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Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice

Neuropharmacology, 2013-02, Vol.65, p.29-38

2013

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Age-related pharmacokinetic changes of acetaminophen, antipyrine, diazepam, diphenhydramine, and ofloxacin in male cynomolgus monkeys and beagle dogs

Xenobiotica, 2014-10, Vol.44 (10), p.893-901

2014

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Assessment of absorption potential of poorly water-soluble drugs by using the dissolution/permeation system

European journal of pharmaceutics and biopharmaceutics, 2013-11, Vol.85 (3), p.1317-1324

2013

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The Selective Metabotropic Glutamate 2/3 Receptor Agonist MGS0028 Reverses Isolation Rearing–Induced Abnormal Behaviors in Mice

Journal of Pharmacological Sciences, 2012, Vol.118(2), pp.295-298

2012

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Consumption of wild boar linked to cases of hepatitis E

Journal of hepatology, 2004-05, Vol.40 (5), p.869-870

2004

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QT PRODACT: In Vivo QT Assay in the Conscious Dog for Assessing the Potential for QT Interval Prolongation by Human Pharmaceuticals

Journal of Pharmacological Sciences, 2005, Vol.99(5), pp.459-471

2005

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Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice

Neuropharmacology, 2011-02, Vol.60 (2-3), p.397-404

2011

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Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission

Psychopharmacologia, 2011-10, Vol.217 (3), p.443-452

2011

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Amlexanox enhances the antitumor effect of anti-PD-1 antibody

Biochemical and biophysical research communications, 2021-06, Vol.560, p.1-6

2021

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Role of prefrontal dopaminergic neurotransmission in glucocorticoid receptor-mediated modulation of methamphetamine-induced hyperactivity

Synapse (New York, N.Y.), 2009-01, Vol.63 (1), p.7-14

2009

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Possibility of Undeveloped Egg Absorption during Embryogenesis: A Unique Phenomenon Observed in the Ovoviviparous Mayfly Cloeon dipterum

Zoological science, 2021-02, Vol.38 (1), p.20

2021

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Pharmacokinetic-Pharmacodynamic Modeling of Brain Dopamine Levels Based on Dopamine Transporter Occupancy after Administration of Methylphenidate in Rats

The Journal of pharmacology and experimental therapeutics, 2019-04, Vol.369 (1), p.78-87

2019

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In vivo hepatic clearance of lipophilic drugs predicted by in vitro uptake data into cryopreserved hepatocytes suspended in sera of rats, guinea pigs, monkeys and humans

Xenobiotica, 2019-08, Vol.49 (8), p.887-894

2019

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Fluvoxamine enhances prefrontal dopaminergic neurotransmission in adrenalectomized/castrated mice via both 5-HT reuptake inhibition and σ(1) receptor activation

Psychopharmacology (Berlin, Germany), 2011-10, Vol.217 (3), p.377-386

2011

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Antidepressant-like effects of the glucocorticoid receptor antagonist RU-43044 are associated with changes in prefrontal dopamine in mouse models of depression

Neuropharmacology, 2008-12, Vol.55 (8), p.1355-1363

2008

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Avanafil, a Highly Selective Phosphodiesterase Type 5 Inhibitor for Erectile Dysfunction, Shows Good Safety Profiles for Retinal Function and Hemodynamics in Anesthetized Dogs

The Journal of urology, 2013-08, Vol.190 (2), p.799-806

2013

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Age-related changes of hepatic clearances of cytochrome P450 probes, midazolam and R-/S-warfarin in combination with caffeine, omeprazole and metoprolol in cynomolgus monkeys using in vitro-in vivo correlation

Xenobiotica, 2015-04, Vol.45 (4), p.312-321

2015

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Acute and Chronic Effects of T-1032, a Novel Selective Phosphodiesterase Type 5 Inhibitor, on Monocrotaline-Induced Pulmonary Hypertension in Rats

Biological and Pharmaceutical Bulletin, 2002, Vol.25(11), pp.1422-1426

2002

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Genealogical Position of Japanese Populations of the Globally Distributed Mayfly Cloeon dipterum and Related Species (Ephemeroptera, Baetidae): A Molecular Phylogeographic Analysis

Zoological science, 2019-12, Vol.36 (6), p.479

2019

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IgE enhances Fc epsilon receptor I expression and IgE-dependent release of histamine and lipid mediators from human umbilical cord blood-derived mast cells: synergistic effect of IL-4 and IgE on human mast cell Fc epsilon receptor I expression and mediator release

The Journal of immunology (1950), 1999-05, Vol.162 (9), p.5455-5465

1999

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Discovery of new orally active prostaglandin D2 receptor antagonists

Bioorganic & medicinal chemistry, 2011-11, Vol.19 (22), p.6935-6948

2011

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Sildenafil and T-1032, phosphodiesterase type 5 inhibitors, showed a different vasorelaxant property in the isolated rat aorta

European journal of pharmacology, 2002-04, Vol.440 (1), p.45-52

2002

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T-0156, a novel phosphodiesterase type 5 inhibitor, and sildenafil have different pharmacological effects on penile tumescence and electroretinogram in dogs

European journal of pharmacology, 2004-02, Vol.485 (1), p.283-288

2004

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Calcium-Induced Weakening of Z-Disks in Postmortem Skeletal Muscle

Journal of biochemistry (Tokyo), 1987-03, Vol.101 (3), p.767-773

1987

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Pharmacological profile of T-1032, a novel specific phosphodiesterase type 5 inhibitor, in isolated rat aorta and rabbit corpus cavernosum

European journal of pharmacology, 2001-01, Vol.411 (1-2), p.161-168

2001

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Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice

Age-related pharmacokinetic changes of acetaminophen, antipyrine, diazepam, diphenhydramine, and ofloxacin in male cynomolgus monkeys and beagle dogs

Assessment of absorption potential of poorly water-soluble drugs by using the dissolution/permeation system

The Selective Metabotropic Glutamate 2/3 Receptor Agonist MGS0028 Reverses Isolation Rearing–Induced Abnormal Behaviors in Mice

Consumption of wild boar linked to cases of hepatitis E

QT PRODACT: In Vivo QT Assay in the Conscious Dog for Assessing the Potential for QT Interval Prolongation by Human Pharmaceuticals

Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice

Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission

Amlexanox enhances the antitumor effect of anti-PD-1 antibody

Role of prefrontal dopaminergic neurotransmission in glucocorticoid receptor-mediated modulation of methamphetamine-induced hyperactivity

Possibility of Undeveloped Egg Absorption during Embryogenesis: A Unique Phenomenon Observed in the Ovoviviparous Mayfly Cloeon dipterum

Pharmacokinetic-Pharmacodynamic Modeling of Brain Dopamine Levels Based on Dopamine Transporter Occupancy after Administration of Methylphenidate in Rats

In vivo hepatic clearance of lipophilic drugs predicted by in vitro uptake data into cryopreserved hepatocytes suspended in sera of rats, guinea pigs, monkeys and humans

Fluvoxamine enhances prefrontal dopaminergic neurotransmission in adrenalectomized/castrated mice via both 5-HT reuptake inhibition and σ(1) receptor activation

Antidepressant-like effects of the glucocorticoid receptor antagonist RU-43044 are associated with changes in prefrontal dopamine in mouse models of depression

Avanafil, a Highly Selective Phosphodiesterase Type 5 Inhibitor for Erectile Dysfunction, Shows Good Safety Profiles for Retinal Function and Hemodynamics in Anesthetized Dogs

Age-related changes of hepatic clearances of cytochrome P450 probes, midazolam and R-/S-warfarin in combination with caffeine, omeprazole and metoprolol in cynomolgus monkeys using in vitro-in vivo correlation

Acute and Chronic Effects of T-1032, a Novel Selective Phosphodiesterase Type 5 Inhibitor, on Monocrotaline-Induced Pulmonary Hypertension in Rats

Genealogical Position of Japanese Populations of the Globally Distributed Mayfly Cloeon dipterum and Related Species (Ephemeroptera, Baetidae): A Molecular Phylogeographic Analysis

IgE enhances Fc epsilon receptor I expression and IgE-dependent release of histamine and lipid mediators from human umbilical cord blood-derived mast cells: synergistic effect of IL-4 and IgE on human mast cell Fc epsilon receptor I expression and mediator release

Discovery of new orally active prostaglandin D2 receptor antagonists

Sildenafil and T-1032, phosphodiesterase type 5 inhibitors, showed a different vasorelaxant property in the isolated rat aorta

T-0156, a novel phosphodiesterase type 5 inhibitor, and sildenafil have different pharmacological effects on penile tumescence and electroretinogram in dogs

Calcium-Induced Weakening of Z-Disks in Postmortem Skeletal Muscle

Pharmacological profile of T-1032, a novel specific phosphodiesterase type 5 inhibitor, in isolated rat aorta and rabbit corpus cavernosum

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