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A novel series of potent γ-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core

Bioorganic & medicinal chemistry letters, 2005-01, Vol.15 (2), p.373-378

2005

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Synthesis and γ-secretase activity of APP substrate-based hydroxyethylene dipeptide isosteres

Bioorganic & medicinal chemistry letters, 2003-01, Vol.13 (1), p.37-41

2003

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Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro

Neuroreport, 1998-09, Vol.9 (13), p.3053-3058

1998

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Cellular MTT reduction distinguishes the mechanism of action of β-amyloid from that of tachykinin receptor peptides

Neuropeptides (Edinburgh), 1996-04, Vol.30 (2), p.125-132

Shearman, M.S

1996

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Sulphated compounds attenuate β-amyloid toxicity by inhibiting its association with cells

Neuroreport, 1995-12, Vol.7 (1), p.49-53

1995

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Molecular analysis of the Lactococcus lactis sex factor

Developments in biological standardization, 1995, Vol.85, p.423

1995

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Inhibition of PC12 Cell Redox Activity is a Specific, Early Indicator of the Mechanism of β-Amyloid-Mediated Cell Death

Proceedings of the National Academy of Sciences - PNAS, 1994-02, Vol.91 (4), p.1470-1474

1994

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Haemopoietic stem cell development to neutrophils is associated with subcellular redistribution and differential expression of protein kinase C subspecies

Journal of cell science, 1993, Vol.104 (1), p.173-180

1993

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Synaptosomal Protein Kinase C Subspecies: B. Down‐Regulation Promoted by Phorbol Ester and Its Effect on Evoked Norepinephrine Release

Journal of neurochemistry, 1991-04, Vol.56 (4), p.1263-1269

1991

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Protein kinase C subspecies in adult rat hippocampal synaptosomes Activation by diacylglycerol and arachidonic acid

FEBS letters, 1991-02, Vol.279 (2), p.261-264

1991

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Protein kinase C activation enhances the delayed rectifier potassium current in guinea-pig heart cells

Journal of molecular and cellular cardiology, 1990-06, Vol.22 (6), p.725-734

1990

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MK-801, an excitatory amino acid antagonist, does not improve neurologic outcome following cardiac arrest in cats

Journal of cerebral blood flow and metabolism, 1989-12, Vol.9 (6), p.795

1989

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Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

FEBS letters, 1989-01, Vol.243 (2), p.177-182

1989

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Distinct cellular expression of beta I- and beta II-subspecies of protein kinase C in rat cerebellum

The Journal of neuroscience, 1988-10, Vol.8 (10), p.3850-3856

1988

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Guanine nucleotide effects on agonist binding to serotonin 5HT2 receptors in rat frontal cortex

Biochemical pharmacology, 1988-08, Vol.37 (16), p.3097-3102

1988

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The heterogeneity and differential expression of protein kinase C in nervous tissues

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 1988-07, Vol.320 (1199), p.313

1988

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Activation of a brain-specific protein kinase C subspecies in the presence of phosphatidylethanol

FEBS letters, 1988-04, Vol.231 (1), p.221-224

1988

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The common structure and activities of four subspecies of rat brain protein kinase C family

FEBS letters, 1987-11, Vol.223 (2), p.212-216

1987

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A novel series of potent γ-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core

Synthesis and γ-secretase activity of APP substrate-based hydroxyethylene dipeptide isosteres

Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro

Cellular MTT reduction distinguishes the mechanism of action of β-amyloid from that of tachykinin receptor peptides

Sulphated compounds attenuate β-amyloid toxicity by inhibiting its association with cells

Molecular analysis of the Lactococcus lactis sex factor

Inhibition of PC12 Cell Redox Activity is a Specific, Early Indicator of the Mechanism of β-Amyloid-Mediated Cell Death

Haemopoietic stem cell development to neutrophils is associated with subcellular redistribution and differential expression of protein kinase C subspecies

Synaptosomal Protein Kinase C Subspecies: B. Down‐Regulation Promoted by Phorbol Ester and Its Effect on Evoked Norepinephrine Release

Protein kinase C subspecies in adult rat hippocampal synaptosomes Activation by diacylglycerol and arachidonic acid

Protein kinase C activation enhances the delayed rectifier potassium current in guinea-pig heart cells

MK-801, an excitatory amino acid antagonist, does not improve neurologic outcome following cardiac arrest in cats

Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

Distinct cellular expression of beta I- and beta II-subspecies of protein kinase C in rat cerebellum

Guanine nucleotide effects on agonist binding to serotonin 5HT2 receptors in rat frontal cortex

The heterogeneity and differential expression of protein kinase C in nervous tissues

Activation of a brain-specific protein kinase C subspecies in the presence of phosphatidylethanol

The common structure and activities of four subspecies of rat brain protein kinase C family

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