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Lipid phosphate phosphatases and their roles in mammalian physiology and pathology

Journal of lipid research, 2015-11, Vol.56 (11), p.2048-2060

2015

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Lipid phosphate phosphatases and signaling

Journal of lipid research, 2009-04, Vol.50 (Suppl), p.S225-S230

2009

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Lysophosphatidic Acid Signaling in Cancer

Cancers, 2020-12, Vol.12 (12), p.3791

Brindley, David N

2020

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Role of the autotaxin–lysophosphatidate axis in the development of resistance to cancer therapy

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2020-08, Vol.1865 (8), p.158716-158716, Article 158716

2020

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Lipid Phosphate Phosphatases and Cancer

Biomolecules (Basel, Switzerland), 2020-09, Vol.10 (9), p.1263

2020

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Three Mammalian Lipins Act as Phosphatidate Phosphatases with Distinct Tissue Expression Patterns

The Journal of biological chemistry, 2007-02, Vol.282 (6), p.3450-3457

2007

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Role of Adipose Tissue-Derived Autotaxin, Lysophosphatidate Signaling, and Inflammation in the Progression and Treatment of Breast Cancer

International journal of molecular sciences, 2020-08, Vol.21 (16), p.5938

2020

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Role of the autotaxin–lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy

Biochimica et biophysica acta, 2013-01, Vol.1831 (1), p.74-85

2013

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Autotaxin in the crosshairs: Taking aim at cancer and other inflammatory conditions

FEBS letters, 2014-08, Vol.588 (16), p.2712-2727

2014

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Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate

Journal of lipid research, 2015-06, Vol.56 (6), p.1134-1144

2015

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Signalling by lysophosphatidate and its health implications

Essays in biochemistry, 2020-09, Vol.64 (3), p.547-563

2020

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Sensitivity of docetaxel-resistant MCF-7 breast cancer cells to microtubule-destabilizing agents including vinca alkaloids and colchicine-site binding agents

PloS one, 2017-08, Vol.12 (8), p.e0182400-e0182400

2017

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Multiple mechanisms underlying acquired resistance to taxanes in selected docetaxel-resistant MCF-7 breast cancer cells

BMC cancer, 2014-01, Vol.14 (1), p.37-37, Article 37

2014

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Lipid phosphate phosphatases and related proteins: Signaling functions in development, cell division, and cancer

Journal of cellular biochemistry, 2004-08, Vol.92 (5), p.900-912

Brindley, David N.

2004

Volltextzugriff (PDF)

Autotaxin and Breast Cancer: Towards Overcoming Treatment Barriers and Sequelae

Cancers, 2020-02, Vol.12 (2), p.374

2020

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Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: implications for cancer treatment

The FASEB journal, 2015-03, Vol.29 (3), p.772-785

2015

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Phosphorylation of Lipin 1 and Charge on the Phosphatidic Acid Head Group Control Its Phosphatidic Acid Phosphatase Activity and Membrane Association

The Journal of biological chemistry, 2013-04, Vol.288 (14), p.9933-9945

2013

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Infliximab, a Monoclonal Antibody against TNF-α, Inhibits NF-κB Activation, Autotaxin Expression and Breast Cancer Metastasis to Lungs

Cancers, 2023-12, Vol.16 (1), p.52

2023

Volltextzugriff (PDF)

Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice

The FASEB journal, 2014-06, Vol.28 (6), p.2655-2666

2014

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Oxidative stress contributes to the tamoxifen-induced killing of breast cancer cells: implications for tamoxifen therapy and resistance

Scientific reports, 2016-02, Vol.6 (1), p.21164, Article 21164

2016

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Tumor‐induced inflammation in mammary adipose tissue stimulates a vicious cycle of autotaxin expression and breast cancer progression

The FASEB journal, 2015-09, Vol.29 (9), p.3990-4000

2015

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PDGFRα Enhanced Infection of Breast Cancer Cells with Human Cytomegalovirus but Infection of Fibroblasts Increased Prometastatic Inflammation Involving Lysophosphatidate Signaling

International journal of molecular sciences, 2021-09, Vol.22 (18), p.9817

2021

Volltextzugriff (PDF)

Lysophosphatidic Acid Receptor Signaling in the Human Breast Cancer Tumor Microenvironment Elicits Receptor-Dependent Effects on Tumor Progression

International journal of molecular sciences, 2023-06, Vol.24 (12), p.9812

2023

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Coming of Age for Autotaxin and Lysophosphatidate Signaling: Clinical Applications for Preventing, Detecting and Targeting Tumor-Promoting Inflammation

Cancers, 2018-03, Vol.10 (3), p.73

2018

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Autotaxin Inhibition with IOA-289 Decreases Breast Tumor Growth in Mice Whereas Knockout of Autotaxin in Adipocytes Does Not

Cancers, 2023-05, Vol.15 (11), p.2937

2023

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Lipid phosphate phosphatases and their roles in mammalian physiology and pathology

Lipid phosphate phosphatases and signaling

Lysophosphatidic Acid Signaling in Cancer

Role of the autotaxin–lysophosphatidate axis in the development of resistance to cancer therapy

Lipid Phosphate Phosphatases and Cancer

Three Mammalian Lipins Act as Phosphatidate Phosphatases with Distinct Tissue Expression Patterns

Role of Adipose Tissue-Derived Autotaxin, Lysophosphatidate Signaling, and Inflammation in the Progression and Treatment of Breast Cancer

Role of the autotaxin–lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy

Autotaxin in the crosshairs: Taking aim at cancer and other inflammatory conditions

Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate

Signalling by lysophosphatidate and its health implications

Sensitivity of docetaxel-resistant MCF-7 breast cancer cells to microtubule-destabilizing agents including vinca alkaloids and colchicine-site binding agents

Multiple mechanisms underlying acquired resistance to taxanes in selected docetaxel-resistant MCF-7 breast cancer cells

Lipid phosphate phosphatases and related proteins: Signaling functions in development, cell division, and cancer

Autotaxin and Breast Cancer: Towards Overcoming Treatment Barriers and Sequelae

Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: implications for cancer treatment

Phosphorylation of Lipin 1 and Charge on the Phosphatidic Acid Head Group Control Its Phosphatidic Acid Phosphatase Activity and Membrane Association

Infliximab, a Monoclonal Antibody against TNF-α, Inhibits NF-κB Activation, Autotaxin Expression and Breast Cancer Metastasis to Lungs

Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice

Oxidative stress contributes to the tamoxifen-induced killing of breast cancer cells: implications for tamoxifen therapy and resistance

Tumor‐induced inflammation in mammary adipose tissue stimulates a vicious cycle of autotaxin expression and breast cancer progression

PDGFRα Enhanced Infection of Breast Cancer Cells with Human Cytomegalovirus but Infection of Fibroblasts Increased Prometastatic Inflammation Involving Lysophosphatidate Signaling

Lysophosphatidic Acid Receptor Signaling in the Human Breast Cancer Tumor Microenvironment Elicits Receptor-Dependent Effects on Tumor Progression

Coming of Age for Autotaxin and Lysophosphatidate Signaling: Clinical Applications for Preventing, Detecting and Targeting Tumor-Promoting Inflammation

Autotaxin Inhibition with IOA-289 Decreases Breast Tumor Growth in Mice Whereas Knockout of Autotaxin in Adipocytes Does Not

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