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Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L

Acta pharmacologica Sinica, 2018-05, Vol.39 (5), p.787-801

2018

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Isolation, Chemical, and Biotransformation Routes of Labdane-type Diterpenes

Chemical reviews, 2011-08, Vol.111 (8), p.4418-4452

2011

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An integrated strategy for revealing the pharmacological changes based on metabolites profiling and network pharmacology: Arctiin as an example

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020-11, Vol.1157, p.122270, Article 122270

2020

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Design, synthesis and biological evaluation of fused naphthofuro[3,2-c] quinoline-6,7,12-triones and pyrano[3,2-c]quinoline-6,7,8,13-tetraones derivatives as ERK inhibitors with efficacy in BRAF-mutant melanoma

Bioorganic chemistry, 2019-02, Vol.82, p.290-305

2019

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4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase

Bioorganic & medicinal chemistry letters, 2016-01, Vol.26 (2), p.534-539

2016

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Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with Anthracycline Impairs PI3K Signaling, Increases DNA Damage Response and Reduces Breast Cancer Cell Growth

International journal of molecular sciences, 2021-02, Vol.22 (4), p.2088

2021

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Effect of Soy Sauce on Serum Uric Acid Levels in Hyperuricemic Rats and Identification of Flazin as a Potent Xanthine Oxidase Inhibitor

Journal of agricultural and food chemistry, 2016-06, Vol.64 (23), p.4725-4734

2016

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Lead optimization of the VU0486321 series of mGlu(1) PAMs. Part 2: SAR of alternative 3-methyl heterocycles and progress towards an in vivo tool

Bioorganic & medicinal chemistry letters, 2016-02, Vol.26 (3), p.751-756

2016

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NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice-A Novel in Vivo Imaging Platform

International journal of molecular sciences, 2020-08, Vol.21 (16), p.5863

2020

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Detection of Maillard Reaction Product [5-(5,6-Dihydro‑4H‑pyridin-3-ylidenemethyl)furan-2-yl]methanol (F3-A) in Breads and Demonstration of Bioavailability in Caco‑2 Intestinal Cells

Journal of agricultural and food chemistry, 2016-11, Vol.64 (47), p.9072-9077

2016

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Comparative absorption kinetics of seven active ingredients of Eucommia ulmoides extracts by intestinal in situ circulatory perfusion in normal and spontaneous hypertensive rats

Biomedical chromatography, 2020-01, Vol.34 (1), p.e4714-n/a

2020

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Synthesis and SAR of 5-aryl-furan-2-carboxamide derivatives as potent urotensin-II receptor antagonists

Bioorganic & medicinal chemistry letters, 2019-02, Vol.29 (4), p.577-580

2019

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Validation and application of a novel UHPLC–MS/MS method for the measurement of furanodienone in rat plasma

Biomedical chromatography, 2020-01, Vol.34 (1), p.e4717-n/a

2020

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Method development for quantification of the environmental neurotoxin annonacin in Rat plasma by UPLC–MS/MS and application to a pharmacokinetic study

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015-11, Vol.1004, p.46-52

2015

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Design of Tenofovir–UC781 Combination Microbicide Vaginal Gels

Journal of pharmaceutical sciences, 2012-05, Vol.101 (5), p.1852-1864

2012

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UHPLC‐ESI‐MS/MS determination and pharmacokinetics of pinoresinol glucoside and chlorogenic acid in rat plasma after oral administration of Eucommia ulmoides Oliv extract

Biomedical chromatography, 2017-11, Vol.31 (11), p.n/a

2017

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Site-directed decapsulation of bolaamphiphilic vesicles with enzymatic cleavable surface groups

Journal of controlled release, 2012-06, Vol.160 (2), p.306-314

2012

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Determination of manassantin B in rat plasma using a high performance liquid chromatography with fluorescence detection and its quantitative application to pharmacokinetic study

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016-02, Vol.1011, p.121-127

2016

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Metabolism of a Serotonin-4 Receptor Partial Agonist 4-{4-[4-Tetrahydrofuran-3-yloxy)-Benzo[d]Isoxazol-3-yloxymethyl]-Piperidin-1-ylmethyl}-Tetrahydropyran-4-ol (TBPT): Identification of an Unusual Pharmacologically Active Cyclized Oxazolidine Metabolite in Human

Journal of pharmaceutical sciences, 2013-09, Vol.102 (9), p.3277-3293

2013

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In vitro metabolism study of the promising anticancer agent the lignan (−)-grandisin

Journal of pharmaceutical and biomedical analysis, 2013-01, Vol.72 (18), p.240-244

2013

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Study on pharmacokinetics of 3,4-divanillyltetrahydrofuran in rats by ultra-fast liquid chromatography/tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016-01, Vol.1008, p.250-254

2016

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N‑Acetyl Lysine/Glutathione-Derived Pyrroles as Potential Ex Vivo Biomarkers of Bioactivated Furan-Containing Compounds

Chemical research in toxicology, 2015-03, Vol.28 (3), p.384-393

2015

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Determination of Ginkgolides A, B, C, J and Bilobalide in Plasma by LC-ESI (-)/MS/MS (QQQ) and its Application to the Pharmacokinetic Study of Ginkgo Biloba Extract in Rats

Drug research, 2016-10, Vol.66 (10), p.520

2016

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Tissue Distribution and Cytochrome P450 Inhibition of Sesaminol and Its Tetrahydrofuranoid Metabolites

Journal of agricultural and food chemistry, 2012-09, Vol.60 (35), p.8616-8623

2012

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Discovery and optimization of novel purines as potent and selective CB2 agonists

Bioorganic & medicinal chemistry letters, 2012-08, Vol.22 (15), p.4962-4966

2012

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Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L

Isolation, Chemical, and Biotransformation Routes of Labdane-type Diterpenes

An integrated strategy for revealing the pharmacological changes based on metabolites profiling and network pharmacology: Arctiin as an example

Design, synthesis and biological evaluation of fused naphthofuro[3,2-c] quinoline-6,7,12-triones and pyrano[3,2-c]quinoline-6,7,8,13-tetraones derivatives as ERK inhibitors with efficacy in BRAF-mutant melanoma

4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase

Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with Anthracycline Impairs PI3K Signaling, Increases DNA Damage Response and Reduces Breast Cancer Cell Growth

Effect of Soy Sauce on Serum Uric Acid Levels in Hyperuricemic Rats and Identification of Flazin as a Potent Xanthine Oxidase Inhibitor

Lead optimization of the VU0486321 series of mGlu(1) PAMs. Part 2: SAR of alternative 3-methyl heterocycles and progress towards an in vivo tool

NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice-A Novel in Vivo Imaging Platform

Detection of Maillard Reaction Product [5-(5,6-Dihydro‑4H‑pyridin-3-ylidenemethyl)furan-2-yl]methanol (F3-A) in Breads and Demonstration of Bioavailability in Caco‑2 Intestinal Cells

Comparative absorption kinetics of seven active ingredients of Eucommia ulmoides extracts by intestinal in situ circulatory perfusion in normal and spontaneous hypertensive rats

Synthesis and SAR of 5-aryl-furan-2-carboxamide derivatives as potent urotensin-II receptor antagonists

Validation and application of a novel UHPLC–MS/MS method for the measurement of furanodienone in rat plasma

Method development for quantification of the environmental neurotoxin annonacin in Rat plasma by UPLC–MS/MS and application to a pharmacokinetic study

Design of Tenofovir–UC781 Combination Microbicide Vaginal Gels

UHPLC‐ESI‐MS/MS determination and pharmacokinetics of pinoresinol glucoside and chlorogenic acid in rat plasma after oral administration of Eucommia ulmoides Oliv extract

Site-directed decapsulation of bolaamphiphilic vesicles with enzymatic cleavable surface groups

Determination of manassantin B in rat plasma using a high performance liquid chromatography with fluorescence detection and its quantitative application to pharmacokinetic study

Metabolism of a Serotonin-4 Receptor Partial Agonist 4-{4-[4-Tetrahydrofuran-3-yloxy)-Benzo[d]Isoxazol-3-yloxymethyl]-Piperidin-1-ylmethyl}-Tetrahydropyran-4-ol (TBPT): Identification of an Unusual Pharmacologically Active Cyclized Oxazolidine Metabolite in Human

In vitro metabolism study of the promising anticancer agent the lignan (−)-grandisin

Study on pharmacokinetics of 3,4-divanillyltetrahydrofuran in rats by ultra-fast liquid chromatography/tandem mass spectrometry

N‑Acetyl Lysine/Glutathione-Derived Pyrroles as Potential Ex Vivo Biomarkers of Bioactivated Furan-Containing Compounds

Determination of Ginkgolides A, B, C, J and Bilobalide in Plasma by LC-ESI (-)/MS/MS (QQQ) and its Application to the Pharmacokinetic Study of Ginkgo Biloba Extract in Rats

Tissue Distribution and Cytochrome P450 Inhibition of Sesaminol and Its Tetrahydrofuranoid Metabolites

Discovery and optimization of novel purines as potent and selective CB2 agonists

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