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Glial TDP‐43 and TDP‐43 induced glial pathology, focus on neurodegenerative proteinopathy syndromes

Glia, 2022-02, Vol.70 (2), p.239-255

2022

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Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing

Cell reports (Cambridge), 2020-06, Vol.31 (9), p.107719-107719, Article 107719

2020

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Molecular estimation of neurodegeneration pseudotime in older brains

Nature communications, 2020-11, Vol.11 (1), p.5781-5781, Article 5781

2020

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Loss of presenilin 2 age-dependently alters susceptibility to acute seizures and kindling acquisition

Neurobiology of disease, 2020-03, Vol.136, p.104719-104719, Article 104719

2020

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Author Correction: Molecular estimation of neurodegeneration pseudotime in older brains

Nature communications, 2020-12, Vol.11 (1), p.6307-6307, Article 6307

2020

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The p53 transcription factor modulates microglia behavior through microRNA-dependent regulation of c-Maf

The Journal of immunology (1950), 2014-01, Vol.192 (1), p.358-366

2014

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Advancements in high-resolution 3D microscopy analysis of endosomal morphology in postmortem Alzheimer's disease brains

Frontiers in neuroscience, 2024-01, Vol.17, p.1321680-1321680

2024

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Adipocyte-Derived Small Extracellular Vesicles from Patients with Alzheimer Disease Carry miRNAs Predicted to Target the CREB Signaling Pathway in Neurons

International journal of molecular sciences, 2023-09, Vol.24 (18), p.14024

2023

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Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort

Acta neuropathologica communications, 2019-06, Vol.7 (1), p.91-91, Article 91

2019

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Modulation of Hematopoietic Lineage Specification Impacts TREM2 Expression in Microglia-Like Cells Derived From Human Stem Cells

ASN neuro, 2017-08, Vol.9 (4), p.1759091417716610-1759091417716610

2017

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Spinal cord‐predominant neuropathology in an adult‐onset case of POLR3A‐related spastic ataxia

Neuropathology, 2022-02, Vol.42 (1), p.58-65

2022

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Presenilin 2 is the predominant γ-secretase in microglia and modulates cytokine release

PloS one, 2010-12, Vol.5 (12), p.e15743-e15743

2010

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Cerebrospinal fluid soluble insulin receptor levels in Alzheimer's disease

Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2024-04, Vol.16 (2), p.e12603-n/a

2024

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High Frequency of Concomitant Bladder, Bowel, and Sexual Symptoms in Huntington’s Disease: A Self-Reported Questionnaire Study

Journal of personalized medicine, 2021-07, Vol.11 (8), p.714

2021

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P142: Efficacy, safety and tolerability of chenodeoxycholic acid in adult patients with cerebrotendinous xanthomatosis (RESTORE): A randomized, placebo-controlled phase 3 study

Genetics in Medicine Open, 2024, Vol.2, p.101039, Article 101039

2024

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Hereditary ataxias: overview

Genetics in medicine, 2013-09, Vol.15 (9), p.673-683

2013

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R953C Mutation in SORL1 Gene Causes Functional Abnormality of the Protein

Alzheimer's & dementia, 2023-12, Vol.19 (S13), p.n/a

2023

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SOBA: Development and testing of a soluble oligomer binding assay for detection of amyloidogenic toxic oligomers

Proceedings of the National Academy of Sciences - PNAS, 2022-12, Vol.119 (50), p.e2213157119

2022

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Depletion of the AD risk gene SORL1 causes endo‐lysosomal dysfunction in human microglia

Alzheimer's & dementia, 2022-12, Vol.18 (S4), p.n/a

2022

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Lack Of APOE Christchurch Variant In Five Age Of Onset Outliers With PSEN1, PSEN2 Alzheimer Disease And MAPT Frontotemporal Dementia

Journal of the neurological sciences, 2020-09, Vol.418, p.117143-117143

2020

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Chronic seizures induce sex-specific cognitive deficits with loss of presenilin 2 function

Experimental neurology, 2023-03, Vol.361, p.114321-114321, Article 114321

2023

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A Review of the Familial Alzheimer’s Disease Locus PRESENILIN 2 and Its Relationship to PRESENILIN 1

Journal of Alzheimer's disease, 2018-01, Vol.66 (4), p.1323-1339

2018

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The pro‐inflammatory microRNA miR‐155 influences fibrillar β‐Amyloid1‐42 catabolism by microglia

Glia, 2021-07, Vol.69 (7), p.1736-1748

2021

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The glial response to CNS HIV infection includes p53 activation and increased expression of p53 target genes

Journal of neuroimmune pharmacology, 2007-12, Vol.2 (4), p.359-370

2007

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Chronic evoked seizures in young pre-symptomatic APP/PS1 mice induce serotonin changes and accelerate onset of Alzheimer’s disease-related neuropathology

Progress in neurobiology, 2024-04, Vol.235, p.102591-102591, Article 102591

2024

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Glial TDP‐43 and TDP‐43 induced glial pathology, focus on neurodegenerative proteinopathy syndromes

Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing

Molecular estimation of neurodegeneration pseudotime in older brains

Loss of presenilin 2 age-dependently alters susceptibility to acute seizures and kindling acquisition

Author Correction: Molecular estimation of neurodegeneration pseudotime in older brains

The p53 transcription factor modulates microglia behavior through microRNA-dependent regulation of c-Maf

Advancements in high-resolution 3D microscopy analysis of endosomal morphology in postmortem Alzheimer's disease brains

Adipocyte-Derived Small Extracellular Vesicles from Patients with Alzheimer Disease Carry miRNAs Predicted to Target the CREB Signaling Pathway in Neurons

Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort

Modulation of Hematopoietic Lineage Specification Impacts TREM2 Expression in Microglia-Like Cells Derived From Human Stem Cells

Spinal cord‐predominant neuropathology in an adult‐onset case of POLR3A‐related spastic ataxia

Presenilin 2 is the predominant γ-secretase in microglia and modulates cytokine release

Cerebrospinal fluid soluble insulin receptor levels in Alzheimer's disease

High Frequency of Concomitant Bladder, Bowel, and Sexual Symptoms in Huntington’s Disease: A Self-Reported Questionnaire Study

P142: Efficacy, safety and tolerability of chenodeoxycholic acid in adult patients with cerebrotendinous xanthomatosis (RESTORE): A randomized, placebo-controlled phase 3 study

Hereditary ataxias: overview

R953C Mutation in SORL1 Gene Causes Functional Abnormality of the Protein

SOBA: Development and testing of a soluble oligomer binding assay for detection of amyloidogenic toxic oligomers

Depletion of the AD risk gene SORL1 causes endo‐lysosomal dysfunction in human microglia

Lack Of APOE Christchurch Variant In Five Age Of Onset Outliers With PSEN1, PSEN2 Alzheimer Disease And MAPT Frontotemporal Dementia

Chronic seizures induce sex-specific cognitive deficits with loss of presenilin 2 function

A Review of the Familial Alzheimer’s Disease Locus PRESENILIN 2 and Its Relationship to PRESENILIN 1

The pro‐inflammatory microRNA miR‐155 influences fibrillar β‐Amyloid1‐42 catabolism by microglia

The glial response to CNS HIV infection includes p53 activation and increased expression of p53 target genes

Chronic evoked seizures in young pre-symptomatic APP/PS1 mice induce serotonin changes and accelerate onset of Alzheimer’s disease-related neuropathology

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