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The immunogenicity of humanized and fully human antibodies: Residual immunogenicity resides in the CDR regions

mAbs, 2010-05, Vol.2 (3), p.256-265

2010

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A β-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy

Molecular cancer therapeutics, 2005-11, Vol.4 (11), p.1791-1800

2005

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Design, creation and in vitro testing of a reduced immunogenicity humanized anti-CD25 monoclonal antibody that retains functional activity

Protein engineering, design and selection, 2019-12, Vol.32 (12), p.543-554

2019

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Murinization and H Chain Isotype Matching of the Anti-GITR Antibody DTA-1 Reduces Immunogenicity-Mediated Anaphylaxis in C57BL/6 Mice

The Journal of immunology (1950), 2017-06, Vol.198 (11), p.4502-4512

2017

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Antigen-specific human antibodies from mice comprising four distinct genetic modifications

Nature (London), 1994-04, Vol.368 (6474), p.856-859

1994

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Elimination of an immunodominant CD4+ T cell epitope in human IFN-beta does not result in an in vivo response directed at the subdominant epitope

The Journal of immunology (1950), 2004-06, Vol.172 (11), p.6658-6665

2004

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CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

Nature (London), 1992-04, Vol.356 (6370), p.607-609

1992

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Novel fluorochrome development enables 34-color high-content flow cytometry

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.159-159.1

2020

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Enhanced immunogenicity of a functional enzyme by T cell epitope modification

BMC immunology, 2002, Vol.3 (1), p.2-2, Article 2

2002

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An In Vitro Human Cell–Based Assay to Rank the Relative Immunogenicity of Proteins

Toxicological sciences, 2004-02, Vol.77 (2), p.280-289

2004

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Human population-based identification of CD4 + T-cell peptide epitope determinants

Journal of immunological methods, 2003-10, Vol.281 (1), p.95-108

2003

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Blockade of CD25 reduces regulatory T cell expansion and some manifestations of IL-2 mediated toxicity but does not improve anti-tumor efficacy in animal models of IL-2 immunotherapy

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.57-57.3

2018

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CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help

The Journal of experimental medicine, 1993-06, Vol.177 (6), p.1791-1796

1993

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Elimination of an Immunodominant CD4 super(+) T Cell Epitope in Human IFN- beta Does Not Result in an In Vivo Response Directed at the Subdominant Epitope

The Journal of immunology (1950), 2004-06, Vol.172 (11), p.6658-6665

2004

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A {szligbeta}-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy

Molecular cancer therapeutics, 2005-11, Vol.4 (11), p.1791-1800

2005

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Two distinct immunoglobulin heavy chain isotypes in a primitive, cartilaginous fish, Raja erinacea

Nucleic acids research, 1990-11, Vol.18 (21), p.6369-6376

1990

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Class Switching in Human Immunoglobulin Transgenic Mice

Annals of the New York Academy of Sciences, 1995-09, Vol.764 (1), p.536-546

1995

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Immunoglobulin heavy chain gene organization and complexity in the skate, Raja erinacea

Nucleic acids research, 1990-02, Vol.18 (4), p.1015-1020

1990

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Elimination of an Immunodominant CD4+ T Cell Epitope in Human IFN-{beta} Does Not Result in an In Vivo Response Directed at the Subdominant Epitope

The Journal of immunology (1950), 2004-06, Vol.172 (11), p.6658

2004

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MHC restriction of T-cell proliferative responses in Xenopus

Developmental and comparative immunology, 1993-09, Vol.17 (5), p.425-437

1993

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Teratogen metabolism: Thalidomide activation is mediated by cytochrome P-450

Toxicology and applied pharmacology, 1986, Vol.82 (1), p.175-179

1986

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Immune system activation associated with a naturally occurring infection in Xenopus laevis

Developmental and comparative immunology, 1992-11, Vol.16 (6), p.453-462

1992

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Tuning hardness in calcite by incorporation of amino acids

Nature materials, 2016-08, Vol.15 (8), p.903-910

2016

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Protocol for the development of a core outcome set for neonatal sepsis (NESCOS)

PloS one, 2023-12, Vol.18 (12), p.e0295325-e0295325

2023

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Additive manufactured biodegradable poly(glycerol sebacate methacrylate) nerve guidance conduits

Acta biomaterialia, 2018-09, Vol.78, p.48-63

2018

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The immunogenicity of humanized and fully human antibodies: Residual immunogenicity resides in the CDR regions

A β-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy

Design, creation and in vitro testing of a reduced immunogenicity humanized anti-CD25 monoclonal antibody that retains functional activity

Murinization and H Chain Isotype Matching of the Anti-GITR Antibody DTA-1 Reduces Immunogenicity-Mediated Anaphylaxis in C57BL/6 Mice

Antigen-specific human antibodies from mice comprising four distinct genetic modifications

Elimination of an immunodominant CD4+ T cell epitope in human IFN-beta does not result in an in vivo response directed at the subdominant epitope

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

Novel fluorochrome development enables 34-color high-content flow cytometry

Enhanced immunogenicity of a functional enzyme by T cell epitope modification

An In Vitro Human Cell–Based Assay to Rank the Relative Immunogenicity of Proteins

Human population-based identification of CD4 + T-cell peptide epitope determinants

Blockade of CD25 reduces regulatory T cell expansion and some manifestations of IL-2 mediated toxicity but does not improve anti-tumor efficacy in animal models of IL-2 immunotherapy

CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help

Elimination of an Immunodominant CD4 super(+) T Cell Epitope in Human IFN- beta Does Not Result in an In Vivo Response Directed at the Subdominant Epitope

A {szligbeta}-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy

Two distinct immunoglobulin heavy chain isotypes in a primitive, cartilaginous fish, Raja erinacea

Class Switching in Human Immunoglobulin Transgenic Mice

Immunoglobulin heavy chain gene organization and complexity in the skate, Raja erinacea

Elimination of an Immunodominant CD4+ T Cell Epitope in Human IFN-{beta} Does Not Result in an In Vivo Response Directed at the Subdominant Epitope

MHC restriction of T-cell proliferative responses in Xenopus

Teratogen metabolism: Thalidomide activation is mediated by cytochrome P-450

Immune system activation associated with a naturally occurring infection in Xenopus laevis

Tuning hardness in calcite by incorporation of amino acids

Protocol for the development of a core outcome set for neonatal sepsis (NESCOS)

Additive manufactured biodegradable poly(glycerol sebacate methacrylate) nerve guidance conduits

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