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Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors

Nature biotechnology, 2012-07, Vol.30 (7), p.715-720

2012

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An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum

Nature, 2007-07, Vol.448 (7150), p.200-203

2007

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Permeation Properties of a P2X Receptor in the Green Algae Ostreococcus tauri

The Journal of biological chemistry, 2008-05, Vol.283 (22), p.15122-15126

2008

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P2X receptor channels show threefold symmetry in ionic charge selectivity and unitary conductance

Nature neuroscience, 2011-01, Vol.14 (1), p.17-18

2011

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Molecular and functional variation in iPSC-derived sensory neurons

Nature genetics, 2018-01, Vol.50 (1), p.54-61

2018

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Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia

Science translational medicine, 2016-04, Vol.8 (335), p.335ra56

2016

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A small molecule CFTR potentiator restores ATP‐dependent channel gating to the cystic fibrosis mutant G551D‐CFTR

British journal of pharmacology, 2022-04, Vol.179 (7), p.1319-1337

2022

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GI‐530159, a novel, selective, mechanosensitive two‐pore‐domain potassium (K2P) channel opener, reduces rat dorsal root ganglion neuron excitability

British journal of pharmacology, 2018-06, Vol.175 (12), p.2272-2283

2018

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Characterizing Human Stem Cell–derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research

Molecular therapy, 2014-08, Vol.22 (8), p.1530-1543

2014

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Design and Identification of a Novel, Functionally Subtype Selective GABAA Positive Allosteric Modulator (PF-06372865)

Journal of medicinal chemistry, 2019-06, Vol.62 (12), p.5773-5796

2019

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Design and Identification of a Novel, Functionally Subtype Selective GABA A Positive Allosteric Modulator (PF-06372865)

Journal of medicinal chemistry, 2019-06, Vol.62 (12), p.5773, Article acs.jmedchem.9b00322

2019

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Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABAA receptor positive allosteric modulator PF‐06372865

British journal of pharmacology, 2018-02, Vol.175 (4), p.708-725

2018

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Influence of the N terminus on the biophysical properties and pharmacology of TREK1 potassium channels

Molecular pharmacology, 2014-05, Vol.85 (5), p.671-681

2014

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Publisher Correction: Molecular and functional variation in iPSC-derived sensory neurons

Nature genetics, 2019-07, Vol.51 (7), p.1190-1190

2019

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Investigation of the structure activity relationship of flufenamic acid derivatives at the human TRESK channel K2P18.1

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (20), p.4919-4924

2016

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Corrigendum to “Investigation of the structure activity relationship of flufenamic acid derivatives at the human TRESK channel K2P18.1” [Bioorg. Med. Chem. Lett. 26 (2016) 4919–4924]

Bioorganic & medicinal chemistry letters, 2017-05, Vol.27 (9), p.2082-2082

2017

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Investigation of the structure activity relationship of flufenamic acid derivatives at the human TRESK channel K 2P 18.1

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (20), p.4919-4924

2016

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Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABA A receptor positive allosteric modulator PF-06372865

British journal of pharmacology, 2018-02, Vol.175 (4), p.708-725

2018

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The Chimeric Approach Reveals That Differences in the TRPV1 Pore Domain Determine Species-specific Sensitivity to Block of Heat Activation

The Journal of biological chemistry, 2011-11, Vol.286 (45), p.39663-39672

2011

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Characterizing Human Stem Cell-derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research super(MT)Open

Molecular therapy, 2014-08, Vol.22 (8), p.1530-1543

2014

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P2X receptor channels show three-fold symmetry in ionic charge selectivity and unitary conductance

Nature neuroscience, 2010-12, Vol.14 (1), p.17-18

2010

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Thr 339 -to-Serine Substitution in Rat P2X 2 Receptor Second Transmembrane Domain Causes Constitutive Opening and Indicates a Gating Role for Lys 308

The Journal of neuroscience, 2007-11, Vol.27 (47), p.12916-12923

2007

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Thr super(339)-to-Serine Substitution in Rat P2X sub(2) Receptor Second Transmembrane Domain Causes Constitutive Opening and Indicates a Gating Role for Lys super(308)

The Journal of neuroscience, 2007-11, Vol.27 (47), p.12916-12923

2007

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Rescue of functional DeltaF508-CFTR channels by co-expression with truncated CFTR constructs in COS-1 cells

FEBS letters, 2003-11, Vol.554 (1-2), p.173-178

2003

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Chronic exposure to EGF affects trafficking and function of ENaC channel in cystic fibrosis cells

Biochemical and biophysical research communications, 2005-06, Vol.331 (2), p.503-511

2005

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Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors

An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum

Permeation Properties of a P2X Receptor in the Green Algae Ostreococcus tauri

P2X receptor channels show threefold symmetry in ionic charge selectivity and unitary conductance

Molecular and functional variation in iPSC-derived sensory neurons

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia

A small molecule CFTR potentiator restores ATP‐dependent channel gating to the cystic fibrosis mutant G551D‐CFTR

GI‐530159, a novel, selective, mechanosensitive two‐pore‐domain potassium (K2P) channel opener, reduces rat dorsal root ganglion neuron excitability

Characterizing Human Stem Cell–derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research

Design and Identification of a Novel, Functionally Subtype Selective GABAA Positive Allosteric Modulator (PF-06372865)

Design and Identification of a Novel, Functionally Subtype Selective GABA A Positive Allosteric Modulator (PF-06372865)

Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABAA receptor positive allosteric modulator PF‐06372865

Influence of the N terminus on the biophysical properties and pharmacology of TREK1 potassium channels

Publisher Correction: Molecular and functional variation in iPSC-derived sensory neurons

Investigation of the structure activity relationship of flufenamic acid derivatives at the human TRESK channel K2P18.1

Corrigendum to “Investigation of the structure activity relationship of flufenamic acid derivatives at the human TRESK channel K2P18.1” [Bioorg. Med. Chem. Lett. 26 (2016) 4919–4924]

Investigation of the structure activity relationship of flufenamic acid derivatives at the human TRESK channel K 2P 18.1

Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABA A receptor positive allosteric modulator PF-06372865

The Chimeric Approach Reveals That Differences in the TRPV1 Pore Domain Determine Species-specific Sensitivity to Block of Heat Activation

Characterizing Human Stem Cell-derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research super(MT)Open

P2X receptor channels show three-fold symmetry in ionic charge selectivity and unitary conductance

Thr 339 -to-Serine Substitution in Rat P2X 2 Receptor Second Transmembrane Domain Causes Constitutive Opening and Indicates a Gating Role for Lys 308

Thr super(339)-to-Serine Substitution in Rat P2X sub(2) Receptor Second Transmembrane Domain Causes Constitutive Opening and Indicates a Gating Role for Lys super(308)

Rescue of functional DeltaF508-CFTR channels by co-expression with truncated CFTR constructs in COS-1 cells

Chronic exposure to EGF affects trafficking and function of ENaC channel in cystic fibrosis cells

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