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Deep learning allows genome-scale prediction of Michaelis constants from structural features

PLoS biology, 2021-10, Vol.19 (10), p.e3001402-e3001402

2021

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A general model to predict small molecule substrates of enzymes based on machine and deep learning

Nature communications, 2023-05, Vol.14 (1), p.2787-2787, Article 2787

2023

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Correlating enzyme annotations with a large set of microbial growth temperatures reveals metabolic adaptations to growth at diverse temperatures

BMC microbiology, 2018-11, Vol.18 (1), p.177-177, Article 177

Engqvist, Martin K M

2018

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Experimental and computational investigation of enzyme functional annotations uncovers misannotation in the EC 1.1.3.15 enzyme class

PLoS computational biology, 2021-09, Vol.17 (9), p.e1009446-e1009446

2021

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Machine Learning Applied to Predicting Microorganism Growth Temperatures and Enzyme Catalytic Optima

ACS synthetic biology, 2019-06, Vol.8 (6), p.1411-1420

2019

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Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA

PLoS genetics, 2017-02, Vol.13 (2), p.e1006628-e1006628

2017

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Engineering Saccharomyces cerevisiae for the production and secretion of Affibody molecules

Microbial cell factories, 2022-03, Vol.21 (1), p.36-36, Article 36

2022

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The influence of alternative pathways of respiration that utilize branched‐chain amino acids following water shortage in Arabidopsis

Plant, cell and environment, 2016-06, Vol.39 (6), p.1304-1319

2016

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Directed evolution of a far-red fluorescent rhodopsin

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (36), p.13034-13039

2014

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A synthesis of bacterial and archaeal phenotypic trait data

Scientific data, 2020-06, Vol.7 (1), p.170-170, Article 170

2020

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Different Routes of Protein Folding Contribute to Improved Protein Production in Saccharomyces cerevisiae

mBio, 2020-11, Vol.11 (6), p.1

2020

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Directed Evolution of Gloeobacter violaceus Rhodopsin Spectral Properties

Journal of molecular biology, 2015-01, Vol.427 (1), p.205-220

2015

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Adaptation of a Microfluidic qPCR System for Enzyme Kinetic Studies

ACS omega, 2021-01, Vol.6 (3), p.1985-1990

2021

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Applications of Protein Engineering and Directed Evolution in Plant Research

Plant physiology (Bethesda), 2019-03, Vol.179 (3), p.907-917

2019

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3D‐Printed Phenacrylate Decarboxylase Flow Reactors for the Chemoenzymatic Synthesis of 4‐Hydroxystilbene

Chemistry : a European journal, 2019-12, Vol.25 (70), p.15998-16001

2019

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Learning deep representations of enzyme thermal adaptation

Protein science, 2022-12, Vol.31 (12), p.e4480-n/a

2022

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Expanding functional protein sequence spaces using generative adversarial networks

Nature machine intelligence, 2021-04, Vol.3 (4), p.324-333

2021

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Visualizing tomato spotted wilt virus protein localization: Cross-kingdom comparisons of protein-protein interactions

Molecular plant-microbe interactions, 2024-10

2024

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Chiral Alcohols from Alkenes and Water: Directed Evolution of a Styrene Hydratase

Angewandte Chemie International Edition, 2023-02, Vol.62 (7), p.e202215093-n/a

International ed. in English, 2023

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Synergistic neurotoxicity of opioids and human immunodeficiency virus-1 Tat protein in striatal neurons in vitro

Neuroscience, 2001-01, Vol.102 (3), p.555-563

2001

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ANT: Software for Generating and Evaluating Degenerate Codons for Natural and Expanded Genetic Codes

ACS synthetic biology, 2015-08, Vol.4 (8), p.935-938

2015

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Modeling‐Assisted Design of Thermostable Benzaldehyde Lyases from Rhodococcus erythropolis for Continuous Production of α‐Hydroxy Ketones

Chembiochem : a European journal of chemical biology, 2022-04, Vol.23 (7), p.e202100468-n/a

2022

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Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons

Nature communications, 2014-09, Vol.5 (1), p.4894-4894, Article 4894

2014

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Discovery of Two Novel Oxidases Using a High‐Throughput Activity Screen

Chembiochem : a European journal of chemical biology, 2022-01, Vol.23 (2), p.e202100510-n/a

2022

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d-Lactate dehydrogenase as a marker gene allows positive selection of transgenic plants

FEBS letters, 2012-01, Vol.586 (1), p.36-40

2012

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Deep learning allows genome-scale prediction of Michaelis constants from structural features

A general model to predict small molecule substrates of enzymes based on machine and deep learning

Correlating enzyme annotations with a large set of microbial growth temperatures reveals metabolic adaptations to growth at diverse temperatures

Experimental and computational investigation of enzyme functional annotations uncovers misannotation in the EC 1.1.3.15 enzyme class

Machine Learning Applied to Predicting Microorganism Growth Temperatures and Enzyme Catalytic Optima

Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA

Engineering Saccharomyces cerevisiae for the production and secretion of Affibody molecules

The influence of alternative pathways of respiration that utilize branched‐chain amino acids following water shortage in Arabidopsis

Directed evolution of a far-red fluorescent rhodopsin

A synthesis of bacterial and archaeal phenotypic trait data

Different Routes of Protein Folding Contribute to Improved Protein Production in Saccharomyces cerevisiae

Directed Evolution of Gloeobacter violaceus Rhodopsin Spectral Properties

Adaptation of a Microfluidic qPCR System for Enzyme Kinetic Studies

Applications of Protein Engineering and Directed Evolution in Plant Research

3D‐Printed Phenacrylate Decarboxylase Flow Reactors for the Chemoenzymatic Synthesis of 4‐Hydroxystilbene

Learning deep representations of enzyme thermal adaptation

Expanding functional protein sequence spaces using generative adversarial networks

Visualizing tomato spotted wilt virus protein localization: Cross-kingdom comparisons of protein-protein interactions

Chiral Alcohols from Alkenes and Water: Directed Evolution of a Styrene Hydratase

Synergistic neurotoxicity of opioids and human immunodeficiency virus-1 Tat protein in striatal neurons in vitro

ANT: Software for Generating and Evaluating Degenerate Codons for Natural and Expanded Genetic Codes

Modeling‐Assisted Design of Thermostable Benzaldehyde Lyases from Rhodococcus erythropolis for Continuous Production of α‐Hydroxy Ketones

Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons

Discovery of Two Novel Oxidases Using a High‐Throughput Activity Screen

d-Lactate dehydrogenase as a marker gene allows positive selection of transgenic plants

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