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Structure−Activity Relationships for 5-Substituted 1-Phenylbenzimidazoles as Selective Inhibitors of the Platelet-Derived Growth Factor Receptor

Journal of medicinal chemistry, 1999-07, Vol.42 (13), p.2373-2382

1999

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Soluble 2-Substituted Aminopyrido[2,3-d]pyrimidin-7-yl Ureas. Structure−Activity Relationships against Selected Tyrosine Kinases and Exploration of in Vitro and in Vivo Anticancer Activity

Journal of medicinal chemistry, 2001-06, Vol.44 (12), p.1915-1926

2001

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In vitro pharmacological characterization of PD 166285, a new nanomolar potent and broadly active protein tyrosine kinase inhibitor

The Journal of pharmacology and experimental therapeutics, 1997-12, Vol.283 (3), p.1433

1997

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In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase

The Journal of pharmacology and experimental therapeutics, 1998-07, Vol.286 (1), p.569

1998

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Design and synthesis of potent, selective, and orally active fluorine-containing renin inhibitors

Journal of medicinal chemistry, 1992-01, Vol.35 (1), p.2-14

1992

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INHIBITION OF FGF-1 RECEPTOR TYROSINE KINASE ACTIVITY BY PD 161570, A NEW PROTEIN-TYROSINE KINASE INHIBITOR

Life sciences (1973), 1998, Vol.62 (2), p.143-150

1998

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Inhibition of growth factor-mediated tyrosine phosphorylation in vascular smooth muscle by PD 089828, a new synthetic protein tyrosine kinase inhibitor

The Journal of pharmacology and experimental therapeutics, 1997-06, Vol.281 (3), p.1446

1997

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Synthesis and Structure−Activity Relationships of 7-Substituted 3-(2,6-Dichlorophenyl)-1,6-naphthyridin-2(1H)-ones as Selective Inhibitors of pp60 c -src

Journal of medicinal chemistry, 2000-08, Vol.43 (16), p.3134-3147

2000

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Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors

Journal of medicinal chemistry, 1992-07, Vol.35 (14), p.2562-2572

1992

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Synthesis and Tyrosine Kinase Inhibitory Activity of a Series of 2-Amino-8H-pyrido[2,3-d]pyrimidines: Identification of Potent, Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors

Journal of medicinal chemistry, 1998-10, Vol.41 (22), p.4365-4377

1998

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Peptidomimetic inhibitors of renin incorporating topographically modified isosteres spanning the P1(→P3)-P1' sites

Bioorganic & medicinal chemistry letters, 1993-10, Vol.3 (10), p.2119-2124

1993

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Exploring the binding preferences/specificity in the active site of human cathepsin E

Proteins, structure, function, and bioinformatics, 1995-06, Vol.22 (2), p.168-181

1995

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Synthesis and Structure−Activity Relationships of 7-Substituted 3-(2,6-Dichlorophenyl)-1,6-naphthyridin-2(1H)-ones as Selective Inhibitors of pp60c-src

Journal of medicinal chemistry, 2000-08, Vol.43 (16), p.3134-3147

2000

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Design and Synthesis of Renin Inhibitors: Incorporation of Transition-State Isostere Side Chains That Span from the S1 to the S3 Binding Pockets and Examination of P3-Modified Renin Inhibitors

Journal of medicinal chemistry, 1995-07, Vol.38 (15), p.2893-2905

1995

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Synthesis and Tyrosine Kinase Inhibitory Activity of a Series of 2-Amino-8 H -pyrido[2,3- d ]pyrimidines: Identification of Potent, Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors

Journal of medicinal chemistry, 1998-10, Vol.41 (22), p.4365-4377

1998

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Specificity in the binding of inhibitors to the active site of human/primate aspartic proteinases: analysis of P2-P1-P1'-P2' variation

Journal of medicinal chemistry, 1993-09, Vol.36 (18), p.2614-2620

1993

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Renin inhibitors containing .alpha.-heteroatom amino acids as P2 residues

Journal of medicinal chemistry, 1992-03, Vol.35 (6), p.1032-1042

1992

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Peptidomimetic inhibitors of renin incorporating topographically modified isosteres spanning the P 1(→ P 3)-P 1' sites

Bioorganic & medicinal chemistry letters, 1993-10, Vol.3 (10), p.2119-2124

1993

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New inhibitors of human renin that contain novel replacements at the P2 site

Journal of medicinal chemistry, 1991-04, Vol.34 (4), p.1258-1271

1991

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Disparity Between Blood Pressure and PRA Inhibition After Administration of a Renin Inhibitor to Anesthetized Dogs: Methodological Considerations

Clinical and experimental hypertension (1993), 1993-01, Vol.15 (4), p.663-681

1993

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Ethnic cultural value typologies and mental health parameters among Indians

International journal of intercultural relations, 2022-01, Vol.86, p.95-108

2022

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Structure of the O antigen of Escherichia coli K-12 and the sequence of its rfb gene cluster

Journal of Bacteriology, 1994-07, Vol.176 (13), p.4144-4156

1994

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In vitro reactivity of penicilloyl and penicillanyl albumin and polylysine conjugates with IgE-antibody

Journal of immunological methods, 2000-08, Vol.242 (1), p.43-51

2000

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Towards Genomic Selection in Oilseed Brassica

Genetics, Genomics and Breeding of Oilseed Brassicas, 2012, Vol.1, p.219-229

1, 2012

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Structure−Activity Relationships for 5-Substituted 1-Phenylbenzimidazoles as Selective Inhibitors of the Platelet-Derived Growth Factor Receptor

Soluble 2-Substituted Aminopyrido[2,3-d]pyrimidin-7-yl Ureas. Structure−Activity Relationships against Selected Tyrosine Kinases and Exploration of in Vitro and in Vivo Anticancer Activity

In vitro pharmacological characterization of PD 166285, a new nanomolar potent and broadly active protein tyrosine kinase inhibitor

In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase

Design and synthesis of potent, selective, and orally active fluorine-containing renin inhibitors

INHIBITION OF FGF-1 RECEPTOR TYROSINE KINASE ACTIVITY BY PD 161570, A NEW PROTEIN-TYROSINE KINASE INHIBITOR

Inhibition of growth factor-mediated tyrosine phosphorylation in vascular smooth muscle by PD 089828, a new synthetic protein tyrosine kinase inhibitor

Synthesis and Structure−Activity Relationships of 7-Substituted 3-(2,6-Dichlorophenyl)-1,6-naphthyridin-2(1H)-ones as Selective Inhibitors of pp60 c -src

Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors

Synthesis and Tyrosine Kinase Inhibitory Activity of a Series of 2-Amino-8H-pyrido[2,3-d]pyrimidines: Identification of Potent, Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors

Peptidomimetic inhibitors of renin incorporating topographically modified isosteres spanning the P1(→P3)-P1' sites

Exploring the binding preferences/specificity in the active site of human cathepsin E

Synthesis and Structure−Activity Relationships of 7-Substituted 3-(2,6-Dichlorophenyl)-1,6-naphthyridin-2(1H)-ones as Selective Inhibitors of pp60c-src

Design and Synthesis of Renin Inhibitors: Incorporation of Transition-State Isostere Side Chains That Span from the S1 to the S3 Binding Pockets and Examination of P3-Modified Renin Inhibitors

Synthesis and Tyrosine Kinase Inhibitory Activity of a Series of 2-Amino-8 H -pyrido[2,3- d ]pyrimidines: Identification of Potent, Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors

Specificity in the binding of inhibitors to the active site of human/primate aspartic proteinases: analysis of P2-P1-P1'-P2' variation

Renin inhibitors containing .alpha.-heteroatom amino acids as P2 residues

Peptidomimetic inhibitors of renin incorporating topographically modified isosteres spanning the P 1(→ P 3)-P 1' sites

New inhibitors of human renin that contain novel replacements at the P2 site

Disparity Between Blood Pressure and PRA Inhibition After Administration of a Renin Inhibitor to Anesthetized Dogs: Methodological Considerations

Ethnic cultural value typologies and mental health parameters among Indians

Structure of the O antigen of Escherichia coli K-12 and the sequence of its rfb gene cluster

In vitro reactivity of penicilloyl and penicillanyl albumin and polylysine conjugates with IgE-antibody

Towards Genomic Selection in Oilseed Brassica

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