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2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6275), p.871-875

2016

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Stairway to translocation: AAA+ motor structures reveal the mechanisms of ATP‐dependent substrate translocation

Protein science, 2020-02, Vol.29 (2), p.407-419

2020

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Structural mechanism of cytosolic DNA sensing by cGAS

Nature (London), 2013-06, Vol.498 (7454), p.332-337

2013

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Agonist-bound structure of the human P2Y12 receptor

Nature (London), 2014-05, Vol.509 (7498), p.119-122

2014

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Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

Science (American Association for the Advancement of Science), 2019-02, Vol.363 (6428), p.753-756

2019

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A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP

Nature communications, 2019-02, Vol.10 (1), p.711-13, Article 711

2019

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Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

Nature communications, 2019-03, Vol.10 (1), p.1155-1155, Article 1155

2019

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Dynamic Chemistry of DNA-Based Nanoassemblies in Living Cells

Accounts of chemical research, 2024-10, Vol.57 (19), p.2763-2774

2024

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Cryo-EM structures capture the transport cycle of the P4-ATPase flippase

Science (American Association for the Advancement of Science), 2019-09, Vol.365 (6458), p.1149-1155

2019

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Real-Time Electrochemical Monitoring of Adenosine Triphosphate in the Picomolar to Micromolar Range Using Graphene-Modified Electrodes

Analytical chemistry (Washington), 2013-09, Vol.85 (17), p.8158-8165

2013

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Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome

Nature communications, 2018-04, Vol.9 (1), p.1360-12, Article 1360

2018

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Mechanistic diversity in ATP-binding cassette (ABC) transporters

Nature structural & molecular biology, 2016-06, Vol.23 (6), p.487-493

Locher, Kaspar P

2016

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Structure of human argininosuccinate synthetase

Acta crystallographica. Section D, Biological crystallography., 2008-03, Vol.64 (3), p.279-286

2008

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Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

Science (American Association for the Advancement of Science), 2018-02, Vol.359 (6378), p.915-919

2018

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The Hsp70–Hsp90 Chaperone Cascade in Protein Folding

Trends in cell biology, 2019-02, Vol.29 (2), p.164-177

2019

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A review of methods for the detection of pathogenic microorganisms

Analyst (London), 2019-01, Vol.144 (2), p.396-411

2019

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Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors

Science (American Association for the Advancement of Science), 2019-05, Vol.364 (6441), p.689-692

2019

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mTOR kinase structure, mechanism and regulation

Nature (London), 2013-05, Vol.497 (7448), p.217-223

2013

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Cryo-EM structures of the ATP release channel pannexin 1

Nature structural & molecular biology, 2020-04, Vol.27 (4), p.373-381

2020

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Cationic Europium Complexes for Visualizing Fluctuations in Mitochondrial ATP Levels in Living Cells

Chemistry : a European journal, 2018-07, Vol.24 (42), p.10745-10755

2018

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CryoEM structures of human CMG-ATPγS-DNA and CMG-AND-1 complexes

Nucleic acids research, 2020-07, Vol.48 (12), p.6980-6995

2020

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Discovery of COVID-19 Inhibitors Targeting the SARS-CoV‑2 Nsp13 Helicase

The journal of physical chemistry letters, 2020-11, Vol.11 (21), p.9144-9151

2020

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Electrochemical Nanoaptasensor for Continuous Monitoring of ATP Fluctuation at Subcellular Level

Analytical chemistry (Washington), 2020-08, Vol.92 (16), p.10940-10945

2020

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Nitrogen and phosphorus co-doped graphene quantum dots: synthesis from adenosine triphosphate, optical properties, and cellular imaging

Nanoscale, 2015-05, Vol.7 (17), p.8159-8165

2015

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Structural basis for power stroke vs. Brownian ratchet mechanisms of motor proteins

Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (40), p.19777-19785

2019

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2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

Stairway to translocation: AAA+ motor structures reveal the mechanisms of ATP‐dependent substrate translocation

Structural mechanism of cytosolic DNA sensing by cGAS

Agonist-bound structure of the human P2Y12 receptor

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

Dynamic Chemistry of DNA-Based Nanoassemblies in Living Cells

Cryo-EM structures capture the transport cycle of the P4-ATPase flippase

Real-Time Electrochemical Monitoring of Adenosine Triphosphate in the Picomolar to Micromolar Range Using Graphene-Modified Electrodes

Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome

Mechanistic diversity in ATP-binding cassette (ABC) transporters

Structure of human argininosuccinate synthetase

Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

The Hsp70–Hsp90 Chaperone Cascade in Protein Folding

A review of methods for the detection of pathogenic microorganisms

Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors

mTOR kinase structure, mechanism and regulation

Cryo-EM structures of the ATP release channel pannexin 1

Cationic Europium Complexes for Visualizing Fluctuations in Mitochondrial ATP Levels in Living Cells

CryoEM structures of human CMG-ATPγS-DNA and CMG-AND-1 complexes

Discovery of COVID-19 Inhibitors Targeting the SARS-CoV‑2 Nsp13 Helicase

Electrochemical Nanoaptasensor for Continuous Monitoring of ATP Fluctuation at Subcellular Level

Nitrogen and phosphorus co-doped graphene quantum dots: synthesis from adenosine triphosphate, optical properties, and cellular imaging

Structural basis for power stroke vs. Brownian ratchet mechanisms of motor proteins

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