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Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan

Cancer research (Chicago, Ill.), 2005-08, Vol.65 (15), p.6850-6857

2005

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Mechanism-based inactivation of CYP2B1 and its F-helix mutant by two tert-butyl acetylenic compounds: covalent modification of prosthetic heme versus apoprotein

The Journal of pharmacology and experimental therapeutics, 2009-11, Vol.331 (2), p.392-403

2009

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Modification of Serine 360 by a Reactive Intermediate of 17-α-Ethynylestradiol Results in Mechanism-Based Inactivation of Cytochrome P450s 2B1 and 2B6

Chemical research in toxicology, 2008-10, Vol.21 (10), p.1956-1963

2008

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Hypersensitive Radical Probes and the Mechanisms of Cytochrome P450-Catalyzed Hydroxylation Reactions

Accounts of chemical research, 2000-07, Vol.33 (7), p.449-455

2000

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In vitro activation of 7-benzyloxyresorufin O-debenzylation and nifedipine oxidation in human liver microsomes

Xenobiotica, 2003-07, Vol.33 (7), p.717-729

2003

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Amino Acid Residues Critical for Differential Inhibition of CYP2B4, CYP2B5, and CYP2B1 by Phenylimidazoles

Molecular pharmacology, 2001-03, Vol.59 (3), p.475-484

2001

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Effect of Conformational Dynamics on Substrate Recognition and Specificity as Probed by the Introduction of a de Novo Disulfide Bond into Cytochrome P450 2B1

The Journal of biological chemistry, 2009-09, Vol.284 (38), p.25678-25686

2009

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Covalent modification of Thr302 in cytochrome P450 2B1 by the mechanism-based inactivator 4-tert-butylphenylacetylene

The Journal of pharmacology and experimental therapeutics, 2010-06, Vol.333 (3), p.663-669

2010

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Prodrug bioactivation and oncolysis of diffuse liver metastases by a herpes simplex virus 1 mutant that expresses the CYP2B1 transgene

Cancer, 2002-09, Vol.95 (5), p.1171-1181

2002

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Enhancing crop yields through improvements in the efficiency of photosynthesis and respiration

The New phytologist, 2023-01, Vol.237 (1), p.60-77

2023

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Metabolism of N,N',N"-triethylenethiophosphoramide by CYP2B1 and CYP2B6 results in the inactivation of both isoforms by two distinct mechanisms

The Journal of pharmacology and experimental therapeutics, 2004-09, Vol.310 (3), p.1011-1019

2004

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Biological effects of Byrsocarpus coccineus in vitro

Pharmaceutical biology, 2011-02, Vol.49 (2), p.152-160

2011

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Exploring QSARs for Binding Affinity of Azoles with CYP2B and CYP3A Enzymes Using GFA and G/PLS Techniques

Chemical biology & drug design, 2008-05, Vol.71 (5), p.464-473

2008

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Association of Blood Pressure Lowering Intensity With White Matter Network Integrity in Patients With Cerebral Small Vessel Disease

Neurology, 2022-10, Vol.99 (17), p.e1945

2022

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Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP)

DNA and cell biology, 2004-02, Vol.23 (2), p.81-91

2004

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Aetiology, risk factors and microbiota composition in children with prolonged diarrhoea: A prospective case–controlled cohort study

Acta Paediatrica, 2024-03, Vol.113 (3), p.598-605

2024

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Effects of body size and countermeasure exercise on estimates of life support resources during all-female crewed exploration missions

Scientific reports, 2023-04, Vol.13 (1), p.5950-12, Article 5950

2023

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Reduced graphene oxide-persimmon tannin/Pt@Pd nanozyme–based cascade colorimetric sensor for detection of 1,5-anhydroglucitol

Analytical and bioanalytical chemistry, 2023-12, Vol.415 (29-30), p.7103-7115

2023

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Structure–Function Analysis of Human Cytochrome P450 3A4 Using 7-Alkoxycoumarins as Active-Site Probes

Archives of biochemistry and biophysics, 2000-01, Vol.373 (2), p.335-345

2000

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Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-arterially in patients with advanced-stage pancreatic carcinoma : a phase I/II study

Journal of molecular medicine (Berlin, Germany), 1999-04, Vol.77 (4), p.393-398

1999

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Novel clinical strategies for the treatment of pancreatic carcinoma

Trends in Molecular Medicine, 2001, Vol.7 (1), p.30-37

2001

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Interaction of C1q with IgG1, C-reactive Protein and Pentraxin 3: Mutational Studies Using Recombinant Globular Head Modules of Human C1q A, B, and C Chains

Biochemistry (Easton), 2006-04, Vol.45 (13), p.4093-4104

2006

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Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds

Xenobiotica, 1999, Vol.29 (12), p.1191-1202

1999

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Stoichiometry of 7-ethoxycoumarin metabolism by cytochrome P450 2B1 wild-type and five active-site mutants

FEBS letters, 1997-10, Vol.416 (1), p.77-80

1997

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Microencapsulated cell-mediated treatment of inoperable pancreatic carcinoma

The Lancet (British edition), 2001-05, Vol.357 (9268), p.1591-1592

2001

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Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan

Mechanism-based inactivation of CYP2B1 and its F-helix mutant by two tert-butyl acetylenic compounds: covalent modification of prosthetic heme versus apoprotein

Modification of Serine 360 by a Reactive Intermediate of 17-α-Ethynylestradiol Results in Mechanism-Based Inactivation of Cytochrome P450s 2B1 and 2B6

Hypersensitive Radical Probes and the Mechanisms of Cytochrome P450-Catalyzed Hydroxylation Reactions

In vitro activation of 7-benzyloxyresorufin O-debenzylation and nifedipine oxidation in human liver microsomes

Amino Acid Residues Critical for Differential Inhibition of CYP2B4, CYP2B5, and CYP2B1 by Phenylimidazoles

Effect of Conformational Dynamics on Substrate Recognition and Specificity as Probed by the Introduction of a de Novo Disulfide Bond into Cytochrome P450 2B1

Covalent modification of Thr302 in cytochrome P450 2B1 by the mechanism-based inactivator 4-tert-butylphenylacetylene

Prodrug bioactivation and oncolysis of diffuse liver metastases by a herpes simplex virus 1 mutant that expresses the CYP2B1 transgene

Enhancing crop yields through improvements in the efficiency of photosynthesis and respiration

Metabolism of N,N',N"-triethylenethiophosphoramide by CYP2B1 and CYP2B6 results in the inactivation of both isoforms by two distinct mechanisms

Biological effects of Byrsocarpus coccineus in vitro

Exploring QSARs for Binding Affinity of Azoles with CYP2B and CYP3A Enzymes Using GFA and G/PLS Techniques

Association of Blood Pressure Lowering Intensity With White Matter Network Integrity in Patients With Cerebral Small Vessel Disease

Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP)

Aetiology, risk factors and microbiota composition in children with prolonged diarrhoea: A prospective case–controlled cohort study

Effects of body size and countermeasure exercise on estimates of life support resources during all-female crewed exploration missions

Reduced graphene oxide-persimmon tannin/Pt@Pd nanozyme–based cascade colorimetric sensor for detection of 1,5-anhydroglucitol

Structure–Function Analysis of Human Cytochrome P450 3A4 Using 7-Alkoxycoumarins as Active-Site Probes

Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-arterially in patients with advanced-stage pancreatic carcinoma : a phase I/II study

Novel clinical strategies for the treatment of pancreatic carcinoma

Interaction of C1q with IgG1, C-reactive Protein and Pentraxin 3: Mutational Studies Using Recombinant Globular Head Modules of Human C1q A, B, and C Chains

Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds

Stoichiometry of 7-ethoxycoumarin metabolism by cytochrome P450 2B1 wild-type and five active-site mutants

Microencapsulated cell-mediated treatment of inoperable pancreatic carcinoma

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