UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 92

Sortiert nach

Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition

Cancer research (Chicago, Ill.), 2006-08, Vol.66 (16), p.8109-8115

2006

Volltextzugriff (PDF)

Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441

Cancer research (Chicago, Ill.), 2006-05, Vol.66 (10), p.5354-5362

2006

Volltextzugriff (PDF)

AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity

Cancer research (Chicago, Ill.), 2010, Vol.70 (1), p.288-298

2010

Volltextzugriff (PDF)

Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth by AZD2281 and Cisplatin

Clinical cancer research, 2008-06, Vol.14 (12), p.3916-3925

2008

Volltextzugriff (PDF)

Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathways

Cell reports (Cambridge), 2023-02, Vol.42 (2), p.112019, Article 112019

2023

Volltextzugriff (PDF)

Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes

Genes & development, 2009-05, Vol.23 (10), p.1207-1220

2009

Volltextzugriff (PDF)

Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries

Bioorganic & medicinal chemistry letters, 2004-12, Vol.14 (24), p.6083-6087

2004

Volltextzugriff (PDF)

Poly(ADP-Ribose) Polymerase-1 Inhibitor Treatment Regresses Autochthonous Brca2/p53-Mutant Mammary Tumors In vivo and Delays Tumor Relapse in Combination with Carboplatin

Cancer research (Chicago, Ill.), 2009-05, Vol.69 (9), p.3850-3855

2009

Volltextzugriff (PDF)

Poly(ADP-Ribose) Polymerase-1 and DNA-Dependent Protein Kinase Have Equivalent Roles in Double Strand Break Repair Following Ionizing Radiation

International journal of radiation oncology, biology, physics, 2009-12, Vol.75 (5), p.1520-1527

2009

Volltextzugriff (PDF)

Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis

Nature genetics, 1997-12, Vol.17 (4), p.479-482

1997

Volltextzugriff (PDF)

BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of poly (ADP-ribose) polymerase: An issue of potency

Cancer biology & therapy, 2005-09, Vol.4 (9), p.934-936

2005

Volltextzugriff (PDF)

Efficient deletion of normal Brca2-deficient intestinal epithelium by poly(ADP-ribose) polymerase inhibition models potential prophylactic therapy

Cancer research (Chicago, Ill.), 2005-11, Vol.65 (22), p.10145-10148

2005

Volltextzugriff (PDF)

Synthesis, crystal structure determination, and biological properties of the DNA-dependent protein kinase (DNA-PK) inhibitor 3-cyano-6-hydrazonomethyl-5-(4-pyridyl)pyrid-[1 H]-2-one (OK-1035)

Bioorganic & medicinal chemistry letters, 2001-11, Vol.11 (21), p.2837-2841

2001

Volltextzugriff (PDF)

DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

Cell, 1995-09, Vol.82 (5), p.849-856

1995

Volltextzugriff (PDF)

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation

Cell, 1995-03, Vol.80 (5), p.813-823

1995

Volltextzugriff (PDF)

POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells

Molecular cell, 2022-12, Vol.82 (24), p.4664-4680.e9

2022

Volltextzugriff (PDF)

2,6-Disubstituted pyran-4-one and thiopyran-4-one inhibitors of DNA-Dependent protein kinase (DNA-PK)

Bioorganic & medicinal chemistry letters, 2003-09, Vol.13 (18), p.3083-3086

2003

Volltextzugriff (PDF)

p21WAF1 is component of a positive feedback loop that maintains the p53 transcriptional program

Cell cycle (Georgetown, Tex.), 2011-03, Vol.10 (6), p.932-950

2011

Volltextzugriff (PDF)

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

Nature cell biology, 2006-01, Vol.8 (1), p.37-45

2006

Volltextzugriff (PDF)

Quantitative, titratable and high-throughput reporter assays to measure DNA double strand break repair activity in cells

Nucleic acids research, 2024-02, Vol.52 (4), p.1736

2024

Volltextzugriff (PDF)

Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps

Molecular cell, 2021-11, Vol.81 (22), p.4692-4708.e9

2021

Volltextzugriff (PDF)

4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1

Journal of medicinal chemistry, 2008-10, Vol.51 (20), p.6581-6591

2008

Volltextzugriff (PDF)

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Nature, 2005-04, Vol.434 (7035), p.917-921

2005

Volltextzugriff (PDF)

Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

Cancer research (Chicago, Ill.), 2004-12, Vol.64 (24), p.9152-9159

2004

Volltextzugriff (PDF)

1 – 25 von 92

Suche als RSS-Feed

Aktive Filter

Nur zeigenMit Volltextzugriff

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(85)

Publikationsform

Sprache

Englisch
(92)
Japanisch
(23)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition

Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441

AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity

Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth by AZD2281 and Cisplatin

Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathways

Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes

Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries

Poly(ADP-Ribose) Polymerase-1 Inhibitor Treatment Regresses Autochthonous Brca2/p53-Mutant Mammary Tumors In vivo and Delays Tumor Relapse in Combination with Carboplatin

Poly(ADP-Ribose) Polymerase-1 and DNA-Dependent Protein Kinase Have Equivalent Roles in Double Strand Break Repair Following Ionizing Radiation

Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis

BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of poly (ADP-ribose) polymerase: An issue of potency

Efficient deletion of normal Brca2-deficient intestinal epithelium by poly(ADP-ribose) polymerase inhibition models potential prophylactic therapy

Synthesis, crystal structure determination, and biological properties of the DNA-dependent protein kinase (DNA-PK) inhibitor 3-cyano-6-hydrazonomethyl-5-(4-pyridyl)pyrid-[1 H]-2-one (OK-1035)

DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation

POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells

2,6-Disubstituted pyran-4-one and thiopyran-4-one inhibitors of DNA-Dependent protein kinase (DNA-PK)

p21WAF1 is component of a positive feedback loop that maintains the p53 transcriptional program

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

Quantitative, titratable and high-throughput reporter assays to measure DNA double strand break repair activity in cells

Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps

4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta

Aktive Filter

Suchergebnisse filtern