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Immune Checkpoint LAG3 and Its Ligand FGL1 in Cancer

Frontiers in immunology, 2022-01, Vol.12, p.785091-785091

2022

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Pharmacokinetics, hepatic disposition, and heart tissue distribution of 14 compounds in rat after oral administration of Qi‐Li‐Qiang‐Xin capsule via ultra‐high‐performance liquid chromatography coupled with triple quadrupole tandem mass spectrometry

Journal of separation science, 2022-07, Vol.45 (13), p.2177-2189

2022

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An integrated strategy by absorbed component characterization, pharmacokinetics, and activity evaluation for identification of potential nephroprotective substances in Zhu‐Ling decoction

Journal of separation science, 2023-09, Vol.46 (17), p.e2300331-n/a

2023

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The Proliferative Role of Immune Checkpoints in Tumors: Double Regulation

Cancers, 2022-10, Vol.14 (21), p.5374

2022

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Chemical and metabolic profiling of Codonopsis Radix extract with an integrated strategy using ultra‐high‐performance liquid chromatography coupled with mass spectrometry

Journal of separation science, 2023-01, Vol.46 (2), p.e2200723-n/a

2023

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Clinical Research on the Mechanisms Underlying Immune Checkpoints and Tumor Metastasis

Frontiers in oncology, 2021-07, Vol.11, p.693321-693321

2021

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Dual immunological and proliferative regulation of immune checkpoint FGL1 in lung adenocarcinoma: The pivotal role of the YY1–FGL1–MYH9 axis

Frontiers in immunology, 2022-10, Vol.13, p.1014053-1014053

2022

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An integrated strategy by chemical characterization, in vivo metabolism, chemical isolation, and activity evaluation to target discovery of potential active substances in traditional Chinese medicine: Mori Fructus as an example

Arabian journal of chemistry, 2023-07, Vol.16 (7), p.104858, Article 104858

2023

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Characterization of chemical components of Periplocae Cortex and their metabolites in rats using ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry

Biomedical chromatography, 2020-04, Vol.34 (4), p.e4807-n/a

2020

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IGSF11 and VISTA: a pair of promising immune checkpoints in tumor immunotherapy

Biomarker research, 2022-07, Vol.10 (1), p.1-49, Article 49

2022

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Biotransformation and metabolic profile of Xian‐Ling‐Gu‐Bao capsule, a traditional Chinese medicine prescription, with rat intestinal microflora by ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight tandem mass spectrometry analysis

Biomedical chromatography, 2018-04, Vol.32 (4), p.n/a

2018

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A novel strategy with in vivo characterization, extraction, isolation and activity evaluation for discovery of absorbed anti-inflammatory oligosaccharides from Zhu-Ling decoction

Carbohydrate polymers, 2024-10, Vol.342, p.122422, Article 122422

2024

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A new strategy for discovering effective substances and mechanisms of traditional Chinese medicine based on standardized drug containing plasma and the absorbed ingredients composition, a case study of Xian-Ling-Gu-Bao capsules

Journal of ethnopharmacology, 2021-10, Vol.279, p.114396, Article 114396

2021

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Effects of Xian-Ling-Gu-Bao capsule on the gut microbiota in ovariectomized rats: Metabolism and modulation

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2021-06, Vol.1176, p.122771-122771, Article 122771

2021

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A combination of representative compounds, metabolism platform and diagnostic extraction strategy for characterization of metabolites of Shuang-Huang-Lian oral liquid in vivo by ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2018-06, Vol.155, p.216-234

2018

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Sweroside promotes osteoblastic differentiation and mineralization via interaction of membrane estrogen receptor-α and GPR30 mediated p38 signalling pathway on MC3T3-E1 cells

Phytomedicine (Stuttgart), 2020-03, Vol.68, p.153146-153146, Article 153146

2020

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Simultaneous determination of multiple components in rat plasma and pharmacokinetic studies at a pharmacodynamic dose of Xian-Ling-Gu-Bao capsule by UPLC-MS/MS

Journal of pharmaceutical and biomedical analysis, 2020-01, Vol.177, p.112836, Article 112836

2020

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An UHPLC-MS/MS method for simultaneous determination of ten sex steroid hormones in ovariectomy-induced osteoporosis rat and its application in discovery of sex steroid hormones regulatory components of Xian-Ling-Gu-Bao capsule

Journal of pharmaceutical and biomedical analysis, 2021-02, Vol.195, p.113888-113888, Article 113888

2021

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Systematic screening and characterization of Qi-Li-Qiang-Xin capsule-related xenobiotics in rats by ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018-07, Vol.1090, p.56-64

2018

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Identification and characterization of chemical constituents in Qi-Lin pills and their metabolites in rat bio-samples after oral administration using ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2020-09, Vol.188, p.113402-113402, Article 113402

2020

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Simultaneous determination of multiple constituents of Qi-Lin pill by UPLC-MS/MS: Applications to pharmacokinetics and testicular tissue distribution in rats

Journal of pharmaceutical and biomedical analysis, 2023-01, Vol.223, p.115157-115157, Article 115157

2023

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The downregulation of fibrinogen-like protein 1 inhibits the proliferation of lung adenocarcinoma via regulating MYC-target genes

Translational lung cancer research, 2022-03, Vol.11 (3), p.404-419

2022

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Simultaneous Quantitative Analysis of Multiple Biotransformation Products of Xian-Ling-Gu-Bao, a Traditional Chinese Medicine Prescription, with Rat Intestinal Microflora by Ultra-Performance Liquid Chromatography Tandem Triple Quadrupole Mass Spectrometry

Journal of chromatographic science, 2020-06, Vol.58 (6), p.494-503

2020

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PD-L1 expression and immune cells infiltration in primary tracheobronchial neoplasm

Translational lung cancer research, 2021-12, Vol.10 (12), p.4617-4630

2021

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Laparoscopic finding of a hepatic subcapsular spider-like telangiectasis sign in biliary atresia

World journal of gastroenterology : WJG, 2017-10, Vol.23 (39), p.7119-7128

2017

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Immune Checkpoint LAG3 and Its Ligand FGL1 in Cancer

Pharmacokinetics, hepatic disposition, and heart tissue distribution of 14 compounds in rat after oral administration of Qi‐Li‐Qiang‐Xin capsule via ultra‐high‐performance liquid chromatography coupled with triple quadrupole tandem mass spectrometry

An integrated strategy by absorbed component characterization, pharmacokinetics, and activity evaluation for identification of potential nephroprotective substances in Zhu‐Ling decoction

The Proliferative Role of Immune Checkpoints in Tumors: Double Regulation

Chemical and metabolic profiling of Codonopsis Radix extract with an integrated strategy using ultra‐high‐performance liquid chromatography coupled with mass spectrometry

Clinical Research on the Mechanisms Underlying Immune Checkpoints and Tumor Metastasis

Dual immunological and proliferative regulation of immune checkpoint FGL1 in lung adenocarcinoma: The pivotal role of the YY1–FGL1–MYH9 axis

An integrated strategy by chemical characterization, in vivo metabolism, chemical isolation, and activity evaluation to target discovery of potential active substances in traditional Chinese medicine: Mori Fructus as an example

Characterization of chemical components of Periplocae Cortex and their metabolites in rats using ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry

IGSF11 and VISTA: a pair of promising immune checkpoints in tumor immunotherapy

Biotransformation and metabolic profile of Xian‐Ling‐Gu‐Bao capsule, a traditional Chinese medicine prescription, with rat intestinal microflora by ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight tandem mass spectrometry analysis

A novel strategy with in vivo characterization, extraction, isolation and activity evaluation for discovery of absorbed anti-inflammatory oligosaccharides from Zhu-Ling decoction

A new strategy for discovering effective substances and mechanisms of traditional Chinese medicine based on standardized drug containing plasma and the absorbed ingredients composition, a case study of Xian-Ling-Gu-Bao capsules

Effects of Xian-Ling-Gu-Bao capsule on the gut microbiota in ovariectomized rats: Metabolism and modulation

A combination of representative compounds, metabolism platform and diagnostic extraction strategy for characterization of metabolites of Shuang-Huang-Lian oral liquid in vivo by ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry

Sweroside promotes osteoblastic differentiation and mineralization via interaction of membrane estrogen receptor-α and GPR30 mediated p38 signalling pathway on MC3T3-E1 cells

Simultaneous determination of multiple components in rat plasma and pharmacokinetic studies at a pharmacodynamic dose of Xian-Ling-Gu-Bao capsule by UPLC-MS/MS

An UHPLC-MS/MS method for simultaneous determination of ten sex steroid hormones in ovariectomy-induced osteoporosis rat and its application in discovery of sex steroid hormones regulatory components of Xian-Ling-Gu-Bao capsule

Systematic screening and characterization of Qi-Li-Qiang-Xin capsule-related xenobiotics in rats by ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry

Identification and characterization of chemical constituents in Qi-Lin pills and their metabolites in rat bio-samples after oral administration using ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry

Simultaneous determination of multiple constituents of Qi-Lin pill by UPLC-MS/MS: Applications to pharmacokinetics and testicular tissue distribution in rats

The downregulation of fibrinogen-like protein 1 inhibits the proliferation of lung adenocarcinoma via regulating MYC-target genes

Simultaneous Quantitative Analysis of Multiple Biotransformation Products of Xian-Ling-Gu-Bao, a Traditional Chinese Medicine Prescription, with Rat Intestinal Microflora by Ultra-Performance Liquid Chromatography Tandem Triple Quadrupole Mass Spectrometry

PD-L1 expression and immune cells infiltration in primary tracheobronchial neoplasm

Laparoscopic finding of a hepatic subcapsular spider-like telangiectasis sign in biliary atresia

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