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In vitro selection of Plasmodium falciparum drug-resistant parasite lines

Journal of antimicrobial chemotherapy, 2010-03, Vol.65 (3), p.390-398

2010

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Advances in Phytochemistry, Textile and Renewable Energy Research for Industrial Growth

1, 2022

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Towards an Understanding of the Mechanism of Pyrimethamine-Sulfadoxine Resistance in Plasmodium falciparum: Genotyping of Dihydrofolate Reductase and Dihydropteroate Synthase of Kenyan Parasites

Antimicrobial Agents and Chemotherapy, 2000-04, Vol.44 (4), p.991-996

2000

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The past, present and future of antifolates in the treatment of Plasmodium falciparum infection

Journal of antimicrobial chemotherapy, 2006-06, Vol.57 (6), p.1043-1054

NZILA, Alexis

2006

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Building Innovation Capabilities for Sustainable Industrialisation: Renewable Electrification in Developing Economies

1, 2022

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Advances in Phytochemistry, Textile and Renewable Energy Research for Industrial Growth : Proceedings of the International Conference of Phytochemistry, Textile and Renewable Energy for Sustainable development (ICPTRE 2020), August 12-14, Eldoret, Kenya (Edition 1)

2022

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Pyrimethamine–sulfadoxine resistance in Plasmodium falciparum: what next?

Trends in Parasitology, 2001-12, Vol.17 (12), p.582-588

2001

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Inhibitors of de novo folate enzymes in Plasmodium falciparum

Drug discovery today, 2006-10, Vol.11 (19), p.939-944

Nzila, Alexis

2006

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Preclinical drug evaluation system in the Plasmodium knowlesi baboon model of malaria: the methotrexate study

Journal of medical primatology, 2013-04, Vol.42 (2), p.62-70

2013

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Plasmodium berghei ANKA: Selection of resistance to piperaquine and lumefantrine in a mouse model

Experimental parasitology, 2009-07, Vol.122 (3), p.196-202

2009

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Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine

The American journal of tropical medicine and hygiene, 2014-10, Vol.91 (4), p.833-843

2014

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Therapeutic potential of folate uptake inhibition in Plasmodium falciparum

Trends in parasitology, 2004-03, Vol.20 (3), p.109-112

2004

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Kenyan Plasmodium falciparum Field Isolates: Correlation between Pyrimethamine and Chlorcycloguanil Activity In Vitro and Point Mutations in the Dihydrofolate Reductase Domain

Antimicrobial Agents and Chemotherapy, 1998-01, Vol.42 (1), p.164-169

1998

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The changing in vitro susceptibility pattern to pyrimethamine/sulfadoxine in Plasmodium falciparum field isolates from Kilifi, Kenya

The American journal of tropical medicine and hygiene, 2000-03, Vol.62 (3), p.396-401

2000

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The role of sequential administration of sulphadoxine/pyrimethamine following quinine in the treatment of severe falciparum malaria in children

Tropical medicine & international health, 2005-05, Vol.10 (5), p.484-488

2005

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Genetic diversity of Plasmodium falciparum parasites from Kenya is not affected by antifolate drug selection

International journal for parasitology, 2002-11, Vol.32 (12), p.1469-1476

2002

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Impact of folate supplementation on the efficacy of sulfadoxine/pyrimethamine in preventing malaria in pregnancy: the potential of 5-methyl-tetrahydrofolate

Journal of antimicrobial chemotherapy, 2014-02, Vol.69 (2), p.323-330

2014

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Update on the in vivo tolerance and in vitro reduced susceptibility to the antimalarial lumefantrine

Journal of antimicrobial chemotherapy, 2012-10, Vol.67 (10), p.2309-2315

2012

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Characteristics of Plasmodium falciparum dhfr Haplotypes That Confer Pyrimethamine Resistance, Kilifi, Kenya, 1987–2006

The Journal of infectious diseases, 2008-06, Vol.197 (12), p.1743-1751

2008

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Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy

Trends in parasitology, 2005-06, Vol.21 (6), p.292-298

2005

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Antimalarial activity of isoquine against Kenyan Plasmodium falciparum clinical isolates and association with polymorphisms in pfcrt and pfmdr1 genes

Journal of antimicrobial chemotherapy, 2013-04, Vol.68 (4), p.786-788

2013

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Plasmodium falciparum: in vitro activity of sulfadoxine and dapsone in field isolates from Kenya: point mutations in dihydropteroate synthase may not be the only determinants in sulfa resistance

Experimental parasitology, 2002-06, Vol.101 (2), p.90-96

2002

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Molecular Evidence of Greater Selective Pressure for Drug Resistance Exerted by the Long-Acting Antifolate Pyrimethamine/Sulfadoxine Compared with the Shorter-Acting Chlorproguanil/Dapsone on Kenyan Plasmodium falciparum

The Journal of infectious diseases, 2000-06, Vol.181 (6), p.2023-2028

2000

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Short report: association between chloroquine and amodiaquine resistance and allelic variation in the Plasmodium falciparum multiple drug resistance 1 gene and the chloroquine resistance transporter gene in isolates from the upper Nile in southern Sudan

The American journal of tropical medicine and hygiene, 2003-08, Vol.69 (2), p.184-187

2003

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Antimalarial chemotherapy: young guns or back to the future?

Trends in parasitology, 2003-11, Vol.19 (11), p.479-487

2003

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In vitro selection of Plasmodium falciparum drug-resistant parasite lines

Advances in Phytochemistry, Textile and Renewable Energy Research for Industrial Growth

Towards an Understanding of the Mechanism of Pyrimethamine-Sulfadoxine Resistance in Plasmodium falciparum: Genotyping of Dihydrofolate Reductase and Dihydropteroate Synthase of Kenyan Parasites

The past, present and future of antifolates in the treatment of Plasmodium falciparum infection

Building Innovation Capabilities for Sustainable Industrialisation: Renewable Electrification in Developing Economies

Advances in Phytochemistry, Textile and Renewable Energy Research for Industrial Growth : Proceedings of the International Conference of Phytochemistry, Textile and Renewable Energy for Sustainable development (ICPTRE 2020), August 12-14, Eldoret, Kenya (Edition 1)

Pyrimethamine–sulfadoxine resistance in Plasmodium falciparum: what next?

Inhibitors of de novo folate enzymes in Plasmodium falciparum

Preclinical drug evaluation system in the Plasmodium knowlesi baboon model of malaria: the methotrexate study

Plasmodium berghei ANKA: Selection of resistance to piperaquine and lumefantrine in a mouse model

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine

Therapeutic potential of folate uptake inhibition in Plasmodium falciparum

Kenyan Plasmodium falciparum Field Isolates: Correlation between Pyrimethamine and Chlorcycloguanil Activity In Vitro and Point Mutations in the Dihydrofolate Reductase Domain

The changing in vitro susceptibility pattern to pyrimethamine/sulfadoxine in Plasmodium falciparum field isolates from Kilifi, Kenya

The role of sequential administration of sulphadoxine/pyrimethamine following quinine in the treatment of severe falciparum malaria in children

Genetic diversity of Plasmodium falciparum parasites from Kenya is not affected by antifolate drug selection

Impact of folate supplementation on the efficacy of sulfadoxine/pyrimethamine in preventing malaria in pregnancy: the potential of 5-methyl-tetrahydrofolate

Update on the in vivo tolerance and in vitro reduced susceptibility to the antimalarial lumefantrine

Characteristics of Plasmodium falciparum dhfr Haplotypes That Confer Pyrimethamine Resistance, Kilifi, Kenya, 1987–2006

Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy

Antimalarial activity of isoquine against Kenyan Plasmodium falciparum clinical isolates and association with polymorphisms in pfcrt and pfmdr1 genes

Plasmodium falciparum: in vitro activity of sulfadoxine and dapsone in field isolates from Kenya: point mutations in dihydropteroate synthase may not be the only determinants in sulfa resistance

Molecular Evidence of Greater Selective Pressure for Drug Resistance Exerted by the Long-Acting Antifolate Pyrimethamine/Sulfadoxine Compared with the Shorter-Acting Chlorproguanil/Dapsone on Kenyan Plasmodium falciparum

Short report: association between chloroquine and amodiaquine resistance and allelic variation in the Plasmodium falciparum multiple drug resistance 1 gene and the chloroquine resistance transporter gene in isolates from the upper Nile in southern Sudan

Antimalarial chemotherapy: young guns or back to the future?

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