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Effective elimination of dabigatran by haemodialysis. A phase I single-centre study in patients with end-stage renal disease

Thrombosis and haemostasis, 2013-04, Vol.109 (4), p.596-605

2013

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The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects

British journal of clinical pharmacology, 2007-09, Vol.64 (3), p.292-303

2007

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The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans

Drug metabolism and disposition, 2008-02, Vol.36 (2), p.386-399

2008

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Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model

Journal of thrombosis and haemostasis, 2012-09, Vol.10 (9), p.1841-1848

2012

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Development of benzimidazole derivatives as efficient matrices for the analysis of acidic small‐molecule compounds using matrix‐assisted laser desorption/ionisation time‐of‐flight mass spectrometry in negative ion mode

Rapid communications in mass spectrometry, 2024-07, Vol.38 (13), p.e9751-n/a

2024

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Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model

Critical care (London, England), 2014-01, Vol.18 (1), p.R27-R27

2014

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Use of Thromboelastography (TEG) for Detection of New Oral Anticoagulants

Archives of pathology & laboratory medicine (1976), 2015-05, Vol.139 (5), p.665-673

2015

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Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran

Blood coagulation & fibrinolysis, 2012-03, Vol.23 (2), p.138-143

2012

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Simultaneous determination of ledipasvir, sofosbuvir and its metabolite in rat plasma by UPLC–MS/MS and its application to a pharmacokinetic study

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016-01, Vol.1008, p.255-259

2016

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Nanoemulsion improves the oral absorption of candesartan cilexetil in rats: Performance and mechanism

Journal of controlled release, 2011-01, Vol.149 (2), p.168-174

2011

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Development and validation of a novel evaporation setup-assisted TLC method with fluorescence detection for determination of flibanserin in pharmaceutical and biological samples

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2022-04, Vol.1195, p.123204-123204, Article 123204

2022

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Routine coagulation assays underestimate levels of antithrombin‐dependent drugs but not of direct anticoagulant drugs in plasma from patients with cirrhosis

British journal of haematology, 2013-12, Vol.163 (5), p.666-673

2013

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Maribavir prophylaxis for prevention of cytomegalovirus infection in allogeneic stem cell transplant recipients: a multicenter, randomized, double-blind, placebo-controlled, dose-ranging study

Blood, 2008-06, Vol.111 (11), p.5403-5410

2008

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Bilastine vs. hydroxyzine: occupation of brain histamine H1‐receptors evaluated by positron emission tomography in healthy volunteers

British journal of clinical pharmacology, 2014-11, Vol.78 (5), p.970-980

2014

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Dabigatran Etexilate in Atrial Fibrillation Patients With Severe Renal Impairment: Dose Identification Using Pharmacokinetic Modeling and Simulation

Journal of clinical pharmacology, 2012-09, Vol.52 (9), p.1373-1378

2012

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Identification of a Human Whole Blood-Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo

The Journal of pharmacology and experimental therapeutics, 2021-03, Vol.376 (3), p.436-443

2021

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Effects of Maribavir on P‐Glycoprotein and CYP2D6 in Healthy Volunteers

Journal of clinical pharmacology, 2020-01, Vol.60 (1), p.96-106

2020

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Pharmacophore Identification and Scaffold Exploration to Discover Novel, Potent, and Chemically Stable Inhibitors of Acid Ceramidase in Melanoma Cells

Journal of medicinal chemistry, 2017-07, Vol.60 (13), p.5800-5815

2017

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Measurement of the direct oral anticoagulants apixaban, dabigatran, edoxaban, and rivaroxaban in human plasma using turbulent flow liquid chromatography with high-resolution mass spectrometry

Therapeutic drug monitoring, 2014-10, Vol.36 (5), p.597-605

2014

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Quantitative bio-analysis of pitavastatin and candesartan in rat plasma by HPLC-UV: Assessment of pharmacokinetic drug-drug interaction

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020-02, Vol.1138, p.121962, Article 121962

2020

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A Rapid and Sensitive Liquid Chromatography-Tandem Mass Spectrometry Bioanalytical Method for the Quantification of Encorafenib and Binimetinib as a First-Line Treatment for Advanced (Unresectable or Metastatic) Melanoma-Application to a Pharmacokinetic Study

Molecules (Basel, Switzerland), 2022-12, Vol.28 (1), p.79

2022

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Evaluation of coagulation assays versus LC-MS/MS for determinations of dabigatran concentrations in plasma

European journal of clinical pharmacology, 2013-11, Vol.69 (11), p.1875-1881

2013

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Transfer of Candesartan Into Human Breast Milk

Obstetrics and gynecology (New York. 1953), 2019-09, Vol.134 (3), p.481-484

2019

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Ultrasensitive spectrofluorimetric method for rapid determination of daclatasvir and ledipasvir in human plasma and pharmaceutical formulations

Journal of pharmaceutical and biomedical analysis, 2018-04, Vol.152, p.155-164

2018

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Prediction of Clinical Drug–Drug Interactions of Veliparib (ABT-888) with Human Renal Transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K)

Journal of pharmaceutical sciences, 2013-12, Vol.102 (12), p.4426-4432

2013

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Effective elimination of dabigatran by haemodialysis. A phase I single-centre study in patients with end-stage renal disease

The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects

The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans

Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model

Development of benzimidazole derivatives as efficient matrices for the analysis of acidic small‐molecule compounds using matrix‐assisted laser desorption/ionisation time‐of‐flight mass spectrometry in negative ion mode

Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model

Use of Thromboelastography (TEG) for Detection of New Oral Anticoagulants

Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran

Simultaneous determination of ledipasvir, sofosbuvir and its metabolite in rat plasma by UPLC–MS/MS and its application to a pharmacokinetic study

Nanoemulsion improves the oral absorption of candesartan cilexetil in rats: Performance and mechanism

Development and validation of a novel evaporation setup-assisted TLC method with fluorescence detection for determination of flibanserin in pharmaceutical and biological samples

Routine coagulation assays underestimate levels of antithrombin‐dependent drugs but not of direct anticoagulant drugs in plasma from patients with cirrhosis

Maribavir prophylaxis for prevention of cytomegalovirus infection in allogeneic stem cell transplant recipients: a multicenter, randomized, double-blind, placebo-controlled, dose-ranging study

Bilastine vs. hydroxyzine: occupation of brain histamine H1‐receptors evaluated by positron emission tomography in healthy volunteers

Dabigatran Etexilate in Atrial Fibrillation Patients With Severe Renal Impairment: Dose Identification Using Pharmacokinetic Modeling and Simulation

Identification of a Human Whole Blood-Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo

Effects of Maribavir on P‐Glycoprotein and CYP2D6 in Healthy Volunteers

Pharmacophore Identification and Scaffold Exploration to Discover Novel, Potent, and Chemically Stable Inhibitors of Acid Ceramidase in Melanoma Cells

Measurement of the direct oral anticoagulants apixaban, dabigatran, edoxaban, and rivaroxaban in human plasma using turbulent flow liquid chromatography with high-resolution mass spectrometry

Quantitative bio-analysis of pitavastatin and candesartan in rat plasma by HPLC-UV: Assessment of pharmacokinetic drug-drug interaction

A Rapid and Sensitive Liquid Chromatography-Tandem Mass Spectrometry Bioanalytical Method for the Quantification of Encorafenib and Binimetinib as a First-Line Treatment for Advanced (Unresectable or Metastatic) Melanoma-Application to a Pharmacokinetic Study

Evaluation of coagulation assays versus LC-MS/MS for determinations of dabigatran concentrations in plasma

Transfer of Candesartan Into Human Breast Milk

Ultrasensitive spectrofluorimetric method for rapid determination of daclatasvir and ledipasvir in human plasma and pharmaceutical formulations

Prediction of Clinical Drug–Drug Interactions of Veliparib (ABT-888) with Human Renal Transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K)

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