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Clinical Pharmacokinetics and Pharmacodynamics of Bosutinib

Clinical pharmacokinetics, 2016-10, Vol.55 (10), p.1191-1204

2016

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Neoadjuvant PF-05280014 (a potential trastuzumab biosimilar) versus trastuzumab for operable HER2+ breast cancer

British journal of cancer, 2018-08, Vol.119 (3), p.266-273

2018

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Neratinib, an Irreversible ErbB Receptor Tyrosine Kinase Inhibitor, in Patients With Advanced ErbB2-Positive Breast Cancer

Journal of clinical oncology, 2010-03, Vol.28 (8), p.1301-1307

2010

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Phase I Study of Neratinib in Combination With Temsirolimus in Patients With Human Epidermal Growth Factor Receptor 2–Dependent and Other Solid Tumors

Journal of clinical oncology, 2014-01, Vol.32 (2), p.68-75

2014

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Application of Physiologically Based Pharmacokinetic Modeling to the Understanding of Bosutinib Pharmacokinetics: Prediction of Drug-Drug and Drug-Disease Interactions

Drug metabolism and disposition, 2017-04, Vol.45 (4), p.390-398

2017

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A Phase I Study with Neratinib (HKI-272), an Irreversible Pan ErbB Receptor Tyrosine Kinase Inhibitor, in Patients with Solid Tumors

Clinical cancer research, 2009-04, Vol.15 (7), p.2552-2558

2009

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A randomized, crossover, placebo- and moxifloxacin-controlled study to evaluate the effects of bosutinib (SKI-606), a dual Src/Abl tyrosine kinase inhibitor, on cardiac repolarization in healthy adult subjects

International journal of cancer, 2012-08, Vol.131 (3), p.E304-E311

2012

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Relative Bioavailability of Methylphenidate Extended-release Chewable Tablets Chewed Versus Swallowed Whole

Clinical therapeutics, 2018-05, Vol.40 (5), p.733-740

2018

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A phase I ascending single-dose study of the safety, tolerability, and pharmacokinetics of bosutinib (SKI-606) in healthy adult subjects

Cancer chemotherapy and pharmacology, 2012-01, Vol.69 (1), p.221-227

2012

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Pharmacokinetics of Novel Plant Cell-Expressed Taliglucerase Alfa in Adult and Pediatric Patients with Gaucher Disease

PloS one, 2015-06, Vol.10 (6), p.e0128986

2015

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Population Pharmacokinetic and Pharmacodynamic Analysis of Bosutinib

DRUG METABOLISM AND PHARMACOKINETICS, 2014, Vol.29 (6), p.441-448

2014

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Lack of an Effect of Supratherapeutic Dose of Venlafaxine on Cardiac Repolarization in Healthy Subjects

Clinical pharmacology in drug development, 2022-01, Vol.11 (1), p.100-111

2022

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Effect of Ketoconazole on the Pharmacokinetics of Oral Bosutinib in Healthy Subjects

Journal of clinical pharmacology, 2011-12, Vol.51 (12), p.1721-1727

2011

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Population Pharmacokinetics of Desvenlafaxine: Pharmacokinetics in Korean Versus US Populations

Clinical pharmacology in drug development, 2018-05, Vol.7 (4), p.441-450

2018

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Retraction notice to “Population pharmacokinetic and pharmacodynamic analysis of bosutinib” [Drug Metab Pharmacokinet 29 (2014) 441–448]

Drug metabolism and pharmacokinetics, 2019-04, Vol.34 (2), p.163-163

2019

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A Thorough QT Study to Evaluate the Effects of a Supratherapeutic Dose of Sertraline on Cardiac Repolarization in Healthy Subjects

Clinical pharmacology in drug development, 2020-04, Vol.9 (3), p.307-320

2020

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Single-Dose Pharmacokinetic Properties and Relative Bioavailability of a Novel Methylphenidate Extended-Release Chewable Tablet Compared With Immediate-Release Methylphenidate Chewable Tablet

Clinical therapeutics, 2016-05, Vol.38 (5), p.1151-1157

2016

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4.7 EFFICACY OF METHYLPHENIDATE EXTENDED-RELEASE CHEWABLE TABLETS IN CHILDREN WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER: OPEN-LABEL, DOSE-OPTIMIZATION PERIOD OUTCOMES

Journal of the American Academy of Child and Adolescent Psychiatry, 2016-10, Vol.55 (10), p.S164-S165

2016

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Ascending Single-Dose Study of the Safety Profile, Tolerability, and Pharmacokinetics of Bosutinib Coadministered With Ketoconazole to Healthy Adult Subjects

Clinical therapeutics, 2012-09, Vol.34 (9), p.2011-2019.e1

2012

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A Phase I Study of EKB-569 in Combination with Capecitabine in Patients with Advanced Colorectal Cancer

Clinical cancer research, 2008-09, Vol.14 (17), p.5602-5609

2008

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Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome–positive chronic myeloid leukemia patients with resistance or intolerance to imatinib

Blood, 2011-10, Vol.118 (17), p.4567-4576

2011

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Diagnosis and Treatment Options for Preschoolers with Attention-Deficit/Hyperactivity Disorder

Journal of child and adolescent psychopharmacology, 2020-03, Vol.30 (2), p.104-118

2020

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Effect of rifampin on the pharmacokinetics of bosutinib, a dual Src/Abl tyrosine kinase inhibitor, when administered concomitantly to healthy subjects

Drug metabolism and personalized therapy, 2015-03, Vol.30 (1), p.57-63

2015

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Considerations in the early development of biosimilar products

Drug discovery today, 2015-05, Vol.20, p.1-9

2015

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Clinical Pharmacokinetics and Pharmacodynamics of Bosutinib

Neoadjuvant PF-05280014 (a potential trastuzumab biosimilar) versus trastuzumab for operable HER2+ breast cancer

Neratinib, an Irreversible ErbB Receptor Tyrosine Kinase Inhibitor, in Patients With Advanced ErbB2-Positive Breast Cancer

Phase I Study of Neratinib in Combination With Temsirolimus in Patients With Human Epidermal Growth Factor Receptor 2–Dependent and Other Solid Tumors

Application of Physiologically Based Pharmacokinetic Modeling to the Understanding of Bosutinib Pharmacokinetics: Prediction of Drug-Drug and Drug-Disease Interactions

A Phase I Study with Neratinib (HKI-272), an Irreversible Pan ErbB Receptor Tyrosine Kinase Inhibitor, in Patients with Solid Tumors

A randomized, crossover, placebo- and moxifloxacin-controlled study to evaluate the effects of bosutinib (SKI-606), a dual Src/Abl tyrosine kinase inhibitor, on cardiac repolarization in healthy adult subjects

Relative Bioavailability of Methylphenidate Extended-release Chewable Tablets Chewed Versus Swallowed Whole

A phase I ascending single-dose study of the safety, tolerability, and pharmacokinetics of bosutinib (SKI-606) in healthy adult subjects

Pharmacokinetics of Novel Plant Cell-Expressed Taliglucerase Alfa in Adult and Pediatric Patients with Gaucher Disease

Population Pharmacokinetic and Pharmacodynamic Analysis of Bosutinib

Lack of an Effect of Supratherapeutic Dose of Venlafaxine on Cardiac Repolarization in Healthy Subjects

Effect of Ketoconazole on the Pharmacokinetics of Oral Bosutinib in Healthy Subjects

Population Pharmacokinetics of Desvenlafaxine: Pharmacokinetics in Korean Versus US Populations

Retraction notice to “Population pharmacokinetic and pharmacodynamic analysis of bosutinib” [Drug Metab Pharmacokinet 29 (2014) 441–448]

A Thorough QT Study to Evaluate the Effects of a Supratherapeutic Dose of Sertraline on Cardiac Repolarization in Healthy Subjects

Single-Dose Pharmacokinetic Properties and Relative Bioavailability of a Novel Methylphenidate Extended-Release Chewable Tablet Compared With Immediate-Release Methylphenidate Chewable Tablet

4.7 EFFICACY OF METHYLPHENIDATE EXTENDED-RELEASE CHEWABLE TABLETS IN CHILDREN WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER: OPEN-LABEL, DOSE-OPTIMIZATION PERIOD OUTCOMES

Ascending Single-Dose Study of the Safety Profile, Tolerability, and Pharmacokinetics of Bosutinib Coadministered With Ketoconazole to Healthy Adult Subjects

A Phase I Study of EKB-569 in Combination with Capecitabine in Patients with Advanced Colorectal Cancer

Phase I Pharmacokinetic/Pharmacodynamic Study of EKB-569, an Irreversible Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase, in Combination with Irinotecan, 5-Fluorouracil, and Leucovorin (FOLFIRI) in First-Line Treatment of Patients with Metastatic Colorectal Cancer

Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome–positive chronic myeloid leukemia patients with resistance or intolerance to imatinib

Diagnosis and Treatment Options for Preschoolers with Attention-Deficit/Hyperactivity Disorder

Effect of rifampin on the pharmacokinetics of bosutinib, a dual Src/Abl tyrosine kinase inhibitor, when administered concomitantly to healthy subjects

Considerations in the early development of biosimilar products

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