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Exploring Intrinsic Disorder in Human Synucleins and Associated Proteins

International journal of molecular sciences, 2024-08, Vol.25 (15), p.8399

2024

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Of Synuclein and Other Demons

Journal of Alzheimer's disease, 2021, Vol.83 (3), p.1391-1393

Espay, Alberto J.

2021

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Feeling the α-synuclein strain

Science translational medicine, 2019-12, Vol.11 (523)

Haigh, Cathryn

2019

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Brain iron enrichment attenuates α‐synuclein spreading after injection of preformed fibrils

Journal of neurochemistry, 2021-11, Vol.159 (3), p.554-573

2021

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Monomeric Synucleins Generate Membrane Curvature

The Journal of biological chemistry, 2013-01, Vol.288 (3), p.1829-1840

2013

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Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease

Neuron (Cambridge, Mass.), 2019-08, Vol.103 (4), p.627-641.e7

2019

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Alpha and Beta Synucleins: From Pathophysiology to Clinical Application as Biomarkers

Movement disorders, 2022-04, Vol.37 (4), p.669-683

2022

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Excess membrane binding of monomeric alpha-, beta- and gamma-synuclein is invariably associated with inclusion formation and toxicity

Human molecular genetics, 2021-11, Vol.30 (23), p.2332-2346

2021

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Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy

Nature (London), 2020-02, Vol.578 (7794), p.273-277

2020

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Residual Structure, Backbone Dynamics, and Interactions within the Synuclein Family

Journal of molecular biology, 2007-09, Vol.372 (3), p.689-707

2007

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Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology

Neurobiology of disease, 2015-07, Vol.79, p.81-99

2015

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Effects of phosphatidylcholine membrane fluidity on the conformation and aggregation of N-terminally acetylated α-synuclein

The Journal of biological chemistry, 2018-07, Vol.293 (28), p.11195-11205

2018

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Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel

Nature communications, 2018-09, Vol.9 (1), p.3609-10, Article 3609

2018

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[alpha]-synuclein astrogliopathy: A possible specific feature in [alpha]-synucleinopathy

Neuropathology, 2017-08, Vol.37 (4), p.379

2017

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Fish Synucleins: An Update

Marine Drugs, 2015-10, Vol.13 (11), p.6665-6686

2015

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N‐terminal acetylation of α‐synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

Protein science, 2012-07, Vol.21 (7), p.911-917

2012

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In Vivo Cross-linking Reveals Principally Oligomeric Forms of α-Synuclein and β-Synuclein in Neurons and Non-neural Cells

The Journal of biological chemistry, 2013-03, Vol.288 (9), p.6371-6385

2013

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The good and bad of therapeutic strategies that directly target α‐synuclein

IUBMB life, 2020-04, Vol.72 (4), p.590-600

2020

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Parkinson’s disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (33), p.20305-20315

2020

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A pH-dependent switch promotes β-synuclein fibril formation via glutamate residues

The Journal of biological chemistry, 2017-09, Vol.292 (39), p.16368-16379

2017

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Antibodies against alpha‐synuclein: tools and therapies

Journal of neurochemistry, 2019-09, Vol.150 (5), p.612-625

2019

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Interplay between tau and α‐synuclein liquid–liquid phase separation

Protein science, 2021-07, Vol.30 (7), p.1326-1336

2021

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Author Correction: Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein

Nature communications, 2024-07, Vol.15 (1), p.6413-3, Article 6413

2024

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Structure, function and toxicity of alpha‐synuclein: the Bermuda triangle in synucleinopathies

Journal of neurochemistry, 2016-10, Vol.139 (S1), p.240-255

2016

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The physiological role of α‐synuclein and its relationship to Parkinson’s Disease

Journal of neurochemistry, 2019-09, Vol.150 (5), p.475-486

2019

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Exploring Intrinsic Disorder in Human Synucleins and Associated Proteins

Of Synuclein and Other Demons

Feeling the α-synuclein strain

Brain iron enrichment attenuates α‐synuclein spreading after injection of preformed fibrils

Monomeric Synucleins Generate Membrane Curvature

Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease

Alpha and Beta Synucleins: From Pathophysiology to Clinical Application as Biomarkers

Excess membrane binding of monomeric alpha-, beta- and gamma-synuclein is invariably associated with inclusion formation and toxicity

Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy

Residual Structure, Backbone Dynamics, and Interactions within the Synuclein Family

Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology

Effects of phosphatidylcholine membrane fluidity on the conformation and aggregation of N-terminally acetylated α-synuclein

Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel

[alpha]-synuclein astrogliopathy: A possible specific feature in [alpha]-synucleinopathy

Fish Synucleins: An Update

N‐terminal acetylation of α‐synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

In Vivo Cross-linking Reveals Principally Oligomeric Forms of α-Synuclein and β-Synuclein in Neurons and Non-neural Cells

The good and bad of therapeutic strategies that directly target α‐synuclein

Parkinson’s disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM

A pH-dependent switch promotes β-synuclein fibril formation via glutamate residues

Antibodies against alpha‐synuclein: tools and therapies

Interplay between tau and α‐synuclein liquid–liquid phase separation

Author Correction: Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein

Structure, function and toxicity of alpha‐synuclein: the Bermuda triangle in synucleinopathies

The physiological role of α‐synuclein and its relationship to Parkinson’s Disease

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