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Annexin-A1: Therapeutic Potential in Microvascular Disease

Frontiers in immunology, 2019-04, Vol.10, p.938-938

2019

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Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages

Frontiers in immunology, 2018-06, Vol.9, p.1419-1419

2018

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Inhibition of Bruton's TK regulates macrophage NF‐κB and NLRP3 inflammasome activation in metabolic inflammation

British journal of pharmacology, 2020-10, Vol.177 (19), p.4416-4432

2020

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A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages

ACS chemical biology, 2019-09, Vol.14 (9), p.2055-2064

2019

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RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance

Frontiers in immunology, 2020-09, Vol.11, p.2080

2020

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Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice

Frontiers in immunology, 2019-09, Vol.10, p.2129-2129

2019

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Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes

Frontiers in immunology, 2019-03, Vol.10, p.571-571

2019

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A Human CD68 Promoter-Driven Inducible Cre-Recombinase Mouse Line Allows Specific Targeting of Tissue Resident Macrophages

Frontiers in immunology, 2022-07, Vol.13, p.918636

2022

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X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure

Frontiers in immunology, 2020-10, Vol.11, p.581758-581758

2020

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Ly6Chi Monocytes Are Metabolically Reprogrammed in the Blood during Inflammatory Stimulation and Require Intact OxPhos for Chemotaxis and Monocyte to Macrophage Differentiation

Cells (Basel, Switzerland), 2024-05, Vol.13 (11), p.916

2024

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A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice

Frontiers in immunology, 2021-07, Vol.12, p.701275-701275

2021

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Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis

Journal of the American Heart Association, 2017-07, Vol.6 (7), p.n/a

2017

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Bruton's TK regulates myeloid cell recruitment during acute inflammation

British journal of pharmacology, 2022-06, Vol.179 (11), p.2754-2770

2022

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Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes

Diabetologia, 2018-02, Vol.61 (2), p.482-495

2018

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OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity

Diabetes (New York, N.Y.), 2024-01

2024

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IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD

Journal of the American Society of Nephrology, 2017-01, Vol.28 (1), p.94-105

2017

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Drug repurposing screen identifies novel anti-inflammatory activity of sunitinib in macrophages

European journal of pharmacology, 2024-04, Vol.969, p.176437-176437, Article 176437

2024

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Novel Synthetic, Host-defense Peptide Protects Against Organ Injury/Dysfunction in a Rat Model of Severe Hemorrhagic Shock

Annals of surgery, 2018-08, Vol.268 (2), p.348-356

2018

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Efferocytosis perpetuates substance accumulation inside macrophage populations

Proceedings of the Royal Society. B, Biological sciences, 2019-06, Vol.286 (1904), p.20190730-20190730

2019

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Single Cell Transcriptomics Reveals How Hyperlipidaemia Alters Monocyte/macrophage Differentiation At Sites Of Inflammation

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Ly6C[sup.hi] Monocytes Are Metabolically Reprogrammed in the Blood during Inflammatory Stimulation and Require Intact OxPhos for Chemotaxis and Monocyte to Macrophage Differentiation

Cells (Basel, Switzerland), 2024-06, Vol.13 (11)

2024

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Ly6C hi Monocytes Are Metabolically Reprogrammed in the Blood during Inflammatory Stimulation and Require Intact OxPhos for Chemotaxis and Monocyte to Macrophage Differentiation

Cells (Basel, Switzerland), 2024-05, Vol.13 (11)

2024

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Efferocytosis perpetuates substance accumulation inside macrophage populations

Proceedings of the Royal Society. B, Biological sciences, 2019-06, Vol.286 (1904), p.1-9

2019

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The role of Annexin-A1 in the pathophysiology of diabetes

Purvis, Gareth S D

2018

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Annexin-A1: Therapeutic Potential in Microvascular Disease

Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages

Inhibition of Bruton's TK regulates macrophage NF‐κB and NLRP3 inflammasome activation in metabolic inflammation

A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages

RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance

Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice

Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes

A Human CD68 Promoter-Driven Inducible Cre-Recombinase Mouse Line Allows Specific Targeting of Tissue Resident Macrophages

X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure

Ly6Chi Monocytes Are Metabolically Reprogrammed in the Blood during Inflammatory Stimulation and Require Intact OxPhos for Chemotaxis and Monocyte to Macrophage Differentiation

A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice

Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis

Bruton's TK regulates myeloid cell recruitment during acute inflammation

Impact of metabolic disorders on the structural, functional, and immunological integrity of the blood‐brain barrier: Therapeutic avenues

Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes

OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity

IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD

Drug repurposing screen identifies novel anti-inflammatory activity of sunitinib in macrophages

Novel Synthetic, Host-defense Peptide Protects Against Organ Injury/Dysfunction in a Rat Model of Severe Hemorrhagic Shock

Efferocytosis perpetuates substance accumulation inside macrophage populations

Single Cell Transcriptomics Reveals How Hyperlipidaemia Alters Monocyte/macrophage Differentiation At Sites Of Inflammation

Ly6C[sup.hi] Monocytes Are Metabolically Reprogrammed in the Blood during Inflammatory Stimulation and Require Intact OxPhos for Chemotaxis and Monocyte to Macrophage Differentiation

Ly6C hi Monocytes Are Metabolically Reprogrammed in the Blood during Inflammatory Stimulation and Require Intact OxPhos for Chemotaxis and Monocyte to Macrophage Differentiation

Efferocytosis perpetuates substance accumulation inside macrophage populations

The role of Annexin-A1 in the pathophysiology of diabetes

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