatin Loops Regulate Megakaryocyte/Erythroid Progenitor Expansion by Facilitating HSP70 and GATA1 Induction

Stem cells (Dayton, Ohio), 2023-06, Vol.41 (6), p.560-569

2023

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The active component of ginseng, ginsenoside Rb1, improves erythropoiesis in models of Diamond–Blackfan anemia by targeting Nemo-like kinase

The Journal of biological chemistry, 2021-09, Vol.297 (3), p.100988-100988, Article 100988

2021

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Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia

Scientific reports, 2018-03, Vol.8 (1), p.5165-11, Article 5165

2018

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MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-β pathways

Blood advances, 2019-09, Vol.3 (18), p.2751-2763

2019

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The Serine Threonine Kinase Inhibitor Ots-167 Improves Erythropoiesis through Suppression of Nlk Activity in Diamond Blackfan Anemia Models

Blood, 2021-11, Vol.138 (Supplement 1), p.2179-2179

2021

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SATB1 Regulates Chromatin Organization and HSP70 Expression in Early Erythropoiesis and Is Downregulated in Models of Diamond Blackfan Anemia

Blood, 2021-11, Vol.138 (Supplement 1), p.2189-2189

2021

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Nutritional Supplements, Ginseng and Leucine, Increase Erythropoiesis in Diamond Blackfan Anemia Models through Inhibition of Nemo-like Kinase

Blood, 2021-11, Vol.138 (Supplement 1), p.1129-1129

2021

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Genetic Modulators of Niclosamide Sensitivity and Resistance in Acute Myeloid Leukemia

Blood, 2020-11, Vol.136 (Supplement 1), p.29-29

2020

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Chromatin Organization By SATB1 Regulates HSP70 Induction in Early Erythropoiesis and Lost in Diamond Blackfan Anemia

Blood, 2018-11, Vol.132 (Supplement 1), p.2591-2591

2018

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SATB1 Regulates GATA1 Protein Expression in Early Hematopoiesis and Is Deregulated in Diamond Blackfan Anemia

Blood, 2020-11, Vol.136 (Supplement 1), p.3-3

2020

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Metformin Upregulates Mir-26a to Improve Erythropoiesis in Preclinical Models of Diamond Blackfan Anemia through Suppression of Nlk Expression

Blood, 2020-11, Vol.136 (Supplement 1), p.7-7

2020

Volltextzugriff (PDF)

3141 – GINSENOSIDE RB1 AND METFORMIN IMPROVES ERYTHROPOIESIS IN MODELS OF DIAMOND BLACKFAN ANEMIA BY TARGETING NEMO-LIKE KINASE

Experimental hematology, 2021-08, Vol.100, p.S110-S110

2021

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Nemo-like Kinase Hyper-Activated in Erythroid Progenitors in Models of Diamond Blackfan Anemia

Blood, 2017-12, Vol.130 (Suppl_1), p.78-78

2017

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MMP9 Inhibition Rescues the Erythroid Defect in RPS14-Deficient Del(5q) MDS Models

Blood, 2018-11, Vol.132 (Supplement 1), p.756-756

2018

Volltextzugriff (PDF)

3182 – PHARMACOLOGICAL INHIBITION OF NEMO-LIKE KINASE RESCUES MTOR-MEDIATED TRANSLATION AND ERYTHROPOIESIS IN PRE-CLINICAL MODELS OF DIAMOND BLACKFAN ANEMIA

Experimental hematology, 2019-08, Vol.76, p.e5-e6

2019

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Sorting Nexin 9 Differentiates Ligand‐Activated Smad3 from Smad2 for Nuclear Translocation and TGFβ Signaling

The FASEB journal, 2016-04, Vol.30 (S1)

2016

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Role of Mir-34 Upregulation in Disruption of c-Myc, c-Myb and NOTCH Signaling in Diamond-Blackfan Anemia

Blood, 2016-12, Vol.128 (22), p.3895-3895

2016

Volltextzugriff (PDF)

Pharmacological Inhibition of Nlk (Nemo-like Kinase) Rescues Erythropoietic Defects in Pre-Clinical Models of Diamond Blackfan Anemia

Blood, 2018-11, Vol.132 (Supplement 1), p.754-754

2018

Volltextzugriff (PDF)

Pharmacological Inhibition of Nemo-like Kinase Rescues mTOR-Mediated Translation and Primes Progenitors for Leucine-Stimulated Erythroid Expansion in Pre-Clinical Models of Diamond Blackfan Anemia

Blood, 2019-11, Vol.134 (Supplement_1), p.455-455

2019

Volltextzugriff (PDF)

Noncanonical TGF-β pathways, mTORC1 and Abl, in renal interstitial fibrogenesis

American journal of physiology. Renal physiology, 2010, Vol.67 (1)

2010

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Noncanonical TGF-[beta] pathways, mTORC1 and Abl, in renal interstitial fibrogenesis

American journal of physiology. Renal physiology, 2010-01, Vol.298 (1), p.F142

2010

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Activation of nemo-like kinase in diamond blackfan anemia suppresses early erythropoiesis by preventing mitochondrial biogenesis

Beyond mRNA: The role of non-coding RNAs in normal and aberrant hematopoiesis

Downregulation of SATB1 by miRNAs reduces megakaryocyte/erythroid progenitor expansion in preclinical models of Diamond–Blackfan anemia

Signaling Pathways That Regulate Normal and Aberrant Red Blood Cell Development

SATB1 Chromatin Loops Regulate Megakaryocyte/Erythroid Progenitor Expansion by Facilitating HSP70 and GATA1 Induction

The active component of ginseng, ginsenoside Rb1, improves erythropoiesis in models of Diamond–Blackfan anemia by targeting Nemo-like kinase

Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia

MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-β pathways

The Serine Threonine Kinase Inhibitor Ots-167 Improves Erythropoiesis through Suppression of Nlk Activity in Diamond Blackfan Anemia Models

SATB1 Regulates Chromatin Organization and HSP70 Expression in Early Erythropoiesis and Is Downregulated in Models of Diamond Blackfan Anemia

Nutritional Supplements, Ginseng and Leucine, Increase Erythropoiesis in Diamond Blackfan Anemia Models through Inhibition of Nemo-like Kinase

Genetic Modulators of Niclosamide Sensitivity and Resistance in Acute Myeloid Leukemia

Chromatin Organization By SATB1 Regulates HSP70 Induction in Early Erythropoiesis and Lost in Diamond Blackfan Anemia

SATB1 Regulates GATA1 Protein Expression in Early Hematopoiesis and Is Deregulated in Diamond Blackfan Anemia

Metformin Upregulates Mir-26a to Improve Erythropoiesis in Preclinical Models of Diamond Blackfan Anemia through Suppression of Nlk Expression

3141 – GINSENOSIDE RB1 AND METFORMIN IMPROVES ERYTHROPOIESIS IN MODELS OF DIAMOND BLACKFAN ANEMIA BY TARGETING NEMO-LIKE KINASE

Nemo-like Kinase Hyper-Activated in Erythroid Progenitors in Models of Diamond Blackfan Anemia

MMP9 Inhibition Rescues the Erythroid Defect in RPS14-Deficient Del(5q) MDS Models

3182 – PHARMACOLOGICAL INHIBITION OF NEMO-LIKE KINASE RESCUES MTOR-MEDIATED TRANSLATION AND ERYTHROPOIESIS IN PRE-CLINICAL MODELS OF DIAMOND BLACKFAN ANEMIA

Sorting Nexin 9 Differentiates Ligand‐Activated Smad3 from Smad2 for Nuclear Translocation and TGFβ Signaling

Role of Mir-34 Upregulation in Disruption of c-Myc, c-Myb and NOTCH Signaling in Diamond-Blackfan Anemia

Pharmacological Inhibition of Nlk (Nemo-like Kinase) Rescues Erythropoietic Defects in Pre-Clinical Models of Diamond Blackfan Anemia

Pharmacological Inhibition of Nemo-like Kinase Rescues mTOR-Mediated Translation and Primes Progenitors for Leucine-Stimulated Erythroid Expansion in Pre-Clinical Models of Diamond Blackfan Anemia

Noncanonical TGF-β pathways, mTORC1 and Abl, in renal interstitial fibrogenesis

Noncanonical TGF-[beta] pathways, mTORC1 and Abl, in renal interstitial fibrogenesis

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