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Systemic and Ocular Safety of Intravitreal Anti-VEGF Therapies for Ocular Neovascular Disease

Survey of ophthalmology, 2011-03, Vol.56 (2), p.95-113

Tolentino, Michael, MD

2011

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Investigational drugs in clinical trials for macular degeneration

Expert opinion on investigational drugs, 2022-10, Vol.31 (10), p.1067-1085

2022

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Drugs in Phase II clinical trials for the treatment of age-related macular degeneration

Expert opinion on investigational drugs, 2015-02, Vol.24 (2), p.183-199

2015

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Sialic Acid Mimetic Microglial Sialic Acid-Binding Immunoglobulin-like Lectin Agonism: Potential to Restore Retinal Homeostasis and Regain Visual Function in Age-Related Macular Degeneration

Pharmaceuticals (Basel, Switzerland), 2023-12, Vol.16 (12), p.1735

2023

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Current and investigational drugs for the treatment of diabetic retinopathy

Expert opinion on investigational drugs, 2016-09, Vol.25 (9), p.1011-1022

2016

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Results of the 2-Year Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole (OASIS) Randomized Trial

Ophthalmology (Rochester, Minn.), 2016-10, Vol.123 (10), p.2232-2247

2016

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Comprehensive Ocular and Systemic Safety Evaluation of Polysialic Acid-Decorated Immune Modulating Therapeutic Nanoparticles (PolySia-NPs) to Support Entry into First-in-Human Clinical Trials

Pharmaceuticals (Basel, Switzerland), 2024-04, Vol.17 (4), p.481

2024

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Current molecular understanding and future treatment strategies for pathologic ocular neovascularization

Current molecular medicine, 2009-11, Vol.9 (8), p.973-981

Tolentino, Michael J

2009

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Challenges of selecting pharmacotherapy for macular edema the need for better and combination therapies

Expert opinion on pharmacotherapy, 2019-03, Vol.20 (4), p.373-377

2019

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Long-term Benefit of Sustained-Delivery Fluocinolone Acetonide Vitreous Inserts for Diabetic Macular Edema

Ophthalmology (Rochester, Minn.), 2011-04, Vol.118 (4), p.626-635.e2

2011

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PolySialic Acid Nanoparticles Actuate Complement-Factor-H-Mediated Inhibition of the Alternative Complement Pathway: A Safer Potential Therapy for Age-Related Macular Degeneration

Pharmaceuticals (Basel, Switzerland), 2024-04, Vol.17 (4), p.517

2024

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The DA VINCI Study: Phase 2 Primary Results of VEGF Trap-Eye in Patients with Diabetic Macular Edema

Ophthalmology (Rochester, Minn.), 2011-09, Vol.118 (9), p.1819-1826

2011

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Treatment of Diabetic Macular Edema with an Inhibitor of Vascular Endothelial-Protein Tyrosine Phosphatase That Activates Tie2

Ophthalmology (Rochester, Minn.), 2015-03, Vol.122 (3), p.545-554

2015

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PolySialic acid-nanoparticles inhibit macrophage mediated inflammation through Siglec agonism: a potential treatment for age related macular degeneration

Frontiers in immunology, 2023, Vol.14, p.1237016-1237016

2023

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Safety of Intravitreal Ocriplasmin for Focal Vitreomacular Adhesion in Patients with Exudative Age-Related Macular Degeneration

Ophthalmology (Rochester, Minn.), 2015-04, Vol.122 (4), p.796-802

2015

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SCORE Study Report #11: Incidences of Neovascular Events in Eyes with Retinal Vein Occlusion

Ophthalmology (Rochester, Minn.), 2011-07, Vol.118 (7), p.1364-1372

2011

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Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model

Molecular vision, 2003-05, Vol.9, p.210-216

2003

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Pathologic features of vascular endothelial growth factor-induced retinopathy in the nonhuman primate

American journal of ophthalmology, 2002-03, Vol.133 (3), p.373-385

2002

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Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a nonhuman primate, laser-induced model of choroidal neovascularization

Retina (Philadelphia, Pa.), 2004-02, Vol.24 (1), p.132-138

2004

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Inhibition of Retinal Neovascularization by Intraocular Viral-Mediated Delivery of Anti-angiogenic Agents

Molecular therapy, 2002-10, Vol.6 (4), p.490-494

2002

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Systemic rapamycin inhibits retinal and choroidal neovascularization in mice

Molecular vision, 2004-12, Vol.10, p.964-972

2004

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Pharmacological Regulation of Protein Expression from Adeno-Associated Viral Vectors in the Eye

Molecular therapy, 2002-08, Vol.6 (2), p.238-242

2002

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Intravitreous Injections of Vascular Endothelial Growth Factor Produce Retinal Ischemia and Microangiopathy in an Adult Primate

Ophthalmology (Rochester, Minn.), 1996-11, Vol.103 (11), p.1820-1828

1996

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SAT-444 Large-scale community outreach Fibroscan program to detect advanced fibrosis and cirrhosis for early detection of liver cancer

Journal of hepatology, 2024-06, Vol.80, p.S646-S646

2024

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Long-term Outcomes of Adding Lutein/Zeaxanthin and ω-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28

JAMA ophthalmology, 2022-07, Vol.140 (7), p.692

2022

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Systemic and Ocular Safety of Intravitreal Anti-VEGF Therapies for Ocular Neovascular Disease

Investigational drugs in clinical trials for macular degeneration

Drugs in Phase II clinical trials for the treatment of age-related macular degeneration

Sialic Acid Mimetic Microglial Sialic Acid-Binding Immunoglobulin-like Lectin Agonism: Potential to Restore Retinal Homeostasis and Regain Visual Function in Age-Related Macular Degeneration

Current and investigational drugs for the treatment of diabetic retinopathy

Results of the 2-Year Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole (OASIS) Randomized Trial

Comprehensive Ocular and Systemic Safety Evaluation of Polysialic Acid-Decorated Immune Modulating Therapeutic Nanoparticles (PolySia-NPs) to Support Entry into First-in-Human Clinical Trials

Current molecular understanding and future treatment strategies for pathologic ocular neovascularization

Challenges of selecting pharmacotherapy for macular edema the need for better and combination therapies

Long-term Benefit of Sustained-Delivery Fluocinolone Acetonide Vitreous Inserts for Diabetic Macular Edema

PolySialic Acid Nanoparticles Actuate Complement-Factor-H-Mediated Inhibition of the Alternative Complement Pathway: A Safer Potential Therapy for Age-Related Macular Degeneration

The DA VINCI Study: Phase 2 Primary Results of VEGF Trap-Eye in Patients with Diabetic Macular Edema

Treatment of Diabetic Macular Edema with an Inhibitor of Vascular Endothelial-Protein Tyrosine Phosphatase That Activates Tie2

PolySialic acid-nanoparticles inhibit macrophage mediated inflammation through Siglec agonism: a potential treatment for age related macular degeneration

Safety of Intravitreal Ocriplasmin for Focal Vitreomacular Adhesion in Patients with Exudative Age-Related Macular Degeneration

SCORE Study Report #11: Incidences of Neovascular Events in Eyes with Retinal Vein Occlusion

Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model

Pathologic features of vascular endothelial growth factor-induced retinopathy in the nonhuman primate

Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a nonhuman primate, laser-induced model of choroidal neovascularization

Inhibition of Retinal Neovascularization by Intraocular Viral-Mediated Delivery of Anti-angiogenic Agents

Systemic rapamycin inhibits retinal and choroidal neovascularization in mice

Pharmacological Regulation of Protein Expression from Adeno-Associated Viral Vectors in the Eye

Intravitreous Injections of Vascular Endothelial Growth Factor Produce Retinal Ischemia and Microangiopathy in an Adult Primate

SAT-444 Large-scale community outreach Fibroscan program to detect advanced fibrosis and cirrhosis for early detection of liver cancer

Long-term Outcomes of Adding Lutein/Zeaxanthin and ω-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28

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