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Engineering amyloid-like assemblies from unstructured peptides via site-specific lipid conjugation

PloS one, 2014-09, Vol.9 (9), p.e105641

2014

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Synthesis of Components for the Generation of Constitutional Dynamic Analogues of Nucleic Acids

Helvetica chimica acta, 2008-01, Vol.91 (1), p.1-20

2008

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Dynamic Nuclear Polarization NMR Spectroscopy: Revealing Multiple Conformations in Lipid-Anchored Peptide Vaccines

Angewandte Chemie (International ed.), 2013-10, Vol.52 (41), p.10905-10908

International ed. in English, 2013

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DyNAs: Constitutional Dynamic Nucleic Acid Analogues

Chemistry : a European journal, 2006-11, Vol.12 (33), p.8581-8588

2006

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A liposomal anti-phospho-tau vaccine demonstrates higher immunogenicity and specificity than a classical peptide vaccine approach

Alzheimer's & dementia, 2013-07, Vol.9 (4), p.P326-P326

2013

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Phospho-tau–specific vaccine for the treatment of tau pathology

Alzheimer's & dementia, 2012-07, Vol.8 (4), p.P398-P399

2012

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Novel phospho-Tau specific monoclonal antibodies for the treatment of Tau-mediated pathology

Alzheimer's & dementia, 2011-07, Vol.7 (4), p.S480-S480

2011

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The safety profile of ACI-24, an oligo-specific amyloid beta vaccine, demonstrated decrease of large microbleedings in brain of aged Alzheimer's disease mouse model

Alzheimer's & dementia, 2009-07, Vol.5 (4), p.P425-P426

2009

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Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM)

Chemical communications (Cambridge, England), 2004-03 (5), p.516-517

2004

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Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM)

Organic & biomolecular chemistry, 2003-10, Vol.1 (19), p.3277-3292

2003

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Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM)This paper is dedicated to Professor Heinz G. Floss on the occasion of his 70th birthday.Electronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/cc/b3/b315768g

Chemical communications (Cambridge, England), 2004-02 (5), p.516

2004

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Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM)Electronic supplementary information (ESI) available: experimental details (16 Figures, 3 Tables). See http://www.rsc.org/suppdata/ob/b3/b306156f

Organic & biomolecular chemistry, 2003-09, Vol.1 (19), p.3277

2003

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Discovery and preclinical characterization of 18FPI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies

European journal of nuclear medicine and molecular imaging, 2019-09, Vol.46 (10), p.2178

2019

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Synthesis and nucleic-acid-binding properties of sulfamide- and 3 '-N-sulfamate-modified DNA

Perkin 1 : an international journal of organic and bio-organic chemistry, 2002-02 (4), p.485-495

2002

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A general route for the synthesis of triazacyclononane functionalised with one, two or three pendant phosphine arms: crystal structure of [Zn2L2Cl3][ClO4], L =N-(diphenylphosphinopropyl)-1,4,7-triazacyclononane

Chemical communications (Cambridge, England), 1996 (15), p.1817

1996

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NMR-Spektroskopie in Kombination mit dynamischer Kernpolarisation enthüllt mehrere Konformationen in Lipid-verankerten Peptid-Impfstoffen

Angewandte Chemie, 2013-10, Vol.125 (41), p.11106-11109

2013

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Synthesis and nucleic-acid-binding properties of sulfamide- and 3′-N-sulfamate-modified DNAElectronic supplementary information (ESI) available: typical melting curves obtained from thermal denaturation of modified oligonucleotides with complementary DNA and RNA. See http://www.rsc.org/suppdata/p1/b1/b110603c

Perkin 1 : an international journal of organic and bio-organic chemistry, 2002-02 (4), p.485-495

2002

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O2–06–04: A liposomal anti‐phospho‐tau vaccine demonstrates higher immunogenicity and specificity than a classical peptide vaccine approach

Alzheimer's & dementia, 2013-07, Vol.9 (4S_Part_8), p.P326-P326

2013

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P2‐525: Novel phospho‐Tau specific monoclonal antibodies for the treatment of Tau‐mediated pathology

Alzheimer's & dementia, 2011-07, Vol.7 (4S_Part_14), p.S480-S480

2011

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P2‐387: Phospho‐tau–specific vaccine for the treatment of tau pathology

Alzheimer's & dementia, 2012-07, Vol.8 (4S_Part_11), p.P398-P399

2012

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P3‐281: The safety profile of ACI‐24, an oligo‐specific amyloid beta vaccine, demonstrated decrease of large microbleedings in brain of aged Alzheimer's disease mouse model

Alzheimer's & dementia, 2009-07, Vol.5 (4S_Part_14), p.P425-P426

2009

Volltextzugriff (PDF)

Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy. e72301

PloS one, 2013-08, Vol.8 (8)

2013

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Unusual RNA and DNA binding properties of a novel pyrrolidine–amide oligonucleotide mimic (POM)

Chemical communications (Cambridge, England), 2000-01 (22), p.2251-2252

2000

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Replacement of the phosphodiester linkage in DNA with sulfamide and 3′-N-sulfamate groups

Chemical communications (Cambridge, England), 2000-01 (9), p.765-766

2000

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NMR‐Spektroskopie in Kombination mit dynamischer Kernpolarisation enthüllt mehrere Konformationen in Lipid‐verankerten Peptid‐Impfstoffen

Angewandte Chemie, 2013-10, Vol.125 (41), p.11106-11109

2013

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1 – 25 von 758

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Engineering amyloid-like assemblies from unstructured peptides via site-specific lipid conjugation

Synthesis of Components for the Generation of Constitutional Dynamic Analogues of Nucleic Acids

Dynamic Nuclear Polarization NMR Spectroscopy: Revealing Multiple Conformations in Lipid-Anchored Peptide Vaccines

DyNAs: Constitutional Dynamic Nucleic Acid Analogues

A liposomal anti-phospho-tau vaccine demonstrates higher immunogenicity and specificity than a classical peptide vaccine approach

Phospho-tau–specific vaccine for the treatment of tau pathology

Novel phospho-Tau specific monoclonal antibodies for the treatment of Tau-mediated pathology

The safety profile of ACI-24, an oligo-specific amyloid beta vaccine, demonstrated decrease of large microbleedings in brain of aged Alzheimer's disease mouse model

Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM)

Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM)

Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM)Electronic supplementary information (ESI) available: experimental details (16 Figures, 3 Tables). See http://www.rsc.org/suppdata/ob/b3/b306156f

Discovery and preclinical characterization of 18FPI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies

Synthesis and nucleic-acid-binding properties of sulfamide- and 3 '-N-sulfamate-modified DNA

A general route for the synthesis of triazacyclononane functionalised with one, two or three pendant phosphine arms: crystal structure of [Zn2L2Cl3][ClO4], L =N-(diphenylphosphinopropyl)-1,4,7-triazacyclononane

NMR-Spektroskopie in Kombination mit dynamischer Kernpolarisation enthüllt mehrere Konformationen in Lipid-verankerten Peptid-Impfstoffen

O2–06–04: A liposomal anti‐phospho‐tau vaccine demonstrates higher immunogenicity and specificity than a classical peptide vaccine approach

P2‐525: Novel phospho‐Tau specific monoclonal antibodies for the treatment of Tau‐mediated pathology

P2‐387: Phospho‐tau–specific vaccine for the treatment of tau pathology

P3‐281: The safety profile of ACI‐24, an oligo‐specific amyloid beta vaccine, demonstrated decrease of large microbleedings in brain of aged Alzheimer's disease mouse model

Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy. e72301

Unusual RNA and DNA binding properties of a novel pyrrolidine–amide oligonucleotide mimic (POM)

Replacement of the phosphodiester linkage in DNA with sulfamide and 3′-N-sulfamate groups

NMR‐Spektroskopie in Kombination mit dynamischer Kernpolarisation enthüllt mehrere Konformationen in Lipid‐verankerten Peptid‐Impfstoffen

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