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Linear and Angular Heteroacenes from Double-Electrophilic Cyclization (DEC) and DEC-Reductive Elimination of Diynes

Organic letters, 2017-04, Vol.19 (8), p.1939-1941

2017

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Electrophilic Activation of P‑Alkynes in the Synthesis of P‑Substituted and P‑Centered Heterocycles

Journal of organic chemistry, 2016-05, Vol.81 (10), p.4012-4019

2016

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Polyynes to Polycycles: Domino Reactions Forming Polyfused Chalcogenophenes

Organic letters, 2020-04, Vol.22 (8), p.2987-2990

2020

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Attenuating PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate mediated collagen synthesis and hypertrophy in primary cardiac cells

The international journal of biochemistry & cell biology, 2021-05, Vol.134, p.105952-105952, Article 105952

2021

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Selective Synthesis of C1-Symmetric BINOL-phosphates and P-chiral Phosphoramides Using Directed ortho-Lithiation

Organic letters, 2021-09, Vol.23 (18), p.7055-7058

2021

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Selective Synthesis of C 1‑Symmetric BINOL-phosphates and P‑chiral Phosphoramides Using Directed ortho-Lithiation

Organic letters, 2021-09, Vol.23 (18), p.7055-7058

2021

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Alkyne Activation in the Diversity Oriented Synthesis of sp2‐Rich Scaffolds: A Biased Library Approach for Targeting Polynucleotides (DNA/RNA)

Chemistry : a European journal, 2022-12, Vol.28 (71), p.e202201925-n/a

2022

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Alkyne Activation in the Diversity Oriented Synthesis of sp 2 -Rich Scaffolds: A Biased Library Approach for Targeting Polynucleotides (DNA/RNA)

Chemistry : a European journal, 2022-12, Vol.28 (71), p.e202201925

2022

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Opposing Auxiliary Conformations Produce the Same Torquoselectivity in an Oxazolidinone-Directed Nazarov Cyclization

Journal of the American Chemical Society, 2013-06, Vol.135 (24), p.9156-9163

2013

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Mechanisms of Carbonyl Activation by BINOL N‑Triflylphosphoramides: Enantioselective Nazarov Cyclizations

ACS catalysis, 2017-05, Vol.7 (5), p.3466-3476

2017

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Formation of Highly Substituted Indenes through Acid Promoted Cyclodehydration with Nucleophile Incorporation

Journal of organic chemistry, 2019-03, Vol.84 (5), p.2756-2767

2019

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BNC210, a negative allosteric modulator of the alpha 7 nicotinic acetylcholine receptor, demonstrates anxiolytic- and antidepressant-like effects in rodents

Neuropharmacology, 2024-03, Vol.246, p.109836-109836, Article 109836

2024

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Multistereocenter-Containing Cyclopentanoids from Ynamides via Oxazolidinone-Controlled Nazarov Cyclization

Journal of organic chemistry, 2017-07, Vol.82 (13), p.6511-6527

2017

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Oxazolidinone-Promoted, Torquoselective Nazarov Cyclizations

Organic letters, 2012-04, Vol.14 (7), p.1732-1735

2012

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Synthesis of Thieno-Fused Heterocycles through Reiterative Iodocyclization

Advanced synthesis & catalysis, 2014-06, Vol.356 (9), p.1974-1978

2014

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Scaffold-Divergent Synthesis of Ring-Fused Indoles, Quinolines, and Quinolones via Iodonium-Induced Reaction Cascades

Journal of organic chemistry, 2013-05, Vol.78 (10), p.4708-4718

2013

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Iodine-Induced Reaction Cascades for the Rapid Construction of Variously Substituted Benzothiophenes

Organic letters, 2003-11, Vol.5 (23), p.4377-4380

2003

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From Sphingosine Kinase to Dihydroceramide Desaturase: A Structure–Activity Relationship (SAR) Study of the Enzyme Inhibitory and Anticancer Activity of 4‑((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol (SKI-II)

Journal of medicinal chemistry, 2016-02, Vol.59 (3), p.965-984

2016

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The role of dihydrosphingolipids in disease

Cellular and molecular life sciences : CMLS, 2019-03, Vol.76 (6), p.1107-1134

2019

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Asymmetric synthesis of multiple quaternary stereocentre-containing cyclopentyls by oxazolidinone-promoted Nazarov cyclizations

Chemical science (Cambridge), 2018, Vol.9 (20), p.4644-4649

2018

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Asymmetric Synthesis of (+)- and (−)-Pauciflorol F: Confirmation of Absolute Stereochemistry

Organic letters, 2013-08, Vol.15 (16), p.4118-4121

2013

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Sphingolipid imbalance and inflammatory effects induced by uremic toxins in heart and kidney cells are reversed by dihydroceramide desaturase 1 inhibition

Toxicology letters, 2021-10, Vol.350, p.133-142

2021

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Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties

Journal of medicinal chemistry, 2011-09, Vol.54 (17), p.6014-6027

2011

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Allosteric Modulators of the Adenosine A1 Receptor: Synthesis and Pharmacological Evaluation of 4-Substituted 2-Amino-3-benzoylthiophenes

Journal of medicinal chemistry, 2009-07, Vol.52 (14), p.4543-4547

2009

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Mapping the Interactions of I2, I., I−, and I+ with Alkynes and Their Roles in Iodocyclizations

Chemistry : a European journal, 2015-07, Vol.21 (28), p.10191-10199

2015

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Linear and Angular Heteroacenes from Double-Electrophilic Cyclization (DEC) and DEC-Reductive Elimination of Diynes

Electrophilic Activation of P‑Alkynes in the Synthesis of P‑Substituted and P‑Centered Heterocycles

Polyynes to Polycycles: Domino Reactions Forming Polyfused Chalcogenophenes

Attenuating PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate mediated collagen synthesis and hypertrophy in primary cardiac cells

Selective Synthesis of C1-Symmetric BINOL-phosphates and P-chiral Phosphoramides Using Directed ortho-Lithiation

Selective Synthesis of C 1‑Symmetric BINOL-phosphates and P‑chiral Phosphoramides Using Directed ortho-Lithiation

Alkyne Activation in the Diversity Oriented Synthesis of sp2‐Rich Scaffolds: A Biased Library Approach for Targeting Polynucleotides (DNA/RNA)

Alkyne Activation in the Diversity Oriented Synthesis of sp 2 -Rich Scaffolds: A Biased Library Approach for Targeting Polynucleotides (DNA/RNA)

Opposing Auxiliary Conformations Produce the Same Torquoselectivity in an Oxazolidinone-Directed Nazarov Cyclization

Mechanisms of Carbonyl Activation by BINOL N‑Triflylphosphoramides: Enantioselective Nazarov Cyclizations

Formation of Highly Substituted Indenes through Acid Promoted Cyclodehydration with Nucleophile Incorporation

BNC210, a negative allosteric modulator of the alpha 7 nicotinic acetylcholine receptor, demonstrates anxiolytic- and antidepressant-like effects in rodents

Multistereocenter-Containing Cyclopentanoids from Ynamides via Oxazolidinone-Controlled Nazarov Cyclization

Oxazolidinone-Promoted, Torquoselective Nazarov Cyclizations

Synthesis of Thieno-Fused Heterocycles through Reiterative Iodocyclization

Scaffold-Divergent Synthesis of Ring-Fused Indoles, Quinolines, and Quinolones via Iodonium-Induced Reaction Cascades

Iodine-Induced Reaction Cascades for the Rapid Construction of Variously Substituted Benzothiophenes

From Sphingosine Kinase to Dihydroceramide Desaturase: A Structure–Activity Relationship (SAR) Study of the Enzyme Inhibitory and Anticancer Activity of 4‑((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol (SKI-II)

The role of dihydrosphingolipids in disease

Asymmetric synthesis of multiple quaternary stereocentre-containing cyclopentyls by oxazolidinone-promoted Nazarov cyclizations

Asymmetric Synthesis of (+)- and (−)-Pauciflorol F: Confirmation of Absolute Stereochemistry

Sphingolipid imbalance and inflammatory effects induced by uremic toxins in heart and kidney cells are reversed by dihydroceramide desaturase 1 inhibition

Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties

Allosteric Modulators of the Adenosine A1 Receptor: Synthesis and Pharmacological Evaluation of 4-Substituted 2-Amino-3-benzoylthiophenes

Mapping the Interactions of I2, I., I−, and I+ with Alkynes and Their Roles in Iodocyclizations

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