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Tamoxifen Derivatives Alter Retromer-Dependent Endosomal Tubulation and Sorting to Block Retrograde Trafficking of Shiga Toxins

Toxins, 2021-06, Vol.13 (6), p.424

2021

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Inhibition of Ca2+ entry by capsazepine analog CIDD-99 prevents oral squamous carcinoma cell proliferation

Frontiers in physiology, 2022-09, Vol.13, p.969000-969000

2022

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Corrigendum to “Rational approach to drug discovery for human schistosomiasis” [Int. J. Parasitol. Drugs Drug Resist. 16 (2021) 140–147]

International journal for parasitology -- drugs and drug resistance, 2022-04, Vol.18, p.103-103

2022

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Schistosome Sulfotransferases: Mode of Action, Expression and Localization

Pharmaceutics, 2022-07, Vol.14 (7), p.1416

2022

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A modular PROTAC design for target destruction using a degradation signal based on a single amino acid

The Journal of biological chemistry, 2019-10, Vol.294 (41), p.15172-15175

2019

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Structure–Activity Relationship for Small Molecule Inhibitors of Nicotinamide N‑Methyltransferase

Journal of medicinal chemistry, 2017-06, Vol.60 (12), p.5015-5028

2017

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Targeting Candida albicans filamentation for antifungal drug development

Virulence, 2017-02, Vol.8 (2), p.150-158

2017

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Asymmetric Synthesis of CIDD-0072424 via an Enantioselective Nitro-Mannich Reaction: A Central Nervous System Penetrant, Selective Small Molecule Inhibitor of Protein Kinase C Epsilon

Journal of organic chemistry, 2024-04, Vol.89 (7), p.5134-5141

2024

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Structure–Activity Relationships of New Natural Product-Based Diaryloxazoles with Selective Activity against Androgen Receptor-Positive Breast Cancer Cells

Journal of medicinal chemistry, 2017-11, Vol.60 (22), p.9275-9289

2017

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Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N‑Methyltransferase Activity

Biochemistry (Easton), 2017-02, Vol.56 (6), p.824-832

2017

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Synthesis and SAR of novel capsazepine analogs with significant anti-cancer effects in multiple cancer types

Bioorganic & medicinal chemistry, 2019-01, Vol.27 (1), p.208-215

2019

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Modulation of α1β3γ2 GABAA receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helix

Proceedings of the National Academy of Sciences - PNAS, 2021-02, Vol.118 (8), p.1-8

2021

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Tamoxifen blocks retrograde trafficking of Shiga toxin 1 and 2 and protects against lethal toxicosis

Life science alliance, 2019-06, Vol.2 (3), p.e201900439

2019

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Molecular dynamics study of human carbonic anhydrase II in complex with Zn(2+) and acetazolamide on the basis of all-atom force field simulations

Biophysical chemistry, 2016-07, Vol.214-215, p.54-60

2016

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Molecular dynamics study of human carbonic anhydrase II in complex with Zn2+ and acetazolamide on the basis of all-atom force field simulations

Biophysical chemistry, 2016-07, Vol.214-215, p.54-60

2016

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Corrigendum to “Synthesis and SAR of novel capsazepine analogs with significant anti-cancer effects in multiple cancer types” [Bioorg. Med. Chem. 27 (1) (2019) 208–215]

Bioorganic & medicinal chemistry, 2019-06, Vol.27 (11), p.2280-2280

2019

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A novel small molecule inhibitor of Candida albicans biofilm formation, filamentation and virulence with low potential for the development of resistance

NPJ biofilms and microbiomes, 2015-08, Vol.1 (1), p.15012-15012, Article 15012

2015

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Molecular docking analysis of mitochondrial pyruvate carrier (MPC) 1 and 2 with pyruvate and inhibitors: Thiazolidinediones currently in clinical trials to delay mild cognitive impairment and Alzheimer’s disease

Alzheimer's & dementia, 2015-07, Vol.11 (7), p.P760-P761

2015

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Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents

ACS medicinal chemistry letters, 2018-10, Vol.9 (10), p.967-973

2018

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Total Synthesis of (+)-7-Deoxypancratistatin: A Radical Cyclization Approach

Journal of the American Chemical Society, 1995-07, Vol.117 (27), p.7289-7290

1995

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A Second-Generation Radical-Based Synthesis of (+)-7-Deoxypancratistatin

Journal of organic chemistry, 1998-12, Vol.63 (25), p.9164-9165

1998

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Design, synthesis, and characterization of novel, nonquaternary reactivators of GF-inhibited human acetylcholinesterase

Bioorganic & medicinal chemistry letters, 2014-04, Vol.24 (7), p.1711-1714

2014

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Reductive cleavage of NO bonds in hydroxylamines and hydroxamic acid derivatives using samarium diiodide

Tetrahedron, 1999-10, Vol.55 (40), p.11755-11772

1999

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Diastereoselective 6-exo Radical Cyclizations of Oxime Ethers: Total Synthesis of 7-Deoxypancratistatin

Journal of organic chemistry, 1999-06, Vol.64 (12), p.4465-4476

1999

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Inhibition of Ca 2+ entry by capsazepine analog CIDD-99 prevents oral squamous carcinoma cell proliferation

Frontiers in physiology, 2022, Vol.13, p.969000

2022

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Tamoxifen Derivatives Alter Retromer-Dependent Endosomal Tubulation and Sorting to Block Retrograde Trafficking of Shiga Toxins

Inhibition of Ca2+ entry by capsazepine analog CIDD-99 prevents oral squamous carcinoma cell proliferation

Corrigendum to “Rational approach to drug discovery for human schistosomiasis” [Int. J. Parasitol. Drugs Drug Resist. 16 (2021) 140–147]

Schistosome Sulfotransferases: Mode of Action, Expression and Localization

A modular PROTAC design for target destruction using a degradation signal based on a single amino acid

Structure–Activity Relationship for Small Molecule Inhibitors of Nicotinamide N‑Methyltransferase

Targeting Candida albicans filamentation for antifungal drug development

Asymmetric Synthesis of CIDD-0072424 via an Enantioselective Nitro-Mannich Reaction: A Central Nervous System Penetrant, Selective Small Molecule Inhibitor of Protein Kinase C Epsilon

Structure–Activity Relationships of New Natural Product-Based Diaryloxazoles with Selective Activity against Androgen Receptor-Positive Breast Cancer Cells

Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N‑Methyltransferase Activity

Synthesis and SAR of novel capsazepine analogs with significant anti-cancer effects in multiple cancer types

Modulation of α1β3γ2 GABAA receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helix

Tamoxifen blocks retrograde trafficking of Shiga toxin 1 and 2 and protects against lethal toxicosis

Molecular dynamics study of human carbonic anhydrase II in complex with Zn(2+) and acetazolamide on the basis of all-atom force field simulations

Molecular dynamics study of human carbonic anhydrase II in complex with Zn2+ and acetazolamide on the basis of all-atom force field simulations

Corrigendum to “Synthesis and SAR of novel capsazepine analogs with significant anti-cancer effects in multiple cancer types” [Bioorg. Med. Chem. 27 (1) (2019) 208–215]

A novel small molecule inhibitor of Candida albicans biofilm formation, filamentation and virulence with low potential for the development of resistance

Molecular docking analysis of mitochondrial pyruvate carrier (MPC) 1 and 2 with pyruvate and inhibitors: Thiazolidinediones currently in clinical trials to delay mild cognitive impairment and Alzheimer’s disease

Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents

Total Synthesis of (+)-7-Deoxypancratistatin: A Radical Cyclization Approach

A Second-Generation Radical-Based Synthesis of (+)-7-Deoxypancratistatin

Design, synthesis, and characterization of novel, nonquaternary reactivators of GF-inhibited human acetylcholinesterase

Reductive cleavage of NO bonds in hydroxylamines and hydroxamic acid derivatives using samarium diiodide

Diastereoselective 6-exo Radical Cyclizations of Oxime Ethers: Total Synthesis of 7-Deoxypancratistatin

Inhibition of Ca 2+ entry by capsazepine analog CIDD-99 prevents oral squamous carcinoma cell proliferation

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