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Application of encoded library technology (ELT) to a protein–protein interaction target: Discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists

Bioorganic & medicinal chemistry, 2014-04, Vol.22 (7), p.2353-2365

2014

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Discovery of soluble epoxide hydrolase inhibitors through DNA-encoded library technology (ELT)

Bioorganic & medicinal chemistry, 2021-07, Vol.41, p.116216-116216, Article 116216

2021

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Employing Photocatalysis for the Design and Preparation of DNA‐Encoded Libraries: A Case Study

Chemical record, 2021-04, Vol.21 (4), p.616-630

2021

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PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery

RSC medicinal chemistry, 2022-11, Vol.13 (11), p.1341-1349

2022

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Antiparasitic activities of novel, orally available fumagillin analogs

Bioorganic & medicinal chemistry letters, 2009-09, Vol.19 (17), p.5128-5131

2009

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In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor

Prostaglandins & other lipid mediators, 2013-07, Vol.104-105, p.25-31

2013

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Discovery of Potent and Selective Inhibitors for ADAMTS‑4 through DNA-Encoded Library Technology (ELT)

ACS medicinal chemistry letters, 2015-08, Vol.6 (8), p.888-893

2015

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Characterization of Specific N -α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library

ACS medicinal chemistry letters, 2020-06, Vol.11 (6), p.1175-1184

2020

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Discovery of Clinical Candidate GSK1842799 As a Selective S1P1 Receptor Agonist (Prodrug) for Multiple Sclerosis

ACS medicinal chemistry letters, 2013-10, Vol.4 (10), p.942-947

2013

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Exploring amino acids derivatives as potent, selective, and direct agonists of sphingosine-1-phosphate receptor subtype-1

Bioorganic & medicinal chemistry letters, 2013-01, Vol.23 (2), p.472-475

2013

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Metabolites of PPI-2458, a selective, irreversible inhibitor of methionine aminopeptidase-2: structure determination and in vivo activity

Drug metabolism and disposition, 2013-04, Vol.41 (4), p.814

2013

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Carbamate Analogues of Fumagillin as Potent, Targeted Inhibitors of Methionine Aminopeptidase-2

Journal of medicinal chemistry, 2009-12, Vol.52 (24), p.8047-8056

2009

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Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists

Bioorganic & medicinal chemistry letters, 2010-04, Vol.20 (8), p.2520-2524

2010

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Synthesis and evaluation of alkoxy-phenylamides and alkoxy-phenylimidazoles as potent sphingosine-1-phosphate receptor subtype-1 agonists

Bioorganic & medicinal chemistry letters, 2009-01, Vol.19 (2), p.369-372

2009

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Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonists

Bioorganic & medicinal chemistry letters, 2009-04, Vol.19 (8), p.2315-2319

2009

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Orally Active Fumagillin Analogues: Transformations of a Reactive Warhead in the Gastric Environment

ACS medicinal chemistry letters, 2013-04, Vol.4 (4), p.381-386

2013

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A Perspective on 30 Years of DNA-Encoded Chemistry

DNA-Encoded Libraries, 2022, Vol.40, p.259-276

2022

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Rapid Determination of Substrate Specificity of Clostridium histolyticum β-Collagenase Using an Immobilized Peptide Library

The Journal of biological chemistry, 2002-03, Vol.277 (10), p.8366-8371

2002

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Cover Picture: Employing Photocatalysis for the Design and Preparation of DNA‐Encoded Libraries: A Case Study (Chem. Rec. 4/2021)

Chemical record, 2021-04, Vol.21 (4), p.615-615

2021

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Mode of deactivation of the enkephalins by rat and human plasma and rat brain homogenates

Nature (London), 1976-08, Vol.262 (5571), p.782-783

1976

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Design, Synthesis, and Biological Activities of Potent and Selective Somatostatin Analogues Incorporating Novel Peptoid Residues

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2679-2685

1998

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Synthetic approaches to the ‘Azole’ peptide mimetics

Tetrahedron letters, 1993-03, Vol.34 (12), p.1901-1904

1993

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Application of encoded library technology (ELT) to a protein–protein interaction target: Discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists

Design, synthesis and selection of DNA-encoded small-molecule libraries

Discovery of soluble epoxide hydrolase inhibitors through DNA-encoded library technology (ELT)

Employing Photocatalysis for the Design and Preparation of DNA‐Encoded Libraries: A Case Study

PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery

Antiparasitic activities of novel, orally available fumagillin analogs

Discovery of Highly Potent and Selective Small Molecule ADAMTS‑5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT)

In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor

Discovery of Potent and Selective Inhibitors for ADAMTS‑4 through DNA-Encoded Library Technology (ELT)

Characterization of Specific N -α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library

Discovery, SAR, and X‑ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library

Discovery of Clinical Candidate GSK1842799 As a Selective S1P1 Receptor Agonist (Prodrug) for Multiple Sclerosis

Exploring amino acids derivatives as potent, selective, and direct agonists of sphingosine-1-phosphate receptor subtype-1

Metabolites of PPI-2458, a selective, irreversible inhibitor of methionine aminopeptidase-2: structure determination and in vivo activity

Carbamate Analogues of Fumagillin as Potent, Targeted Inhibitors of Methionine Aminopeptidase-2

Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists

Synthesis and evaluation of alkoxy-phenylamides and alkoxy-phenylimidazoles as potent sphingosine-1-phosphate receptor subtype-1 agonists

Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonists

Orally Active Fumagillin Analogues: Transformations of a Reactive Warhead in the Gastric Environment

A Perspective on 30 Years of DNA-Encoded Chemistry

Rapid Determination of Substrate Specificity of Clostridium histolyticum β-Collagenase Using an Immobilized Peptide Library

Cover Picture: Employing Photocatalysis for the Design and Preparation of DNA‐Encoded Libraries: A Case Study (Chem. Rec. 4/2021)

Mode of deactivation of the enkephalins by rat and human plasma and rat brain homogenates

Design, Synthesis, and Biological Activities of Potent and Selective Somatostatin Analogues Incorporating Novel Peptoid Residues

Synthetic approaches to the ‘Azole’ peptide mimetics

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