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Total Synthesis of Vinblastine, Related Natural Products, and Key Analogues and Development of Inspired Methodology Suitable for the Systematic Study of Their Structure–Function Properties

Accounts of chemical research, 2015-03, Vol.48 (3), p.653-662

2015

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Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle

Science (American Association for the Advancement of Science), 2018-06, Vol.360 (6394), p.1235-1239

2018

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Completion of the canonical pathway for assembly of anticancer drugs vincristine/vinblastine in Catharanthus roseus

The Plant journal : for cell and molecular biology, 2019-01, Vol.97 (2), p.257-266

2019

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Next Generation Antineoplastic Agents: A Review on Structurally Modified Vinblastine (VBL) Analogues

Current medicinal chemistry, 2018-01, Vol.25 (14), p.1650-1662

2018

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Randomized Phase III Trial of Dose-dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin, or Gemcitabine and Cisplatin as Perioperative Chemotherapy for Patients with Muscle-invasive Bladder Cancer. Analysis of the GETUG/AFU V05 VESPER Trial Secondary Endpoints: Chemotherapy Toxicity and Pathological Responses

European urology, 2021-02, Vol.79 (2), p.214-221

2021

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Total Synthesis of Vinblastine, Vincristine, Related Natural Products, and Key Structural Analogues

Journal of the American Chemical Society, 2009-04, Vol.131 (13), p.4904-4916

2009

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Gefitinib versus vinorelbine plus cisplatin as adjuvant treatment for stage II–IIIA (N1–N2) EGFR-mutant NSCLC (ADJUVANT/CTONG1104): a randomised, open-label, phase 3 study

The lancet oncology, 2018-01, Vol.19 (1), p.139-148

2018

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Phase I Study of Veliparib (ABT-888) Combined with Cisplatin and Vinorelbine in Advanced Triple-Negative Breast Cancer and/or BRCA Mutation-Associated Breast Cancer

Clinical cancer research, 2016-06, Vol.22 (12), p.2855-2864

2016

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Asymmetric Total Synthesis of Vindorosine, Vindoline, and Key Vinblastine Analogues

Journal of the American Chemical Society, 2010-09, Vol.132 (38), p.13533-13544

2010

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Managing common toxicities associated with checkpoint inhibitor and chemotherapy combinations for untreated classic Hodgkin lymphoma

British journal of haematology, 2024-07, Vol.205 (1), p.100-108

2024

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An Endophytic Fungus, Talaromyces radicus, Isolated from Catharanthus roseus, Produces Vincristine and Vinblastine, Which Induce Apoptotic Cell Death

PloS one, 2015-12, Vol.10 (12), p.e0144476-e0144476

2015

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Phase III Randomized Study Comparing Docetaxel Plus Trastuzumab With Vinorelbine Plus Trastuzumab As First-Line Therapy of Metastatic or Locally Advanced Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer: The HERNATA Study

Journal of clinical oncology, 2011-01, Vol.29 (3), p.264-271

2011

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Cevipabulin induced abnormal tubulin protofilaments polymerization by binding to Vinblastine site and The Seventh site

Cytoskeleton (Hoboken, N.J.), 2024-06, Vol.81 (6-7), p.255-263

2024

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Synthesis and Antiproliferative Effect of New Alkyne-Tethered Vindoline Hybrids Containing Pharmacophoric Fragments

International journal of molecular sciences, 2024-07, Vol.25 (13), p.7428

2024

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Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-up

Annals of oncology, 2019-06, Vol.30 (6), p.970-976

2019

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Peptide-conjugated nanoparticles for targeted imaging and therapy of prostate cancer

Biomaterials, 2016-08, Vol.99, p.1-15

2016

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Safety and efficacy of neratinib (HKI-272) plus vinorelbine in the treatment of patients with ErbB2-positive metastatic breast cancer pretreated with anti-HER2 therapy

Annals of oncology, 2013-01, Vol.24 (1), p.109-116

2013

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Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma

The New England journal of medicine, 2017-03, Vol.376 (11), p.1015-1026

2017

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Total Synthesis of (−)-Vindoline and (+)-4-epi-Vindoline Based on a 1,3,4-Oxadiazole Tandem Intramolecular [4 + 2]/[3 + 2] Cycloaddition Cascade Initiated by an Allene Dienophile

Organic letters, 2015-11, Vol.17 (21), p.5460-5463

2015

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Oral Metronomic Vinorelbine in Advanced Non-small Cell Lung Cancer Patients Unfit for Chemotherapy

Anticancer research, 2018-06, Vol.38 (6), p.3689-3697

2018

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Iron(III)/NaBH4-Mediated Additions to Unactivated Alkenes: Synthesis of Novel 20′-Vinblastine Analogues

Organic letters, 2012-03, Vol.14 (6), p.1428-1431

2012

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ABVD Alone versus Radiation-Based Therapy in Limited-Stage Hodgkin's Lymphoma

The New England journal of medicine, 2012-02, Vol.366 (5), p.399-408

2012

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Adapted Treatment Guided by Interim PET-CT Scan in Advanced Hodgkin’s Lymphoma

The New England journal of medicine, 2016-06, Vol.374 (25), p.2419-2429

2016

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Isolation, purification and characterization of vinblastine and vincristine from endophytic fungus Fusarium oxysporum isolated from Catharanthus roseus

PloS one, 2013-09, Vol.8 (9), p.e71805-e71805

2013

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Total Synthesis of Vinblastine, Related Natural Products, and Key Analogues and Development of Inspired Methodology Suitable for the Systematic Study of Their Structure–Function Properties

Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle

Completion of the canonical pathway for assembly of anticancer drugs vincristine/vinblastine in Catharanthus roseus

Next Generation Antineoplastic Agents: A Review on Structurally Modified Vinblastine (VBL) Analogues

Total Synthesis of Vinblastine, Vincristine, Related Natural Products, and Key Structural Analogues

Gefitinib versus vinorelbine plus cisplatin as adjuvant treatment for stage II–IIIA (N1–N2) EGFR-mutant NSCLC (ADJUVANT/CTONG1104): a randomised, open-label, phase 3 study

Phase I Study of Veliparib (ABT-888) Combined with Cisplatin and Vinorelbine in Advanced Triple-Negative Breast Cancer and/or BRCA Mutation-Associated Breast Cancer

Asymmetric Total Synthesis of Vindorosine, Vindoline, and Key Vinblastine Analogues

Brentuximab vedotin with chemotherapy for stage III/IV classical Hodgkin lymphoma: 3-year update of the ECHELON-1 study

Managing common toxicities associated with checkpoint inhibitor and chemotherapy combinations for untreated classic Hodgkin lymphoma

An Endophytic Fungus, Talaromyces radicus, Isolated from Catharanthus roseus, Produces Vincristine and Vinblastine, Which Induce Apoptotic Cell Death

Phase III Randomized Study Comparing Docetaxel Plus Trastuzumab With Vinorelbine Plus Trastuzumab As First-Line Therapy of Metastatic or Locally Advanced Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer: The HERNATA Study

Cevipabulin induced abnormal tubulin protofilaments polymerization by binding to Vinblastine site and The Seventh site

Synthesis and Antiproliferative Effect of New Alkyne-Tethered Vindoline Hybrids Containing Pharmacophoric Fragments

Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-up

Peptide-conjugated nanoparticles for targeted imaging and therapy of prostate cancer

Safety and efficacy of neratinib (HKI-272) plus vinorelbine in the treatment of patients with ErbB2-positive metastatic breast cancer pretreated with anti-HER2 therapy

Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma

Total Synthesis of (−)-Vindoline and (+)-4-epi-Vindoline Based on a 1,3,4-Oxadiazole Tandem Intramolecular [4 + 2]/[3 + 2] Cycloaddition Cascade Initiated by an Allene Dienophile

Oral Metronomic Vinorelbine in Advanced Non-small Cell Lung Cancer Patients Unfit for Chemotherapy

Iron(III)/NaBH4-Mediated Additions to Unactivated Alkenes: Synthesis of Novel 20′-Vinblastine Analogues

ABVD Alone versus Radiation-Based Therapy in Limited-Stage Hodgkin's Lymphoma

Adapted Treatment Guided by Interim PET-CT Scan in Advanced Hodgkin’s Lymphoma

Isolation, purification and characterization of vinblastine and vincristine from endophytic fungus Fusarium oxysporum isolated from Catharanthus roseus

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