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The impact of human hyperekplexia mutations on glycine receptor structure and function

Molecular brain, 2014-01, Vol.7 (1), p.2-2

2014

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Mechanism of action of the insecticides, lindane and fipronil, on glycine receptor chloride channels

British journal of pharmacology, 2012-04, Vol.165 (8), p.2707-2720

2012

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Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors

Neurobiology of disease, 2020-07, Vol.140, p.104850-104850, Article 104850

2020

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Correlating Structural and Energetic Changes in Glycine Receptor Activation

The Journal of biological chemistry, 2015-02, Vol.290 (9), p.5621-5634

2015

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Inhibitory synapse deficits caused by familial α1 GABAA receptor mutations in epilepsy

Neurobiology of disease, 2017-12, Vol.108, p.213-224

2017

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GluClR-mediated inhibitory postsynaptic currents reveal targets for ivermectin and potential mechanisms of ivermectin resistance

PLoS pathogens, 2019-01, Vol.15 (1), p.e1007570-e1007570

2019

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Stoichiometry and Subunit Arrangement of α1β Glycine Receptors As Determined by Atomic Force Microscopy

Biochemistry (Easton), 2012-07, Vol.51 (26), p.5229-5231

2012

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Functional characterization of ivermectin binding sites in α1β2γ2L GABA(A) receptors

Frontiers in molecular neuroscience, 2015-09, Vol.8, p.55-55

2015

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Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABAA receptors

Cell & bioscience, 2022-04, Vol.12 (1), p.1-48, Article 48

2022

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Probing the Structural Mechanism of Partial Agonism in Glycine Receptors Using the Fluorescent Artificial Amino Acid, ANAP

ACS chemical biology, 2017-03, Vol.12 (3), p.805-813

2017

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Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin

Frontiers in molecular neuroscience, 2012-01, Vol.5, p.60

2012

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Effects of GABAA Receptor α3 Subunit Epilepsy Mutations on Inhibitory Synaptic Signaling

Frontiers in molecular neuroscience, 2020-11, Vol.13, p.602559-602559

2020

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Loss, Gain and Altered Function of GlyR α2 Subunit Mutations in Neurodevelopmental Disorders

Frontiers in molecular neuroscience, 2022-04, Vol.15, p.886729-886729

2022

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Fluorescence-based high-throughput functional profiling of ligand-gated ion channels at the level of single cells

PloS one, 2013-03, Vol.8 (3), p.e58479-e58479

2013

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SAHA (Vorinostat) Corrects Inhibitory Synaptic Deficits Caused by Missense Epilepsy Mutations to the GABAA Receptor γ2 Subunit

Frontiers in molecular neuroscience, 2018-03, Vol.11, p.89-89

2018

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Structure-Function Analysis of the GlyR α2 Subunit Autism Mutation p.R323L Reveals a Gain-of-Function

Frontiers in molecular neuroscience, 2017-05, Vol.10, p.158

2017

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Novel missense mutations in the glycine receptor β subunit gene ( GLRB ) in startle disease

Neurobiology of disease, 2013-04, Vol.52, p.137-149

2013

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GLRB is the third major gene of effect in hyperekplexia

Human molecular genetics, 2013-03, Vol.22 (5), p.927-940

2013

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Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine

Biochemical pharmacology, 2008-10, Vol.76 (8), p.1014-1023

2008

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Physiological and pharmacological properties of inhibitory postsynaptic currents mediated by α5β1γ2, α5β2γ2 and α5β3γ2 GABAA receptors

Neuropharmacology, 2017-10, Vol.125, p.243-253

2017

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Generation of Functional Inhibitory Synapses Incorporating Defined Combinations of GABA(A) or Glycine Receptor Subunits

Frontiers in molecular neuroscience, 2015-12, Vol.8, p.80-80

2015

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Structure/Function Studies of the α4 Subunit Reveal Evolutionary Loss of a GlyR Subtype Involved in Startle and Escape Responses

Frontiers in molecular neuroscience, 2018-01, Vol.11, p.23

2018

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γ1-Containing GABA-A Receptors Cluster at Synapses Where they Mediate Slower Synaptic Currents than γ2-Containing GABA-A Receptors

Frontiers in molecular neuroscience, 2017-06, Vol.10, p.178-178

2017

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proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore

Journal of neurochemistry, 2007-10, Vol.103 (2), p.580-589

2007

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Phosphorylation mediated structural and functional changes in pentameric ligand-gated ion channels: Implications for drug discovery

The international journal of biochemistry & cell biology, 2014-08, Vol.53, p.218-223

2014

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The impact of human hyperekplexia mutations on glycine receptor structure and function

Mechanism of action of the insecticides, lindane and fipronil, on glycine receptor chloride channels

Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors

Correlating Structural and Energetic Changes in Glycine Receptor Activation

Inhibitory synapse deficits caused by familial α1 GABAA receptor mutations in epilepsy

GluClR-mediated inhibitory postsynaptic currents reveal targets for ivermectin and potential mechanisms of ivermectin resistance

Stoichiometry and Subunit Arrangement of α1β Glycine Receptors As Determined by Atomic Force Microscopy

Functional characterization of ivermectin binding sites in α1β2γ2L GABA(A) receptors

Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABAA receptors

Probing the Structural Mechanism of Partial Agonism in Glycine Receptors Using the Fluorescent Artificial Amino Acid, ANAP

Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin

Effects of GABAA Receptor α3 Subunit Epilepsy Mutations on Inhibitory Synaptic Signaling

Loss, Gain and Altered Function of GlyR α2 Subunit Mutations in Neurodevelopmental Disorders

Fluorescence-based high-throughput functional profiling of ligand-gated ion channels at the level of single cells

SAHA (Vorinostat) Corrects Inhibitory Synaptic Deficits Caused by Missense Epilepsy Mutations to the GABAA Receptor γ2 Subunit

Structure-Function Analysis of the GlyR α2 Subunit Autism Mutation p.R323L Reveals a Gain-of-Function

Novel missense mutations in the glycine receptor β subunit gene ( GLRB ) in startle disease

GLRB is the third major gene of effect in hyperekplexia

Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine

Physiological and pharmacological properties of inhibitory postsynaptic currents mediated by α5β1γ2, α5β2γ2 and α5β3γ2 GABAA receptors

Generation of Functional Inhibitory Synapses Incorporating Defined Combinations of GABA(A) or Glycine Receptor Subunits

Structure/Function Studies of the α4 Subunit Reveal Evolutionary Loss of a GlyR Subtype Involved in Startle and Escape Responses

γ1-Containing GABA-A Receptors Cluster at Synapses Where they Mediate Slower Synaptic Currents than γ2-Containing GABA-A Receptors

proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore

Phosphorylation mediated structural and functional changes in pentameric ligand-gated ion channels: Implications for drug discovery

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