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Chimeric antigen receptors: driving immunology towards synthetic biology

Current opinion in immunology, 2016-08, Vol.41, p.68-76

Sadelain, Michel

2016

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Cytokine release syndrome and associated neurotoxicity in cancer immunotherapy

Nature reviews. Immunology, 2022-02, Vol.22 (2), p.85

2022

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Gene therapy comes of age

Science (American Association for the Advancement of Science), 2018-01, Vol.359 (6372)

2018

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PD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responses

Science translational medicine, 2013-12, Vol.5 (215), p.215ra172

2013

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The promise and potential pitfalls of chimeric antigen receptors

Current opinion in immunology, 2009-04, Vol.21 (2), p.215-223

2009

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The pharmacology of second-generation chimeric antigen receptors

Nature reviews. Drug discovery, 2015-07, Vol.14 (7), p.499-509

2015

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The Journey from Discoveries in Fundamental Immunology to Cancer Immunotherapy

Cancer cell, 2015-04, Vol.27 (4), p.439-449

2015

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Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

The New England journal of medicine, 2018-02, Vol.378 (5), p.449-459

2018

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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Nature biotechnology, 2009-03, Vol.27 (3), p.275-280

2009

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Eliminating Cells Gone Astray

The New England journal of medicine, 2011-11, Vol.365 (18), p.1735-1737

Sadelain, Michel

2011

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CD19 CAR-targeted T cells induce long-term remission and B Cell Aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia

PloS one, 2013-04, Vol.8 (4), p.e61338

2013

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CD19 CAR T Cells

Cell, 2017-12, Vol.171 (7), p.1471-1471

Sadelain, Michel

2017

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The quest for spatio-temporal control of CAR T cells

Cell research, 2015-12, Vol.25 (12), p.1281-1282

2015

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Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition

PloS one, 2015-06, Vol.10 (6), p.e0130518-e0130518

2015

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Clinical Impact of Immune Microenvironment in Stage I Lung Adenocarcinoma: Tumor Interleukin-12 Receptor β2 (IL-12Rβ2), IL-7R, and Stromal FoxP3/CD3 Ratio Are Independent Predictors of Recurrence

Journal of clinical oncology, 2013-02, Vol.31 (4), p.490-498

2013

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Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (34), p.15163-15168

2010

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Impact of bridging chemotherapy on clinical outcome of CD19 CAR T therapy in adult acute lymphoblastic leukemia

Leukemia, 2021-11, Vol.35 (11), p.3268-3271

2021

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1005

Experimental hematology, 2023, Vol.124, p.S22

Sadelain, Michel

2023

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Mesothelin Overexpression Promotes Mesothelioma Cell Invasion and MMP-9 Secretion in an Orthotopic Mouse Model and in Epithelioid Pleural Mesothelioma Patients

Clinical cancer research, 2012-05, Vol.18 (9), p.2478-2489

2012

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Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (31), p.12759-12764

2009

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Genetically Targeted T Cells Eradicate Systemic Acute Lymphoblastic Leukemia Xenografts

Clinical cancer research, 2007-09, Vol.13 (18), p.5426-5435

2007

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Genome Editing Technologies: Defining a Path to Clinic

Molecular therapy, 2015-05, Vol.23 (5), p.796-806

2015

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The Potential of Stem Cells as an In Vitro Source of Red Blood Cells for Transfusion

Cell stem cell, 2012-02, Vol.10 (2), p.115-119

2012

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Chimeric antigen receptors: driving immunology towards synthetic biology

Cytokine release syndrome and associated neurotoxicity in cancer immunotherapy

Gene therapy comes of age

PD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responses

The promise and potential pitfalls of chimeric antigen receptors

The pharmacology of second-generation chimeric antigen receptors

The Journey from Discoveries in Fundamental Immunology to Cancer Immunotherapy

Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Eliminating Cells Gone Astray

CD19 CAR-targeted T cells induce long-term remission and B Cell Aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia

CD19 CAR T Cells

The quest for spatio-temporal control of CAR T cells

HLA-independent T cell receptors for targeting tumors with low antigen density

Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition

Clinical Impact of Immune Microenvironment in Stage I Lung Adenocarcinoma: Tumor Interleukin-12 Receptor β2 (IL-12Rβ2), IL-7R, and Stromal FoxP3/CD3 Ratio Are Independent Predictors of Recurrence

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

Impact of bridging chemotherapy on clinical outcome of CD19 CAR T therapy in adult acute lymphoblastic leukemia

1005

Mesothelin Overexpression Promotes Mesothelioma Cell Invasion and MMP-9 Secretion in an Orthotopic Mouse Model and in Epithelioid Pleural Mesothelioma Patients

Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation

Genetically Targeted T Cells Eradicate Systemic Acute Lymphoblastic Leukemia Xenografts

Genome Editing Technologies: Defining a Path to Clinic

Lentiviral globin gene therapy with reduced-intensity conditioning in adults with β-thalassemia: a phase 1 trial

The Potential of Stem Cells as an In Vitro Source of Red Blood Cells for Transfusion

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