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Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity

Journal of medicinal chemistry, 2017-07, Vol.60 (14), p.5990-6017

2017

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Pharmacokinetics and metabolism of [14C]eplerenone after oral administration to humans

Drug metabolism and disposition, 2003-11, Vol.31 (11), p.1448

2003

Volltextzugriff (PDF)

Dynamic modeling of cytochrome P450 inhibition in vitro: impact of inhibitor depletion on IC₅₀ shift

Drug metabolism and disposition, 2013-07, Vol.41 (7), p.1433

2013

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Applications of parallel synthetic lead hopping and pharmacophore-based virtual screening in the discovery of efficient glycine receptor potentiators

European journal of medicinal chemistry, 2017-09, Vol.137, p.63-75

2017

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Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective Na V 1.7 Inhibitors

Journal of medicinal chemistry, 2016-09, Vol.59 (17), p.7818-7839

2016

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An examination of IC50 and IC50-shift experiments in assessing time-dependent inhibition of CYP3A4, CYP2D6 and CYP2C9 in human liver microsomes

Drug metabolism letters, 2008-01, Vol.2 (1), p.51

2008

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Long-acting [kappa] opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity

BMC pharmacology, 2012-01, Vol.12 (1)

2012

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Leaders in Sales and Sales Management

The Journal of personal selling & sales management, 1981-01, Vol.1 (1), p.90-91

1981

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Comparison of Methods of Initial Ascertainment in 58 Cases of Propionic Acidemia Enrolled in the Inborn Errors of Metabolism Information System Reveals Significant Differences in Time to Evaluation and Symptoms at Presentation

The Journal of pediatrics, 2017-01, Vol.180, p.200-205.e8

2017

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Outcomes and genotype-phenotype correlations in 52 individuals with VLCAD deficiency diagnosed by NBS and enrolled in the IBEM-IS database

Molecular genetics and metabolism, 2016-08, Vol.118 (4), p.272-281

2016

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Measuring Pediatric Hospital Readmission Rates to Drive Quality Improvement

Academic pediatrics, 2014-09, Vol.14 (5), p.S39-S46

2014

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Delays in melanoma presentation during the COVID-19 pandemic: A nationwide multi-institutional cohort study

Journal of the American Academy of Dermatology, 2022-11, Vol.87 (5), p.1217-1219

2022

Volltextzugriff (PDF)

Anti-streptococcal, tubulin, and dopamine receptor 2 antibodies in children with PANDAS and Tourette syndrome: Single-point and longitudinal assessments

Journal of neuroimmunology, 2013-11, Vol.264 (1), p.106-113

2013

Volltextzugriff (PDF)

Decomposition of monazite concentrate in sulphuric acid

Canadian metallurgical quarterly, 2018-10, Vol.57 (4), p.422-433

2018

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Major features and forcing of high-latitude northern hemisphere atmospheric circulation using a 110,000-year-long glaciochemical series

Journal of Geophysical Research, Washington, DC, 1997-11, Vol.102 (C12), p.26345-26366

1997

Volltextzugriff (PDF)

Characterization of the neutron detector upgrade to the GP-SANS and Bio-SANS instruments at HFIR

Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment, 2012-11, Vol.693, p.179-185

2012

Volltextzugriff (PDF)

Use of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical Species

Drug metabolism and disposition, 2019-10, Vol.47 (10), p.1111-1121

2019

Volltextzugriff (PDF)

Detection and photothermal actuation of microcantilever oscillations in air and liquid using a modified DVD optical pickup

Sensors and actuators. A. Physical., 2016-09, Vol.248, p.6-9

2016

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Cosmetic Breast Surgery

1, 2020

Volltextzugriff (PDF)

Response of Soybean Cultivars to Bean pod mottle virus Infection

Plant disease, 2007-06, Vol.91 (6), p.719-726

2007

Volltextzugriff (PDF)

Efficacy of different fixation devices in maintaining an initial reduction for surgically managed distal radius fractures

Canadian Journal of Surgery, 2009-10, Vol.52 (5), p.E161-E166

2009

Volltextzugriff (PDF)

Cosmetic Breast Surgery

Volltextzugriff (PDF)

Science and the Soviet order

Soviet studies, 1992, Vol.44 (3), p.536-536

1992

Volltextzugriff (PDF)

Creating Earthquakes to Change Organizational Mindsets [and Executive Commentary]

The Academy of Management executive (1993), 1994-11, Vol.8 (4), p.31-46

1994

Volltextzugriff (PDF)

SIGPLAN(Tutorial Session)

Proceedings of the 1976 annual conference, 1976, p.387-389

Berry, Daniel M.

1976

Volltextzugriff (PDF)

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Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity

Pharmacokinetics and metabolism of [14C]eplerenone after oral administration to humans

Dynamic modeling of cytochrome P450 inhibition in vitro: impact of inhibitor depletion on IC₅₀ shift

Applications of parallel synthetic lead hopping and pharmacophore-based virtual screening in the discovery of efficient glycine receptor potentiators

Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective Na V 1.7 Inhibitors

An examination of IC50 and IC50-shift experiments in assessing time-dependent inhibition of CYP3A4, CYP2D6 and CYP2C9 in human liver microsomes

Long-acting [kappa] opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity

Leaders in Sales and Sales Management

Comparison of Methods of Initial Ascertainment in 58 Cases of Propionic Acidemia Enrolled in the Inborn Errors of Metabolism Information System Reveals Significant Differences in Time to Evaluation and Symptoms at Presentation

Outcomes and genotype-phenotype correlations in 52 individuals with VLCAD deficiency diagnosed by NBS and enrolled in the IBEM-IS database

Measuring Pediatric Hospital Readmission Rates to Drive Quality Improvement

Delays in melanoma presentation during the COVID-19 pandemic: A nationwide multi-institutional cohort study

Anti-streptococcal, tubulin, and dopamine receptor 2 antibodies in children with PANDAS and Tourette syndrome: Single-point and longitudinal assessments

Decomposition of monazite concentrate in sulphuric acid

Major features and forcing of high-latitude northern hemisphere atmospheric circulation using a 110,000-year-long glaciochemical series

Characterization of the neutron detector upgrade to the GP-SANS and Bio-SANS instruments at HFIR

Use of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical Species

Detection and photothermal actuation of microcantilever oscillations in air and liquid using a modified DVD optical pickup

Cosmetic Breast Surgery

Response of Soybean Cultivars to Bean pod mottle virus Infection

Efficacy of different fixation devices in maintaining an initial reduction for surgically managed distal radius fractures

Cosmetic Breast Surgery

Science and the Soviet order

Creating Earthquakes to Change Organizational Mindsets [and Executive Commentary]

SIGPLAN(Tutorial Session)

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