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Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations

Drug resistance updates, 2008-02, Vol.11 (1), p.32-50

2008

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Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo

Clinical cancer research, 2007-09, Vol.13 (17), p.5183-5194

2007

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Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy

Autophagy, 2008-01, Vol.4 (1), p.107-109

2008

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Rescue therapy for patients with anti-PD-1-refractory Merkel cell carcinoma: a multicenter, retrospective case series

Journal for immunotherapy of cancer, 2019-07, Vol.7 (1), p.170-5, Article 170

2019

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A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis

PloS one, 2009-03, Vol.4 (3), p.e5061

2009

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Pneumonitis in Patients Receiving Thoracic Radiotherapy and Osimertinib: A Multi-Institutional Study

JTO clinical and research reports, 2023-10, Vol.4 (10), p.100559-100559, Article 100559

2023

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Lung cancer in patients who have never smoked - an emerging disease

Nature reviews. Clinical oncology, 2024-02, Vol.21 (2), p.121-146

2024

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Machine learning for genetics-based classification and treatment response prediction in cancer of unknown primary

Nature medicine, 2023-08, Vol.29 (8), p.2057-2067

2023

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Landscape of pathogenic germline variants in patients with lung cancer

Journal of clinical oncology, 2022-08, Vol.40 (36_suppl), p.388570-388570

2022

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Publisher Correction: Machine learning for genetics-based classification and treatment response prediction in cancer of unknown primary

Nature medicine, 2024-02, Vol.30 (2), p.607-607

2024

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Hepatology (Baltimore, Md.), 2019-06, Vol.69 (6), p.2718-2719

2019

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Hepatology (Baltimore, Md.), 2019-06, Vol.69 (6), p.2718-2719

2019

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Hepatology (Baltimore, Md.), 2019-06, Vol.69 (6), p.2718-2719

2019

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Nodular Regenerative Hyperplasia Associated With Immune Checkpoint Blockade

Hepatology (Baltimore, Md.), 2018-12, Vol.68 (6), p.2431-2433

2018

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Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ

Biochemical journal, 2017-11, Vol.474 (23), p.3903-3914

2017

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Combining Nelfinavir With Chloroquine Inhibits In Vivo Growth of Human Lung Cancer Xenograft Tumors

In vivo (Athens), 2021-01, Vol.35 (1), p.141-145

2021

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Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer

The Journal of biological chemistry, 2015-12, Vol.290 (51), p.30390-30405

2015

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Targeting Akt in cancer therapy

Anti-cancer drugs, 2007-09, Vol.18 (8), p.861-874

2007

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Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity

Biochemical journal, 2015-07, Vol.469 (1), p.59-69

2015

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Identification of the Rab5 binding site in p110β: assays for PI3Kβ binding to Rab5

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1298, p.271

2015

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Hepatology (Baltimore, Md.), 2019-06, Vol.69 (6), p.2718

2019

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Hepatology (Baltimore, Md.), 2019-06, Vol.69 (6), p.2718-2719

2019

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Exceptional Response to Bromodomain and Extraterminal Domain Inhibitor Therapy With BMS-986158 in BRD4-NUTM1 NUT Carcinoma Harboring a BRD4 Splice Site Mutation

JCO precision oncology, 2023-06, Vol.7, p.e2200633

2023

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Assembly and structure of the p85a homodimer

LoPiccolo, Jaclyn

2015

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ProQuest

Rescue therapy for patients with antiPD-1-refractory Merkel cell carcinoma: a multicenter, retrospective case series

Journal for immunotherapy of cancer, 2019-12, Vol.7 (1)

2019

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Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations

Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo

Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy

Rescue therapy for patients with anti-PD-1-refractory Merkel cell carcinoma: a multicenter, retrospective case series

A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis

Pneumonitis in Patients Receiving Thoracic Radiotherapy and Osimertinib: A Multi-Institutional Study

Lung cancer in patients who have never smoked - an emerging disease

Machine learning for genetics-based classification and treatment response prediction in cancer of unknown primary

Landscape of pathogenic germline variants in patients with lung cancer

Publisher Correction: Machine learning for genetics-based classification and treatment response prediction in cancer of unknown primary

Reply

Reply

Reply

Nodular Regenerative Hyperplasia Associated With Immune Checkpoint Blockade

Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ

Combining Nelfinavir With Chloroquine Inhibits In Vivo Growth of Human Lung Cancer Xenograft Tumors

Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer

Targeting Akt in cancer therapy

Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity

Identification of the Rab5 binding site in p110β: assays for PI3Kβ binding to Rab5

Reply

Reply

Exceptional Response to Bromodomain and Extraterminal Domain Inhibitor Therapy With BMS-986158 in BRD4-NUTM1 NUT Carcinoma Harboring a BRD4 Splice Site Mutation

Assembly and structure of the p85a homodimer

Rescue therapy for patients with antiPD-1-refractory Merkel cell carcinoma: a multicenter, retrospective case series

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