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Synthesis and structure–activity relationship of a novel sulfone series of TNF-α converting enzyme inhibitors

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (17), p.4453-4459

2004

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Design, Synthesis, and Structure−Activity Relationships of Macrocyclic Hydroxamic Acids That Inhibit Tumor Necrosis Factor α Release in Vitro and in Vivo

Journal of medicinal chemistry, 2001-08, Vol.44 (16), p.2636-2660

2001

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Novel 1-(pyridylphenyl)-1-phenyl-2-imidazolylethanols with topical antiinflammatory activity

Journal of medicinal chemistry, 1992-08, Vol.35 (17), p.3148-3155

1992

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Characterization of the 31P nuclear magnetic resonance spectrum from human melanoma tumors implanted in nude mice

Cancer research (Chicago, Ill.), 1987-10, Vol.47 (19), p.5065-5069

1987

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Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis

Journal of hepatology, 2013-04, Vol.58 (4), p.778-784

2013

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P2X7 receptor-NADPH oxidase axis mediates protein radical formation and Kupffer cell activation in carbon tetrachloride-mediated steatohepatitis in obese mice

Free radical biology & medicine, 2012-05, Vol.52 (9), p.1666-1679

2012

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In vivo lipid‐derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide: a model for ARDS

The FASEB journal, 2002-11, Vol.16 (13), p.1713-1720

2002

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Synergistic Production of Lung Free Radicals by Diesel Exhaust Particles and Endotoxin

American journal of respiratory and critical care medicine, 2005-02, Vol.171 (4), p.379-387

2005

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In vivo evidence of free radical generation in the mouse lung after exposure to Pseudomonas aeruginosa bacterium: An ESR spin-trapping investigation

Free radical research, 2012-05, Vol.46 (5), p.645-655

2012

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Oxidative stress induces protein and DNA radical formation in follicular dendritic cells of the germinal center and modulates its cell death patterns in late sepsis

Free radical biology & medicine, 2011-04, Vol.50 (8), p.988-999

2011

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Constitutive nitric oxide synthase activation is a significant route for nitroglycerin-mediated vasodilation

Proceedings of the National Academy of Sciences - PNAS, 2008-06, Vol.105 (25), p.8569-8574

2008

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Site-Specific Carboxypeptidase B1 Tyrosine Nitration and Pathophysiological Implications following Its Physical Association with Nitric Oxide Synthase-3 in Experimental Sepsis

The Journal of immunology (1950), 2009-09, Vol.183 (6), p.4055-4066

2009

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Immuno-spin trapping of a post-translational carboxypeptidase B1 radical formed by a dual role of xanthine oxidase and endothelial nitric oxide synthase in acute septic mice

Free radical biology & medicine, 2009-02, Vol.46 (4), p.454-461

2009

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Synthesis and Antitumor Activity of 4-Aminomethylthioxanthenone and 5-Aminomethylbenzothiopyranoindazole Derivatives

Journal of medicinal chemistry, 1998-09, Vol.41 (19), p.3645-3654

1998

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Mechanism of action and antitumor activity of ( S)-10-(2,6-dimethyl-4-pyridinyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7 H-pyridol [1,2,3- de]-[1,4]benzothiazine-6-carboxylic acid (WIN 58161)

Biochemical pharmacology, 1995-06, Vol.50 (1), p.111-122

1995

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Synthesis and structure–activity relationship of a novel sulfone series of TNF-α converting enzyme inhibitors

Design, Synthesis, and Structure−Activity Relationships of Macrocyclic Hydroxamic Acids That Inhibit Tumor Necrosis Factor α Release in Vitro and in Vivo

Novel 1-(pyridylphenyl)-1-phenyl-2-imidazolylethanols with topical antiinflammatory activity

Characterization of the 31P nuclear magnetic resonance spectrum from human melanoma tumors implanted in nude mice

Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis

P2X7 receptor-NADPH oxidase axis mediates protein radical formation and Kupffer cell activation in carbon tetrachloride-mediated steatohepatitis in obese mice

In vivo lipid‐derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide: a model for ARDS

Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody-Drug Conjugate Targeting PSMA, in Preclinical Models of Prostate Cancer

Synergistic Production of Lung Free Radicals by Diesel Exhaust Particles and Endotoxin

In vivo evidence of free radical generation in the mouse lung after exposure to Pseudomonas aeruginosa bacterium: An ESR spin-trapping investigation

Oxidative stress induces protein and DNA radical formation in follicular dendritic cells of the germinal center and modulates its cell death patterns in late sepsis

Constitutive nitric oxide synthase activation is a significant route for nitroglycerin-mediated vasodilation

Site-Specific Carboxypeptidase B1 Tyrosine Nitration and Pathophysiological Implications following Its Physical Association with Nitric Oxide Synthase-3 in Experimental Sepsis

Immuno-spin trapping of a post-translational carboxypeptidase B1 radical formed by a dual role of xanthine oxidase and endothelial nitric oxide synthase in acute septic mice

Synthesis and Antitumor Activity of 4-Aminomethylthioxanthenone and 5-Aminomethylbenzothiopyranoindazole Derivatives

Mechanism of action and antitumor activity of ( S)-10-(2,6-dimethyl-4-pyridinyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7 H-pyridol [1,2,3- de]-[1,4]benzothiazine-6-carboxylic acid (WIN 58161)

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