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Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan

Cancer research (Chicago, Ill.), 2005-08, Vol.65 (15), p.6850-6857

2005

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Functional role of residues in the helix B′ region of cytochrome P450 2B1

Archives of biochemistry and biophysics, 2005-03, Vol.435 (1), p.157-165

2005

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Hypersensitive Radical Probes and the Mechanisms of Cytochrome P450-Catalyzed Hydroxylation Reactions

Accounts of chemical research, 2000-07, Vol.33 (7), p.449-455

2000

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Mutagenesis and molecular dynamics suggest structural and functional roles for residues in the N-terminal portion of the cytochrome P450 2B1 I helix

Archives of biochemistry and biophysics, 2004-03, Vol.423 (2), p.266-276

2004

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Pressure prods an elusive superconductor to emerge at last

Nature (London), 2022-05, Vol.605 (7908), p.10-10

2022

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Effect of Conformational Dynamics on Substrate Recognition and Specificity as Probed by the Introduction of a de Novo Disulfide Bond into Cytochrome P450 2B1

The Journal of biological chemistry, 2009-09, Vol.284 (38), p.25678-25686

2009

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Investigation of the Mechanisms Underlying the Differential Effects of the K262R Mutation of P450 2B6 on Catalytic Activity

Molecular pharmacology, 2008-10, Vol.74 (4), p.990-999

2008

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Prodrug bioactivation and oncolysis of diffuse liver metastases by a herpes simplex virus 1 mutant that expresses the CYP2B1 transgene

Cancer, 2002-09, Vol.95 (5), p.1171-1181

2002

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Lateral segregation of anionic phospholipids in model membranes induced by cytochrome P450 2B1: Bi-directional coupling between CYP2B1 and anionic phospholipid

Archives of biochemistry and biophysics, 2007-12, Vol.468 (2), p.226-233

2007

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The prod eff: Partially producing items moderates the production effect

Psychonomic bulletin & review, 2024-02, Vol.31 (1), p.373-379

2024

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Mutation of Tyrosine 190 to Alanine Eliminates the Inactivation of Cytochrome P450 2B1 by Peroxynitrite

Chemical research in toxicology, 2003-02, Vol.16 (2), p.129-136

2003

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Enhancing crop yields through improvements in the efficiency of photosynthesis and respiration

The New phytologist, 2023-01, Vol.237 (1), p.60-77

2023

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Substrate Routes to the Buried Active Site May Vary among Cytochromes P450: Mutagenesis of the F−G Region in P450 2B1

Chemical research in toxicology, 2002-11, Vol.15 (11), p.1407-1413

2002

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The Highly Conserved Glu149 and Tyr190 Residues Contribute To Peroxynitrite-Mediated Nitrotyrosine Formation and the Catalytic Activity of Cytochrome P450 2B1

Chemical research in toxicology, 2005-08, Vol.18 (8), p.1203-1210

2005

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Association of Blood Pressure Lowering Intensity With White Matter Network Integrity in Patients With Cerebral Small Vessel Disease

Neurology, 2022-10, Vol.99 (17), p.e1945

2022

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Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP)

DNA and cell biology, 2004-02, Vol.23 (2), p.81

2004

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2,2‘,3,3‘,6,6‘-Hexachlorobiphenyl Hydroxylation by Active Site Mutants of Cytochrome P450 2B1 and 2B11

Chemical research in toxicology, 1999-08, Vol.12 (8), p.690-699

1999

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Effects of body size and countermeasure exercise on estimates of life support resources during all-female crewed exploration missions

Scientific reports, 2023-04, Vol.13 (1), p.5950-5950, Article 5950

2023

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Roles of the threonine 407, aspartic acid 417, and threonine 419 residues in P450 2B1 in metabolism

Biochemical and biophysical research communications, 2005-12, Vol.338 (1), p.386-393

2005

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P(450)/NADPH/O(2)- and P(450)/PhIO-catalyzed N-dealkylations are mechanistically distinct

Journal of the American Chemical Society, 2005-02, Vol.127 (5), p.1376-1377

2005

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Is an Acute Perioperative Increase in Creatinine Production Rate a Potential Mechanism for an Early Creatinine-Based Signal of Renal Injury After Cardiac Surgery?

Journal of cardiothoracic and vascular anesthesia, 2022-08, Vol.36 (8), p.3114-3123

2022

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Effects of Heat Acclimation Following Heat Acclimatization on Whole Body Heat Exchange in Trained Endurance Athletes

International journal of environmental research and public health, 2022-05, Vol.19 (11), p.6412

2022

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Structure–Function Analysis of Human Cytochrome P450 3A4 Using 7-Alkoxycoumarins as Active-Site Probes

Archives of biochemistry and biophysics, 2000-01, Vol.373 (2), p.335-345

2000

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Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-arterially in patients with advanced-stage pancreatic carcinoma : a phase I/II study

Journal of molecular medicine (Berlin, Germany), 1999-04, Vol.77 (4), p.393-398

1999

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Novel clinical strategies for the treatment of pancreatic carcinoma

Trends in Molecular Medicine, 2001, Vol.7 (1), p.30-37

2001

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Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan

Functional role of residues in the helix B′ region of cytochrome P450 2B1

Hypersensitive Radical Probes and the Mechanisms of Cytochrome P450-Catalyzed Hydroxylation Reactions

Mutagenesis and molecular dynamics suggest structural and functional roles for residues in the N-terminal portion of the cytochrome P450 2B1 I helix

Pressure prods an elusive superconductor to emerge at last

Effect of Conformational Dynamics on Substrate Recognition and Specificity as Probed by the Introduction of a de Novo Disulfide Bond into Cytochrome P450 2B1

Investigation of the Mechanisms Underlying the Differential Effects of the K262R Mutation of P450 2B6 on Catalytic Activity

Prodrug bioactivation and oncolysis of diffuse liver metastases by a herpes simplex virus 1 mutant that expresses the CYP2B1 transgene

Lateral segregation of anionic phospholipids in model membranes induced by cytochrome P450 2B1: Bi-directional coupling between CYP2B1 and anionic phospholipid

The prod eff: Partially producing items moderates the production effect

Mutation of Tyrosine 190 to Alanine Eliminates the Inactivation of Cytochrome P450 2B1 by Peroxynitrite

Enhancing crop yields through improvements in the efficiency of photosynthesis and respiration

Substrate Routes to the Buried Active Site May Vary among Cytochromes P450: Mutagenesis of the F−G Region in P450 2B1

The Highly Conserved Glu149 and Tyr190 Residues Contribute To Peroxynitrite-Mediated Nitrotyrosine Formation and the Catalytic Activity of Cytochrome P450 2B1

Association of Blood Pressure Lowering Intensity With White Matter Network Integrity in Patients With Cerebral Small Vessel Disease

Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP)

2,2‘,3,3‘,6,6‘-Hexachlorobiphenyl Hydroxylation by Active Site Mutants of Cytochrome P450 2B1 and 2B11

Effects of body size and countermeasure exercise on estimates of life support resources during all-female crewed exploration missions

Roles of the threonine 407, aspartic acid 417, and threonine 419 residues in P450 2B1 in metabolism

P(450)/NADPH/O(2)- and P(450)/PhIO-catalyzed N-dealkylations are mechanistically distinct

Is an Acute Perioperative Increase in Creatinine Production Rate a Potential Mechanism for an Early Creatinine-Based Signal of Renal Injury After Cardiac Surgery?

Effects of Heat Acclimation Following Heat Acclimatization on Whole Body Heat Exchange in Trained Endurance Athletes

Structure–Function Analysis of Human Cytochrome P450 3A4 Using 7-Alkoxycoumarins as Active-Site Probes

Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-arterially in patients with advanced-stage pancreatic carcinoma : a phase I/II study

Novel clinical strategies for the treatment of pancreatic carcinoma

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