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Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3

Cell reports (Cambridge), 2014-04, Vol.7 (1), p.86-93

2014

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A Functional Genetic Screen Identifies the Phosphoinositide 3-kinase Pathway as a Determinant of Resistance to Fibroblast Growth Factor Receptor Inhibitors in FGFR Mutant Urothelial Cell Carcinoma

European urology, 2017-06, Vol.71 (6), p.858-862

2017

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High-Throughput Cell-Based Screening of 4910 Known Drugs and Drug-like Small Molecules Identifies Disulfiram as an Inhibitor of Prostate Cancer Cell Growth

Clinical cancer research, 2009-10, Vol.15 (19), p.6070-6078

2009

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Identification of signalling cascades involved in red blood cell shrinkage and vesiculation

Bioscience reports, 2015-04, Vol.35 (2), p.e00187

2015

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Language policies in Finland and Sweden: interdisciplinary and multi-sited comparisons

1st ed., 2014

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Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint

Carcinogenesis (New York), 2009-06, Vol.30 (6), p.1032-1040

2009

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Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase

BMC cancer, 2010-01, Vol.10 (1), p.7-7, Article 7

2010

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Quaternary Structure and Metal Ion Requirement of Family II Pyrophosphatases from Bacillus subtilis,Streptococcus gordonii, and Streptococcus mutans

The Journal of biological chemistry, 2001-07, Vol.276 (27), p.24511-24518

2001

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Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG‐positive prostate cancer

International journal of cancer, 2008-12, Vol.123 (12), p.2774-2781

2008

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Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity

Oncotarget, 2017-09, Vol.8 (43), p.73925-73937

2017

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Integrated in vivo genetic and pharmacologic screening identifies co-inhibition of EGRF and ROCK as a potential treatment regimen for triple-negative breast cancer

Oncotarget, 2016-07, Vol.7 (28), p.42859-42872

2016

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Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na

Molecular cancer therapeutics, 2014-05, Vol.13 (5), p.1054-1066

2014

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A high throughput profiling method for cutinolytic esterases

Enzyme and microbial technology, 2009-06, Vol.44 (6), p.394-399

2009

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Effects of Active Site Mutations on the Metal Binding Affinity, Catalytic Competence, and Stability of the Family II Pyrophosphatase from Bacillus subtilis

Biochemistry (Easton), 2005-03, Vol.44 (10), p.4004-4010

2005

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Ligand Binding Sites in Escherichia coli Inorganic Pyrophosphatase: Effects of Active Site Mutations

Biochemistry (Easton), 2001-04, Vol.40 (15), p.4645-4653

2001

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Structural and Functional Consequences of Substitutions at the Tyrosine 55−Lysine 104 Hydrogen Bond in Escherichia coli Inorganic Pyrophosphatase

Biochemistry (Easton), 1997-06, Vol.36 (25), p.7746-7753

1997

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Impact of minimal invasive extracorporeal circulation on the need of red blood cell transfusion

Perfusion, 2019-10, Vol.34 (7), p.605-612

2019

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Genome-Wide Dynamics of Nascent Noncoding RNA Transcription in Porcine Heart After Myocardial Infarction

Circulation. Cardiovascular genetics, 2017-06, Vol.10 (3)

2017

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Acute and Persistent Post-Craniotomy Pain: A Prospective 6-Month Follow-Up Questionnaire Study

Open Journal of Anesthesiology (Irvine, CA), 2023, Vol.13 (6), p.119-133

2023

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Spectral Entropy Parameters during Rapid Ventricular Pacing for Transcatheter Aortic Valve Implantation

Entropy (Basel, Switzerland), 2017-03, Vol.19 (3), p.133

2017

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Mixed Venous Oxygen Saturation during the Transcatheter Aortic Valve Replacement—A Prospective Cohort Study

Open Journal of Anesthesiology (Irvine, CA), 2019, Vol.9 (7), p.140-153

2019

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Vitamin D deficiency at admission is not associated with 90-day mortality in patients with severe sepsis or septic shock: Observational FINNAKI cohort study

Annals of medicine (Helsinki), 2016-01, Vol.48 (1-2), p.67-75

2016

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Transcriptomic and spatial dissection of human ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease

Cell reports. Medicine, 2024-05, Vol.5 (5), p.101556-101556, Article 101556

2024

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Topiramate add-on in treatment-resistant schizophrenia: a randomized, double-blind, placebo-controlled, crossover trial

The journal of clinical psychiatry, 2005-08, Vol.66 (8), p.1012

2005

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Urban wetland parks in Finland: improving water quality and creating endangered habitats

Ecosystems and people (Abingdon, England), 2015-01, Vol.11 (1), p.46-60

2015

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Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3

A Functional Genetic Screen Identifies the Phosphoinositide 3-kinase Pathway as a Determinant of Resistance to Fibroblast Growth Factor Receptor Inhibitors in FGFR Mutant Urothelial Cell Carcinoma

High-Throughput Cell-Based Screening of 4910 Known Drugs and Drug-like Small Molecules Identifies Disulfiram as an Inhibitor of Prostate Cancer Cell Growth

Identification of signalling cascades involved in red blood cell shrinkage and vesiculation

Language policies in Finland and Sweden: interdisciplinary and multi-sited comparisons

Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase

Quaternary Structure and Metal Ion Requirement of Family II Pyrophosphatases from Bacillus subtilis,Streptococcus gordonii, and Streptococcus mutans

Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG‐positive prostate cancer

Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity

Integrated in vivo genetic and pharmacologic screening identifies co-inhibition of EGRF and ROCK as a potential treatment regimen for triple-negative breast cancer

Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na

A high throughput profiling method for cutinolytic esterases

Effects of Active Site Mutations on the Metal Binding Affinity, Catalytic Competence, and Stability of the Family II Pyrophosphatase from Bacillus subtilis

Ligand Binding Sites in Escherichia coli Inorganic Pyrophosphatase: Effects of Active Site Mutations

Structural and Functional Consequences of Substitutions at the Tyrosine 55−Lysine 104 Hydrogen Bond in Escherichia coli Inorganic Pyrophosphatase

Impact of minimal invasive extracorporeal circulation on the need of red blood cell transfusion

Genome-Wide Dynamics of Nascent Noncoding RNA Transcription in Porcine Heart After Myocardial Infarction

Acute and Persistent Post-Craniotomy Pain: A Prospective 6-Month Follow-Up Questionnaire Study

Spectral Entropy Parameters during Rapid Ventricular Pacing for Transcatheter Aortic Valve Implantation

Mixed Venous Oxygen Saturation during the Transcatheter Aortic Valve Replacement—A Prospective Cohort Study

Vitamin D deficiency at admission is not associated with 90-day mortality in patients with severe sepsis or septic shock: Observational FINNAKI cohort study

Transcriptomic and spatial dissection of human ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease

Topiramate add-on in treatment-resistant schizophrenia: a randomized, double-blind, placebo-controlled, crossover trial

Urban wetland parks in Finland: improving water quality and creating endangered habitats

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