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Epigenetic Silencing of HIV-1 by the Histone H3 Lysine 27 Methyltransferase Enhancer of Zeste 2

Journal of Virology, 2011-09, Vol.85 (17), p.9078-9089

2011

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Synthesis of Fluorinated Nucleosides/Nucleotides and Their Antiviral Properties

Molecules (Basel, Switzerland), 2024-05, Vol.29 (10), p.2390

2024

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Enantioselective Synthesis of β‑l‑5-[(E)‑2-Bromovinyl)-1-((2S,4S)‑2-(hydroxymethyl)-1,3-(dioxolane-4-yl) Uracil)] (l‑BHDU) via Chiral Pure l‑Dioxolane

Journal of organic chemistry, 2024-07, Vol.89 (13), p.9313-9321

2024

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Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies

PloS one, 2013-08, Vol.8 (8), p.e71196

2013

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Fluorinated nucleosides: Synthesis and biological implication

Journal of fluorine chemistry, 2008-09, Vol.129 (9), p.743-766

2008

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Synthesis of an Anti-hepatitis B Agent, 2′-Fluoro-6′-methylene-carbocyclic Adenosine (FMCA) and Its Phosphoramidate (FMCAP)

Journal of organic chemistry, 2019-01, Vol.84 (2), p.752-759

2019

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Synthesis of 2′-deoxy-2′-fluoro-2′-C-methyl spiro cyclopentyl carbocyclic uridine analog as potential inhibitors of HCV NS5B polymerase

Nucleosides, nucleotides & nucleic acids, 2020-02, Vol.39 (1-3), p.52-68

2020

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Probing the Molecular Mechanisms of AZT Drug Resistance Mediated by HIV-1 Reverse Transcriptase Using a Transient Kinetic Analysis

Biochemistry (Easton), 2003-07, Vol.42 (29), p.8831-8841

2003

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Dynamics of Subgenomic Hepatitis C Virus Replicon RNA Levels in Huh-7 Cells after Exposure to Nucleoside Antimetabolites

Journal of Virology, 2003-10, Vol.77 (19), p.10689-10694

2003

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Stereoselective Synthesis of 2′-Fluoro-6′-methylene Carbocyclic Adenosine via Vince Lactam

Journal of organic chemistry, 2014-05, Vol.79 (9), p.3917-3923

2014

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A Stereoselective Synthesis of 4′‐α‐Fluoro‐methyl Carbocyclic Nucleoside Analogs

ChemistrySelect (Weinheim), 2023-07, Vol.8 (26), p.n/a

2023

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Antiviral Nucleosides: Chiral Synthesis and Chemotherapy

Chu, C. K

1, 2003

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Synthesis of Novel Spiro[2.3]hexane Carbocyclic Nucleosides via Enzymatic Resolution

Organic letters, 2004-07, Vol.6 (15), p.2531-2534

2004

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Synthesis and Potent Anti-HIV Activity of l-3‘-Fluoro-2‘,3‘-Unsaturated Cytidine

Organic letters, 2001-12, Vol.3 (26), p.4177-4180

2001

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Blockade of Tetrahydrobiopterin Synthesis Protects Neurons after Transient Forebrain Ischemia in Rat: A Novel Role for the Cofactor

The Journal of neuroscience, 1999-02, Vol.19 (3), p.878-889

1999

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Repression of proinflammatory cytokine and inducible nitric oxide synthase (NOS2) gene expression in activated microglia by N-acetyl-O-methyldopamine: Protein kinase a-dependent mechanism

Glia, 2001-03, Vol.33 (4), p.324-333

2001

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Enantioselective Synthesis of β-l-5-(E)-2-Bromovinyl)-1-((2S,4S)-2-(hydroxymethyl)-1,3-(dioxolane-4-yl) Uracil) (l-BHDU) via Chiral Pure l-Dioxolane

Journal of organic chemistry, 2024-07, Vol.89 (13), p.9313

2024

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Metabolism of the Anti-Hepatitis C Virus Nucleoside β-d-N4-Hydroxycytidine in Different Liver Cells

Antimicrobial Agents and Chemotherapy, 2004-12, Vol.48 (12), p.4636-4642

2004

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Synthesis, biological evaluation and molecular modeling studies of N-benzyladenosine analogues as potential anti-toxoplasma agents

Biochemical pharmacology, 2007-05, Vol.73 (10), p.1558-1572

2007

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Asymmetric synthesis and biological evaluation of .beta.-L-(2R,5S)- and .alpha.-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential anti-HIV agents

Journal of medicinal chemistry, 1993-01, Vol.36 (2), p.181-195

1993

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Practical Synthesis of d- and l-2-Cyclopentenone and Their Utility for the Synthesis of Carbocyclic Antiviral Nucleosides against Orthopox Viruses (Smallpox, Monkeypox, and Cowpox Virus)

Journal of organic chemistry, 2003-11, Vol.68 (23), p.9012-9018

2003

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Synthesis of enantiomerically pure (2'R,5'S)-(-)-1-(2-hydroxymethyloxathiolan-5-yl)cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV)

Journal of organic chemistry, 1992-04, Vol.57 (8), p.2217-2219

1992

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L-nucleosides: antiviral activity and molecular mechanism

Current topics in medicinal chemistry, 2002-10, Vol.2 (10), p.1065-1086

2002

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L-.beta.-(2S,4S)- and L-.alpha.-(2S,4R)-dioxolanyl nucleosides as potential anti-HIV agents: asymmetric synthesis and structure-activity relationships

Journal of medicinal chemistry, 1993-03, Vol.36 (5), p.519-528

1993

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Enantiomeric synthesis of carbocyclic analogs of D - and L -6-azapyrimidine ribonucleosides

Canadian journal of chemistry, 2006-04, Vol.84 (4), p.748-754

2006

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Epigenetic Silencing of HIV-1 by the Histone H3 Lysine 27 Methyltransferase Enhancer of Zeste 2

Synthesis of Fluorinated Nucleosides/Nucleotides and Their Antiviral Properties

Enantioselective Synthesis of β‑l‑5-[(E)‑2-Bromovinyl)-1-((2S,4S)‑2-(hydroxymethyl)-1,3-(dioxolane-4-yl) Uracil)] (l‑BHDU) via Chiral Pure l‑Dioxolane

Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies

Fluorinated nucleosides: Synthesis and biological implication

Synthesis of an Anti-hepatitis B Agent, 2′-Fluoro-6′-methylene-carbocyclic Adenosine (FMCA) and Its Phosphoramidate (FMCAP)

Synthesis of 2′-deoxy-2′-fluoro-2′-C-methyl spiro cyclopentyl carbocyclic uridine analog as potential inhibitors of HCV NS5B polymerase

Probing the Molecular Mechanisms of AZT Drug Resistance Mediated by HIV-1 Reverse Transcriptase Using a Transient Kinetic Analysis

Dynamics of Subgenomic Hepatitis C Virus Replicon RNA Levels in Huh-7 Cells after Exposure to Nucleoside Antimetabolites

Stereoselective Synthesis of 2′-Fluoro-6′-methylene Carbocyclic Adenosine via Vince Lactam

A Stereoselective Synthesis of 4′‐α‐Fluoro‐methyl Carbocyclic Nucleoside Analogs

Antiviral Nucleosides: Chiral Synthesis and Chemotherapy

Synthesis of Novel Spiro[2.3]hexane Carbocyclic Nucleosides via Enzymatic Resolution

Synthesis and Potent Anti-HIV Activity of l-3‘-Fluoro-2‘,3‘-Unsaturated Cytidine

Blockade of Tetrahydrobiopterin Synthesis Protects Neurons after Transient Forebrain Ischemia in Rat: A Novel Role for the Cofactor

Repression of proinflammatory cytokine and inducible nitric oxide synthase (NOS2) gene expression in activated microglia by N-acetyl-O-methyldopamine: Protein kinase a-dependent mechanism

Enantioselective Synthesis of β-l-5-(E)-2-Bromovinyl)-1-((2S,4S)-2-(hydroxymethyl)-1,3-(dioxolane-4-yl) Uracil) (l-BHDU) via Chiral Pure l-Dioxolane

Metabolism of the Anti-Hepatitis C Virus Nucleoside β-d-N4-Hydroxycytidine in Different Liver Cells

Synthesis, biological evaluation and molecular modeling studies of N-benzyladenosine analogues as potential anti-toxoplasma agents

Asymmetric synthesis and biological evaluation of .beta.-L-(2R,5S)- and .alpha.-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential anti-HIV agents

Practical Synthesis of d- and l-2-Cyclopentenone and Their Utility for the Synthesis of Carbocyclic Antiviral Nucleosides against Orthopox Viruses (Smallpox, Monkeypox, and Cowpox Virus)

Synthesis of enantiomerically pure (2'R,5'S)-(-)-1-(2-hydroxymethyloxathiolan-5-yl)cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV)

L-nucleosides: antiviral activity and molecular mechanism

L-.beta.-(2S,4S)- and L-.alpha.-(2S,4R)-dioxolanyl nucleosides as potential anti-HIV agents: asymmetric synthesis and structure-activity relationships

Enantiomeric synthesis of carbocyclic analogs of D - and L -6-azapyrimidine ribonucleosides

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