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The NAD-dependent deacetylase SIRT2 is required for programmed necrosis

Nature (London), 2012-12, Vol.492 (7428), p.199-204

2012

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Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

The Journal of experimental medicine, 2011-03, Vol.208 (3), p.519-533

2011

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Second signals rescue B cells from activation-induced mitochondrial dysfunction and death

Nature immunology, 2018-08, Vol.19 (8), p.871-884

2018

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Characterization of the cardiac succinylome and its role in ischemia–reperfusion injury

Journal of molecular and cellular cardiology, 2015-11, Vol.88, p.73-81

2015

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Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation

Glia, 2018-11, Vol.66 (11), p.2427-2437

2018

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Cysteine 203 of Cyclophilin D Is Critical for Cyclophilin D Activation of the Mitochondrial Permeability Transition Pore

The Journal of biological chemistry, 2011-11, Vol.286 (46), p.40184-40192

2011

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Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects

The Journal of clinical investigation, 2015-12, Vol.125 (12), p.4592-4600

2015

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Boosting NAD+ blunts TLR4-induced type I IFN in control and systemic lupus erythematosus monocytes

The Journal of clinical investigation, 2022-03, Vol.132 (5), p.1-14

2022

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Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection

Frontiers in genetics, 2021-03, Vol.12, p.599261-599261

2021

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The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin Resistance

Endocrine reviews, 2010-02, Vol.31 (1), p.25-51

2010

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Immunometabolism at the Nexus of Cancer Therapeutic Efficacy and Resistance

Frontiers in immunology, 2021-05, Vol.12, p.657293

2021

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Loss of GCN5L1 in cardiac cells disrupts glucose metabolism and promotes cell death via reduced Akt/mTORC2 signaling

Biochemical journal, 2019-06, Vol.476 (12), p.1713-1724

2019

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Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling

Nature communications, 2021-05, Vol.12 (1), p.2745-12, Article 2745

2021

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Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

The Journal of experimental medicine, 2007-09, Vol.204 (9), p.2089-2102

2007

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Allele-specific mitochondrial stress induced by Multiple Mitochondrial Dysfunctions Syndrome 1 pathogenic mutations modeled in Caenorhabditis elegans

PLoS genetics, 2021-08, Vol.17 (8), p.e1009771-e1009771

2021

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The complementary and divergent roles of uncoupling proteins 1 and 3 in thermoregulation

The Journal of physiology, 2016-12, Vol.594 (24), p.7455-7464

2016

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Mitochondrial fidelity and metabolic agility control immune cell fate and function

The Journal of clinical investigation, 2018-09, Vol.128 (9), p.3651-3661

Sack, Michael N

2018

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Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting

Cell reports (Cambridge), 2024-02, Vol.43 (2), p.113700-113700, Article 113700

2024

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Targeting NAD+ Metabolism to Modulate Autoimmunity and Inflammation

The Journal of immunology (1950), 2024-04, Vol.212 (7), p.1043-1050

2024

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Parkin regulation of CHOP modulates susceptibility to cardiac endoplasmic reticulum stress

Scientific reports, 2017-05, Vol.7 (1), p.2093-12, Article 2093

2017

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Linking nutrient sensing, mitochondrial function, and PRR immune cell signaling in liver disease

Trends in immunology, 2022-11, Vol.43 (11), p.886-900

2022

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Myocardial Protection by Insulin at Reperfusion Requires Early Administration and Is Mediated via Akt and p70s6 Kinase Cell-Survival Signaling

Circulation research, 2001-12, Vol.89 (12), p.1191-1198

2001

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The endo-lysosomal regulatory protein BLOC1S1 modulates hepatic lysosomal content and lysosomal lipolysis

Biochemical and biophysical research communications, 2023-01, Vol.642, p.1-10

2023

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Generation of human induced pluripotential stem cells from individuals with complex heterozygous, isogenic corrected, and homozygous Bloc1s1 mutations

Stem cell research, 2022-10, Vol.64, p.102905-102905, Article 102905

2022

Volltextzugriff (PDF)

The enigma of anti-inflammatory therapy for the management of heart failure

Cardiovascular research, 2020-01, Vol.116 (1), p.6-8

Sack, Michael N

2020

Volltextzugriff (PDF)

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The NAD-dependent deacetylase SIRT2 is required for programmed necrosis

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

Second signals rescue B cells from activation-induced mitochondrial dysfunction and death

Characterization of the cardiac succinylome and its role in ischemia–reperfusion injury

Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation

Cysteine 203 of Cyclophilin D Is Critical for Cyclophilin D Activation of the Mitochondrial Permeability Transition Pore

Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects

Boosting NAD+ blunts TLR4-induced type I IFN in control and systemic lupus erythematosus monocytes

Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection

The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin Resistance

Immunometabolism at the Nexus of Cancer Therapeutic Efficacy and Resistance

Loss of GCN5L1 in cardiac cells disrupts glucose metabolism and promotes cell death via reduced Akt/mTORC2 signaling

Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling

Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

Allele-specific mitochondrial stress induced by Multiple Mitochondrial Dysfunctions Syndrome 1 pathogenic mutations modeled in Caenorhabditis elegans

The complementary and divergent roles of uncoupling proteins 1 and 3 in thermoregulation

Mitochondrial fidelity and metabolic agility control immune cell fate and function

Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting

Targeting NAD+ Metabolism to Modulate Autoimmunity and Inflammation

Parkin regulation of CHOP modulates susceptibility to cardiac endoplasmic reticulum stress

Linking nutrient sensing, mitochondrial function, and PRR immune cell signaling in liver disease

Myocardial Protection by Insulin at Reperfusion Requires Early Administration and Is Mediated via Akt and p70s6 Kinase Cell-Survival Signaling

The endo-lysosomal regulatory protein BLOC1S1 modulates hepatic lysosomal content and lysosomal lipolysis

Generation of human induced pluripotential stem cells from individuals with complex heterozygous, isogenic corrected, and homozygous Bloc1s1 mutations

The enigma of anti-inflammatory therapy for the management of heart failure

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