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Base-edited CAR T cells for combinational therapy against T cell malignancies

Leukemia, 2021-12, Vol.35 (12), p.3466-3481

2021

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Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety

Molecular therapy, 2020-06, Vol.28 (6), p.1422-1431

2020

Volltextzugriff (PDF)

Human Coronavirus OC43 Associated with Fatal Encephalitis

The New England journal of medicine, 2016-08, Vol.375 (5), p.497-498

2016

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Genome-edited allogeneic donor “universal” chimeric antigen receptor T cells

Blood, 2023-02, Vol.141 (8), p.835-845

Qasim, Waseem

2023

Volltextzugriff (PDF)

Genome editing approaches for universal chimeric antigen receptor T cells

EJC paediatric oncology, 2024-06, Vol.3, p.100149, Article 100149

2024

Volltextzugriff (PDF)

Allogeneic CAR T cell therapies for leukemia

American journal of hematology, 2019-05, Vol.94 (S1), p.S50-S54

Qasim, Waseem

2019

Volltextzugriff (PDF)

Astrovirus VA1/HMO-C: An Increasingly Recognized Neurotropic Pathogen in Immunocompromised Patients

Clinical infectious diseases, 2015-03, Vol.60 (6), p.881-888

2015

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'Mini' U6 Pol III promoter exhibits nucleosome redundancy and supports multiplexed coupling of CRISPR/Cas9 effects

Gene therapy, 2020-09, Vol.27 (9), p.451-458

2020

Volltextzugriff (PDF)

Gene Therapy for Primary Immunodeficiencies: Current Status and Future Prospects

Drugs (New York, N.Y.), 2014-06, Vol.74 (9), p.963-969

2014

Volltextzugriff (PDF)

How I treat severe combined immunodeficiency

Blood, 2013-11, Vol.122 (23), p.3749-3758

2013

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Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial

Human gene therapy, 2019-09, Vol.30 (9), p.1067

2019

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Paracellular Pathway Enhancement of Metformin Hydrochloride via Molecular Dispersion in Span 60 Microparticles

Frontiers in pharmacology, 2019-07, Vol.10, p.713-713

2019

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CD70 expression determines the therapeutic efficacy of expanded human regulatory T cells

Communications biology, 2020-07, Vol.3 (1), p.375, Article 375

2020

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Mutations in linker for activation of T cells (LAT) lead to a novel form of severe combined immunodeficiency

Journal of allergy and clinical immunology, 2017-02, Vol.139 (2), p.634-642.e5

2017

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Outcome of Non-hematological Autoimmunity After Hematopoietic Cell Transplantation in Children with Primary Immunodeficiency

Journal of clinical immunology, 2021, Vol.41 (1), p.171-184

2021

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Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa

JCI insight, 2019-06, Vol.4 (11)

2019

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Effect of stem cell source on long-term chimerism and event-free survival in children with primary immunodeficiency disorders after fludarabine and melphalan conditioning regimen

Journal of allergy and clinical immunology, 2016-10, Vol.138 (4), p.1152-1160

2016

Volltextzugriff (PDF)

Lentiviral Vector Production Titer Is Not Limited in HEK293T by Induced Intracellular Innate Immunity

Molecular therapy. Methods & clinical development, 2020-06, Vol.17, p.209-219

2020

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Comparison of lentiviral and sleeping beauty mediated αβ T cell receptor gene transfer

PloS one, 2013-06, Vol.8 (6), p.e68201-e68201

2013

Volltextzugriff (PDF)

Gene therapy strategies to exploit TRIM derived restriction factors against HIV-1

Viruses, 2014-01, Vol.6 (1), p.243-263

2014

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Host natural killer immunity is a key indicator of permissiveness for donor cell engraftment in patients with severe combined immunodeficiency

Journal of allergy and clinical immunology, 2014-06, Vol.133 (6), p.1660-1666

2014

Volltextzugriff (PDF)

CRISPR-Mediated Base Conversion Allows Discriminatory Depletion of Endogenous T Cell Receptors for Enhanced Synthetic Immunity

Molecular therapy. Methods & clinical development, 2020-12, Vol.19, p.149-161

2020

Volltextzugriff (PDF)

Genome-Edited T Cell Therapies

Hematology/oncology clinics of North America, 2022-08, Vol.36 (4), p.729-744

2022

Volltextzugriff (PDF)

Cytosine Deaminase Base Editing to Restore COL7A1 in Dystrophic Epidermolysis Bullosa Human: Murine Skin Model

JID innovations, 2023-05, Vol.3 (3), p.100191-100191, Article 100191

2023

Volltextzugriff (PDF)

Production and first-in-man use of T cells engineered to express a HSVTK-CD34 sort-suicide gene

PloS one, 2013-10, Vol.8 (10), p.e77106-e77106

2013

Volltextzugriff (PDF)

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Base-edited CAR T cells for combinational therapy against T cell malignancies

Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety

Human Coronavirus OC43 Associated with Fatal Encephalitis

Genome-edited allogeneic donor “universal” chimeric antigen receptor T cells

Genome editing approaches for universal chimeric antigen receptor T cells

Allogeneic CAR T cell therapies for leukemia

Astrovirus VA1/HMO-C: An Increasingly Recognized Neurotropic Pathogen in Immunocompromised Patients

'Mini' U6 Pol III promoter exhibits nucleosome redundancy and supports multiplexed coupling of CRISPR/Cas9 effects

Gene Therapy for Primary Immunodeficiencies: Current Status and Future Prospects

How I treat severe combined immunodeficiency

Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial

Paracellular Pathway Enhancement of Metformin Hydrochloride via Molecular Dispersion in Span 60 Microparticles

CD70 expression determines the therapeutic efficacy of expanded human regulatory T cells

Mutations in linker for activation of T cells (LAT) lead to a novel form of severe combined immunodeficiency

Outcome of Non-hematological Autoimmunity After Hematopoietic Cell Transplantation in Children with Primary Immunodeficiency

Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa

Effect of stem cell source on long-term chimerism and event-free survival in children with primary immunodeficiency disorders after fludarabine and melphalan conditioning regimen

Lentiviral Vector Production Titer Is Not Limited in HEK293T by Induced Intracellular Innate Immunity

Comparison of lentiviral and sleeping beauty mediated αβ T cell receptor gene transfer

Gene therapy strategies to exploit TRIM derived restriction factors against HIV-1

Host natural killer immunity is a key indicator of permissiveness for donor cell engraftment in patients with severe combined immunodeficiency

CRISPR-Mediated Base Conversion Allows Discriminatory Depletion of Endogenous T Cell Receptors for Enhanced Synthetic Immunity

Genome-Edited T Cell Therapies

Cytosine Deaminase Base Editing to Restore COL7A1 in Dystrophic Epidermolysis Bullosa Human: Murine Skin Model

Production and first-in-man use of T cells engineered to express a HSVTK-CD34 sort-suicide gene

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