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Mechanisms of Camptothecin Resistance by Human Topoisomerase I Mutations

Applied physics letters, 2004-06, Vol.339 (4), p.773-784

2004

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Findings across pre-clinical models in the development of PT-112, a novel investigational platinum-pyrophosphate anti-cancer agent

European journal of cancer (1990), 2016-12, Vol.69, p.S153-S153

2016

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2594 Safety and efficacy of Temsirolimus (Torisel®) as second line treatment for patients with recurrent bladder cancer

European journal of cancer (1990), 2015-09, Vol.51, p.S509-S509

2015

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Development of a Double‐Antigen Microsphere Immunoassay for Simultaneous Group and Serotype Detection of Bluetongue Virus Antibodies

Transboundary and emerging diseases, 2017-12, Vol.64 (6), p.1837-1847

2017

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First detection and genome sequencing of SARS‐CoV‐2 in an infected cat in France

Transboundary and emerging diseases, 2020-11, Vol.67 (6), p.2324-2328

2020

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Induction of Topoisomerase I Cleavage Complexes by 1-β -D-Arabinofuranosylcytosine (ara-C) in vitro and in Ara-C-Treated Cells

Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (4), p.1885-1890

2000

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Characterization of a novel topoisomerase I mutation from a camptothecin-resistant human prostate cancer cell line

Cancer research (Chicago, Ill.), 2001-03, Vol.61 (5), p.1964-1969

2001

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Poisoning of Human DNA Topoisomerase I by Ecteinascidin 743, an Anticancer Drug That Selectively Alkylates DNA in the Minor Groove

Proceedings of the National Academy of Sciences - PNAS, 1999-06, Vol.96 (13), p.7196-7201

1999

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Broad spectrum reactivity versus subtype specificity—Trade-offs in serodiagnosis of influenza A virus infections by competitive ELISA

Journal of virological methods, 2011-04, Vol.173 (1), p.49-59

2011

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Benzo[a]pyrene Diol Epoxide Adducts in DNA Are Potent Suppressors of a Normal Topoisomerase I Cleavage Site and Powerful Inducers of other Topoisomerase I Cleavages

Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (5), p.2040-2045

2000

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Aclacinomycin A stabilizes topoisomerase I covalent complexes

Cancer research (Chicago, Ill.), 1997-10, Vol.57 (20), p.4564-4569

1997

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Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

BBA - Gene Structure and Expression, 1998-10, Vol.1400 (1), p.83-106

1998

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Topoisomerase I-mediated DNA damage

Advances in Cancer Research, 2001-01, Vol.80, p.189-216

2001

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The Chemistry of Wine Polyphenolic C-Glycosidic Ellagitannins Targeting Human Topoisomerase II

Chemistry : a European journal, 2005-11, Vol.11 (22), p.6503-6513

2005

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Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair

Nature Medicine, 2001-08, Vol.7 (8), p.961-966

2001

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Human DNA topoisomerase I-mediated cleavage and recombination of duck hepatitis B virus DNA in vitro

Nucleic acids research, 1999-04, Vol.27 (8), p.1919

1999

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467 - Findings across pre-clinical models in the development of PT-112, a novel investigational platinum-pyrophosphate anti-cancer agent

European journal of cancer (1990), 2016-12, Vol.69, p.S153-S153

2016

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Predicting drug response and toxicity based on gene polymorphisms

Critical reviews in oncology/hematology, 2005-06, Vol.54 (3), p.171-196

2005

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Deciphering the role of the ERCC2 gene polymorphism on anticancer drug sensitivity

Carcinogenesis (New York), 2012-05, Vol.33 (5), p.962-968

2012

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Gadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged Chromatin

Molecular and Cellular Biology, 1999-03, Vol.19 (3), p.1673-1685

1999

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Apoptotic Topoisomerase I-DNA Complexes Induced by Staurosporine-mediated Oxygen Radicals

The Journal of biological chemistry, 2004-11, Vol.279 (48), p.50499-50504

2004

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Topoisomerase I inhibitors: selectivity and cellular resistance

Drug resistance updates, 1999-10, Vol.2 (5), p.307-318

1999

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Gemcitabine (2′,2′-Difluoro-2′-Deoxycytidine), an Antimetabolite That Poisons Topoisomerase I

Clinical cancer research, 2002-08, Vol.8 (8), p.2499-2504

2002

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Topoisomerases I: new targets for the treatment of cancer and mechanisms of resistance

Bulletin du cancer, 1998-12, Vol.Spec No, p.5

1998

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Effects of Uracil Incorporation, DNA Mismatches, and Abasic Sites on Cleavage and Religation Activities of Mammalian Topoisomerase I

The Journal of biological chemistry, 1997-03, Vol.272 (12), p.7792-7796

1997

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Mechanisms of Camptothecin Resistance by Human Topoisomerase I Mutations

Findings across pre-clinical models in the development of PT-112, a novel investigational platinum-pyrophosphate anti-cancer agent

2594 Safety and efficacy of Temsirolimus (Torisel®) as second line treatment for patients with recurrent bladder cancer

Development of a Double‐Antigen Microsphere Immunoassay for Simultaneous Group and Serotype Detection of Bluetongue Virus Antibodies

First detection and genome sequencing of SARS‐CoV‐2 in an infected cat in France

Induction of Topoisomerase I Cleavage Complexes by 1-β -D-Arabinofuranosylcytosine (ara-C) in vitro and in Ara-C-Treated Cells

Characterization of a novel topoisomerase I mutation from a camptothecin-resistant human prostate cancer cell line

Poisoning of Human DNA Topoisomerase I by Ecteinascidin 743, an Anticancer Drug That Selectively Alkylates DNA in the Minor Groove

Broad spectrum reactivity versus subtype specificity—Trade-offs in serodiagnosis of influenza A virus infections by competitive ELISA

Benzo[a]pyrene Diol Epoxide Adducts in DNA Are Potent Suppressors of a Normal Topoisomerase I Cleavage Site and Powerful Inducers of other Topoisomerase I Cleavages

Aclacinomycin A stabilizes topoisomerase I covalent complexes

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

Topoisomerase I-mediated DNA damage

The Chemistry of Wine Polyphenolic C-Glycosidic Ellagitannins Targeting Human Topoisomerase II

Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair

Human DNA topoisomerase I-mediated cleavage and recombination of duck hepatitis B virus DNA in vitro

467 - Findings across pre-clinical models in the development of PT-112, a novel investigational platinum-pyrophosphate anti-cancer agent

Predicting drug response and toxicity based on gene polymorphisms

Deciphering the role of the ERCC2 gene polymorphism on anticancer drug sensitivity

Gadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged Chromatin

Apoptotic Topoisomerase I-DNA Complexes Induced by Staurosporine-mediated Oxygen Radicals

Topoisomerase I inhibitors: selectivity and cellular resistance

Gemcitabine (2′,2′-Difluoro-2′-Deoxycytidine), an Antimetabolite That Poisons Topoisomerase I

Topoisomerases I: new targets for the treatment of cancer and mechanisms of resistance

Effects of Uracil Incorporation, DNA Mismatches, and Abasic Sites on Cleavage and Religation Activities of Mammalian Topoisomerase I

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