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PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II

Cell, 2015-08, Vol.162 (5), p.1003-1015

2015

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The Chromatin Signaling Pathway: Diverse Mechanisms of Recruitment of Histone-Modifying Enzymes and Varied Biological Outcomes

Molecular cell, 2010-12, Vol.40 (5), p.689-701

2010

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Zic2 Is an Enhancer-Binding Factor Required for Embryonic Stem Cell Specification

Molecular cell, 2015-02, Vol.57 (4), p.685-694

2015

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The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers

Molecular and Cellular Biology, 2013-12, Vol.33 (23), p.4745-4754

2013

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AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

Molecular cell, 2010-02, Vol.37 (3), p.429-437

2010

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Covalent modifications of histones during development and disease pathogenesis

Nature Structural & Molecular Biology, 2007-11, Vol.14 (11), p.1008-1016

2007

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Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors

Cell, 2011-07, Vol.146 (1), p.92-104

2011

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Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy

Cell, 2018-10, Vol.175 (3), p.766-779.e17

2018

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Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy

Nature medicine, 2018-06, Vol.24 (6), p.758-769

2018

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NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release

Molecular cell, 2020-04, Vol.78 (2), p.261-274.e5

2020

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The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells

Nature structural & molecular biology, 2013-09, Vol.20 (9), p.1093-1097

2013

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Characterization of Human Cyclin-Dependent Kinase 12 (CDK12) and CDK13 Complexes in C-Terminal Domain Phosphorylation, Gene Transcription, and RNA Processing

Molecular and cellular biology, 2015-03, Vol.35 (6), p.928-938

2015

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The Little Elongation Complex Functions at Initiation and Elongation Phases of snRNA Gene Transcription

Molecular cell, 2013-08, Vol.51 (4), p.493-505

2013

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The Little Elongation Complex Regulates Small Nuclear RNA Transcription

Molecular cell, 2011-12, Vol.44 (6), p.954-965

2011

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Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II

Molecular and Cellular Biology, 2009-11, Vol.29 (22), p.6074-6085

2009

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The COMPASS Family of H3K4 Methylases in Drosophila

Molecular and Cellular Biology, 2011-11, Vol.31 (21), p.4310-4318

2011

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Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia

Cell, 2017-01, Vol.168 (1-2), p.59-72.e13

2017

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Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification

Molecular cell, 2017-02, Vol.65 (3), p.460-475.e6

2017

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Enhancer biology and enhanceropathies

Nature structural & molecular biology, 2014-03, Vol.21 (3), p.210-219

2014

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A Human Protein Complex Homologous to the Drosophila MSL Complex Is Responsible for the Majority of Histone H4 Acetylation at Lysine 16

Molecular and Cellular Biology, 2005-11, Vol.25 (21), p.9175-9188

2005

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A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cells

Genome research, 2021-09, Vol.31 (9), p.1663-1679

2021

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Drosophila UTX Is a Histone H3 Lys27 Demethylase That Colocalizes with the Elongating Form of RNA Polymerase II

Molecular and Cellular Biology, 2008-02, Vol.28 (3), p.1041-1046

2008

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Analysis of dynamic changes in retinoid-induced transcription and epigenetic profiles of murine Hox clusters in ES cells

Genome research, 2015-08, Vol.25 (8), p.1229-1243

2015

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Involvement of Human MOF in ATM Function

Molecular and Cellular Biology, 2005-06, Vol.25 (12), p.5292-5305

2005

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The MLE Subunit of the Drosophila MSL Complex Uses Its ATPase Activity for Dosage Compensation and Its Helicase Activity for Targeting

Molecular and Cellular Biology, 2008-02, Vol.28 (3), p.958-966

2008

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PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II

The Chromatin Signaling Pathway: Diverse Mechanisms of Recruitment of Histone-Modifying Enzymes and Varied Biological Outcomes

Zic2 Is an Enhancer-Binding Factor Required for Embryonic Stem Cell Specification

The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers

AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

Covalent modifications of histones during development and disease pathogenesis

Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors

Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy

NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release

The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells

Characterization of Human Cyclin-Dependent Kinase 12 (CDK12) and CDK13 Complexes in C-Terminal Domain Phosphorylation, Gene Transcription, and RNA Processing

The Little Elongation Complex Functions at Initiation and Elongation Phases of snRNA Gene Transcription

The Little Elongation Complex Regulates Small Nuclear RNA Transcription

Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II

The COMPASS Family of H3K4 Methylases in Drosophila

Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia

Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification

Enhancer biology and enhanceropathies

A Human Protein Complex Homologous to the Drosophila MSL Complex Is Responsible for the Majority of Histone H4 Acetylation at Lysine 16

A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cells

Drosophila UTX Is a Histone H3 Lys27 Demethylase That Colocalizes with the Elongating Form of RNA Polymerase II

Analysis of dynamic changes in retinoid-induced transcription and epigenetic profiles of murine Hox clusters in ES cells

Involvement of Human MOF in ATM Function

The MLE Subunit of the Drosophila MSL Complex Uses Its ATPase Activity for Dosage Compensation and Its Helicase Activity for Targeting

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