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Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor

Molecular cancer therapeutics, 2008-07, Vol.7 (7), p.1880-1889

2008

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Oclacitinib ( APOQUEL ®) is a selective Janus kinase 1 inhibitor with efficacy in a canine model of flea allergic dermatitis

Journal of veterinary pharmacology and therapeutics, 2024-06

2024

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Speed of onset of a new chewable formulation of oclacitinib maleate (Apoquel®) in a canine model of IL‐31‐induced pruritus

Journal of veterinary pharmacology and therapeutics, 2022-07, Vol.45 (4), p.380-384

2022

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PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with EGFR and ERBB2 Mutations that Are Resistant to Gefitinib

Cancer research (Chicago, Ill.), 2007-12, Vol.67 (24), p.11924-11932

2007

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Cytokine transcriptome profiling in acute experimental canine atopic dermatitis skin lesions after IL‐31 inhibition with lokivetmab

Veterinary dermatology, 2023-08, Vol.34 (4), p.327-338

2023

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In Pursuit of an Allosteric Human Tropomyosin Kinase A (hTrkA) Inhibitor for Chronic Pain

ACS medicinal chemistry letters, 2021-11, Vol.12 (11), p.1847-1852

2021

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IL-31-induced pruritus in dogs: a novel experimental model to evaluate anti-pruritic effects of canine therapeutics

Veterinary dermatology, 2016-02, Vol.27 (1), p.34-e10

2016

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Serum concentrations of IL‐31 in dogs with nonpruritic mast cell tumours or lymphoma

Veterinary dermatology, 2020-12, Vol.31 (6), p.466-e124

2020

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Tyrosine Kinase Inhibitors. 19. 6-Alkynamides of 4-Anilinoquinazolines and 4-Anilinopyrido[3,4-d]pyrimidines as Irreversible Inhibitors of the erbB Family of Tyrosine Kinase Receptors

Journal of medicinal chemistry, 2006-02, Vol.49 (4), p.1475-1485

2006

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Induction of Apoptosis by Cationic Amphiphilic Drugs Amiodarone and Imipramine

Drug and chemical toxicology (New York, N.Y. 1978), 2005, Vol.28 (1), p.117-133

2005

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Interleukin‐31: its role in canine pruritus and naturally occurring canine atopic dermatitis

Veterinary dermatology, 2013-02, Vol.24 (1), p.48

2013

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G1 cell cycle arrest due to the inhibition of erbB family receptor tyrosine kinases does not require the retinoblastoma protein

Experimental cell research, 2005-02, Vol.303 (1), p.56-67

2005

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Induction of Apoptosis in Rat Peripheral Blood Lymphocytes by the Anticancer Drug CI‐994 (Acetyldinaline)

BioMed research international, 2001-01, Vol.1 (2), p.52-61

2001

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Kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-88204E

Biochemistry (Easton), 1993-07, Vol.32 (26), p.6548-6554

1993

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Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice

Carcinogenesis (New York), 1999-08, Vol.20 (8), p.1583-1590

1999

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Attenuation of G1 checkpoint function by the non-genotoxic carcinogen phenobarbital

Carcinogenesis (New York), 1998-07, Vol.19 (7), p.1173-1183

1998

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Chemical transformation of mouse liver cells results in altered cyclin D-CDK protein complexes

Carcinogenesis (New York), 1998-06, Vol.19 (6), p.1093-1102

1998

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The quinoline U-78036 is a potent inhibitor of HIV-1 reverse transcriptase

The Journal of biological chemistry, 1993-07, Vol.268 (20), p.14875-14880

1993

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Steady-state kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-87201E

The Journal of biological chemistry, 1993-03, Vol.268 (9), p.6119-6124

1993

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Kinetic studies with the non-nucleoside human immunodeficiency virus type-1 reverse transcriptase inhibitor U-90152E

Biochemical pharmacology, 1994-06, Vol.47 (11), p.2017-2028

1994

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Spare receptors and intrinsic activity: Studies with D1 dopamine receptor agonists

Synapse (New York, N.Y.), 1995-10, Vol.21 (2), p.177-187

1995

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Spare receptors and intrinsic activity: Studies with D 1 dopamine receptor agonists

Synapse (New York, N.Y.), 1995-10, Vol.21 (2), p.177-187

1995

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Regulation of apoptosis in mouse hepatocytes and alteration of apoptosis by nongenotoxic carcinogens

Cell growth & differentiation, 1998-09, Vol.9 (9), p.815-825

1998

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Interleukin‐31: Its Role in Canine Pruritus and Naturally Occurring Canine Atopic Dermatitis

Advances in Veterinary Dermatology, 2013, p.51-56

2013

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Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor

Oclacitinib ( APOQUEL ®) is a selective Janus kinase 1 inhibitor with efficacy in a canine model of flea allergic dermatitis

Speed of onset of a new chewable formulation of oclacitinib maleate (Apoquel®) in a canine model of IL‐31‐induced pruritus

PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with EGFR and ERBB2 Mutations that Are Resistant to Gefitinib

Cytokine transcriptome profiling in acute experimental canine atopic dermatitis skin lesions after IL‐31 inhibition with lokivetmab

Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4‑d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the Epidermal Growth Factor Receptor Family

In Pursuit of an Allosteric Human Tropomyosin Kinase A (hTrkA) Inhibitor for Chronic Pain

IL-31-induced pruritus in dogs: a novel experimental model to evaluate anti-pruritic effects of canine therapeutics

Serum concentrations of IL‐31 in dogs with nonpruritic mast cell tumours or lymphoma

Tyrosine Kinase Inhibitors. 19. 6-Alkynamides of 4-Anilinoquinazolines and 4-Anilinopyrido[3,4-d]pyrimidines as Irreversible Inhibitors of the erbB Family of Tyrosine Kinase Receptors

Induction of Apoptosis by Cationic Amphiphilic Drugs Amiodarone and Imipramine

Interleukin‐31: its role in canine pruritus and naturally occurring canine atopic dermatitis

G1 cell cycle arrest due to the inhibition of erbB family receptor tyrosine kinases does not require the retinoblastoma protein

Induction of Apoptosis in Rat Peripheral Blood Lymphocytes by the Anticancer Drug CI‐994 (Acetyldinaline)

Kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-88204E

Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice

Attenuation of G1 checkpoint function by the non-genotoxic carcinogen phenobarbital

Chemical transformation of mouse liver cells results in altered cyclin D-CDK protein complexes

The quinoline U-78036 is a potent inhibitor of HIV-1 reverse transcriptase

Steady-state kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-87201E

Kinetic studies with the non-nucleoside human immunodeficiency virus type-1 reverse transcriptase inhibitor U-90152E

Spare receptors and intrinsic activity: Studies with D1 dopamine receptor agonists

Spare receptors and intrinsic activity: Studies with D 1 dopamine receptor agonists

Regulation of apoptosis in mouse hepatocytes and alteration of apoptosis by nongenotoxic carcinogens

Interleukin‐31: Its Role in Canine Pruritus and Naturally Occurring Canine Atopic Dermatitis

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