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Underlying Mechanisms and Therapeutic Strategies for Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ)

Biological and Pharmaceutical Bulletin, 2017/06/01, Vol.40(6), pp.739-750

2017

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Release of Nitrogen-Containing Bisphosphonates (NBPs) from Hydroxyapatite by Non-NBPs and by Pyrophosphate

Biological and Pharmaceutical Bulletin, 2021/11/01, Vol.44(11), pp.1670-1680

2021

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Histidine decarboxylase deficiency inhibits NBP-induced extramedullary hematopoiesis by modifying bone marrow and spleen microenvironments

International journal of hematology, 2021-03, Vol.113 (3), p.348-361

2021

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Interleukin‐1 and histamine are essential for inducing nickel allergy in mice

Clinical and experimental allergy, 2019-10, Vol.49 (10), p.1362-1373

2019

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Identification of a vesicular ATP release inhibitor for the treatment of neuropathic and inflammatory pain

Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (31), p.E6297-E6305

2017

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The Bisphosphonates Clodronate and Etidronate Exert Analgesic Effects by Acting on Glutamate- and/or ATP-Related Pain Transmission Pathways

Biological and Pharmaceutical Bulletin, 2016/05/01, Vol.39(5), pp.770-777

2016

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IL-33 induces histidine decarboxylase, especially in c-kit+ cells and mast cells, and roles of histamine include negative regulation of IL-33-induced eosinophilia

Inflammation research, 2023-03, Vol.72 (3), p.651-667

2023

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Inflammatory Effects of Nitrogen-Containing Bisphosphonates (N-BPs): Modulation by Non-N-BPs

Biological and Pharmaceutical Bulletin, 2017/01/01, Vol.40(1), pp.25-33

2017

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Dynamics of Platelet Behaviors as Defenders and Guardians: Accumulations in Liver, Lung, and Spleen in Mice

Biological and Pharmaceutical Bulletin, 2019/08/01, Vol.42(8), pp.1253-1267

2019

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Effects of Zoledronate on Local and Systemic Production of IL-1β, IL-18, and TNF-α in Mice and Augmentation by Lipopolysaccharide

Biological and Pharmaceutical Bulletin, 2019/06/01, Vol.42(6), pp.929-936

2019

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Induction of the Histamine-Forming Enzyme Histidine Decarboxylase in Skeletal Muscles by Prolonged Muscular Work: Histological Demonstration and Mediation by Cytokines

Biological and Pharmaceutical Bulletin, 2017/08/01, Vol.40(8), pp.1326-1330

2017

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Augmentation of Lipopolysaccharide-Induced Production of IL-1α and IL-1β in Mice Given Intravenous Zoledronate (a Nitrogen-Containing Bisphosphonate) and Its Prevention by Clodronate (a Non-nitrogen-containing Bisphosphonate)

Biological and Pharmaceutical Bulletin, 2019/02/01, Vol.42(2), pp.164-172

2019

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Changes in histidine decarboxylase expression influence extramedullary hematopoiesis in postnatal mice

Anatomical record (Hoboken, N.J. : 2007), 2021-05, Vol.304 (5), p.1136-1150

2021

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Effect of nitrogen-containing bisphosphonates on osteoclasts and osteoclastogenesis: an ultrastructural study

Microscopy, 2021-06, Vol.70 (3), p.302-307

2021

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Neutrophils Provide a Favorable IL-1-Mediated Immunometabolic Niche that Primes GLUT4 Translocation and Performance in Skeletal Muscles

Cell reports (Cambridge), 2018-05, Vol.23 (8), p.2354-2364

2018

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Phosphonocarboxylates Can Protect Mice against the Inflammatory and Necrotic Side Effects of Nitrogen-Containing Bisphosphonates by Inhibiting Their Entry into Cells via Phosphate Transporters

Biological and Pharmaceutical Bulletin, 2016/05/01, Vol.39(5), pp.712-720

2016

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Analgesic effects of the non-nitrogen-containing bisphosphonates etidronate and clodronate, independent of anti-resorptive effects on bone

European journal of pharmacology, 2013-01, Vol.699 (1-3), p.14-22

2013

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Involvement of IL-1 in the Maintenance of Masseter Muscle Activity and Glucose Homeostasis

PloS one, 2015-11, Vol.10 (11), p.e0143635-e0143635

2015

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Nitrogen-containing bisphosphonate induces a newly discovered hematopoietic structure in the omentum of an anemic mouse model by stimulating G-CSF production

Cell and tissue research, 2017-02, Vol.367 (2), p.297-309

2017

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A Strategy against the Osteonecrosis of the Jaw Associated with Nitrogen-Containing Bisphosphonates (N-BPs): Attempts to Replace N-BPs with the Non-N-BP Etidronate

Biological and Pharmaceutical Bulletin, 2016/09/01, Vol.39(9), pp.1549-1554

2016

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Analgesic Effects of 1st Generation Anti-histamines in Mice

Biological and Pharmaceutical Bulletin, 2016/04/01, Vol.39(4), pp.620-624

2016

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Mast cell histamine-mediated transient inflammation following exposure to nickel promotes nickel allergy in mice

Experimental dermatology, 2016-06, Vol.25 (6), p.466-471

2016

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Nickel allergy-promoting effects of microbial or inflammatory substances at the sensitization step in mice

International immunopharmacology, 2011-10, Vol.11 (10), p.1534-1540

2011

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Lipopolysaccharide-Activated Leukocytes Enhance Thymic Stromal Lymphopoietin Production in a Mouse Air-Pouch-Type Inflammation Model

Inflammation, 2016-08, Vol.39 (4), p.1527-1537

2016

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Anti-inflammatory Effect of Propolis through Inhibition of Nitric Oxide Production on Carrageenin-Induced Mouse Paw Edema

Biological and Pharmaceutical Bulletin, 2006, Vol.29(1), pp.96-99

2006

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Underlying Mechanisms and Therapeutic Strategies for Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ)

Release of Nitrogen-Containing Bisphosphonates (NBPs) from Hydroxyapatite by Non-NBPs and by Pyrophosphate

Histidine decarboxylase deficiency inhibits NBP-induced extramedullary hematopoiesis by modifying bone marrow and spleen microenvironments

Interleukin‐1 and histamine are essential for inducing nickel allergy in mice

Identification of a vesicular ATP release inhibitor for the treatment of neuropathic and inflammatory pain

The Bisphosphonates Clodronate and Etidronate Exert Analgesic Effects by Acting on Glutamate- and/or ATP-Related Pain Transmission Pathways

IL-33 induces histidine decarboxylase, especially in c-kit+ cells and mast cells, and roles of histamine include negative regulation of IL-33-induced eosinophilia

Inflammatory Effects of Nitrogen-Containing Bisphosphonates (N-BPs): Modulation by Non-N-BPs

Dynamics of Platelet Behaviors as Defenders and Guardians: Accumulations in Liver, Lung, and Spleen in Mice

Effects of Zoledronate on Local and Systemic Production of IL-1β, IL-18, and TNF-α in Mice and Augmentation by Lipopolysaccharide

Induction of the Histamine-Forming Enzyme Histidine Decarboxylase in Skeletal Muscles by Prolonged Muscular Work: Histological Demonstration and Mediation by Cytokines

Augmentation of Lipopolysaccharide-Induced Production of IL-1α and IL-1β in Mice Given Intravenous Zoledronate (a Nitrogen-Containing Bisphosphonate) and Its Prevention by Clodronate (a Non-nitrogen-containing Bisphosphonate)

Changes in histidine decarboxylase expression influence extramedullary hematopoiesis in postnatal mice

Effect of nitrogen-containing bisphosphonates on osteoclasts and osteoclastogenesis: an ultrastructural study

Neutrophils Provide a Favorable IL-1-Mediated Immunometabolic Niche that Primes GLUT4 Translocation and Performance in Skeletal Muscles

Phosphonocarboxylates Can Protect Mice against the Inflammatory and Necrotic Side Effects of Nitrogen-Containing Bisphosphonates by Inhibiting Their Entry into Cells via Phosphate Transporters

Analgesic effects of the non-nitrogen-containing bisphosphonates etidronate and clodronate, independent of anti-resorptive effects on bone

Involvement of IL-1 in the Maintenance of Masseter Muscle Activity and Glucose Homeostasis

Nitrogen-containing bisphosphonate induces a newly discovered hematopoietic structure in the omentum of an anemic mouse model by stimulating G-CSF production

A Strategy against the Osteonecrosis of the Jaw Associated with Nitrogen-Containing Bisphosphonates (N-BPs): Attempts to Replace N-BPs with the Non-N-BP Etidronate

Analgesic Effects of 1st Generation Anti-histamines in Mice

Mast cell histamine-mediated transient inflammation following exposure to nickel promotes nickel allergy in mice

Nickel allergy-promoting effects of microbial or inflammatory substances at the sensitization step in mice

Lipopolysaccharide-Activated Leukocytes Enhance Thymic Stromal Lymphopoietin Production in a Mouse Air-Pouch-Type Inflammation Model

Anti-inflammatory Effect of Propolis through Inhibition of Nitric Oxide Production on Carrageenin-Induced Mouse Paw Edema

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